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Every day roughly three new stroke suspects are rushed by ambulance to Helsinki University Hospital Emergency Department to be considered for urgent clot-busting thrombolytic therapy or thrombectomy to prevent permanent stroke caused by acute cerebral ischemia. But perilously, out of one hundred such 'thrombolysis candidates' only half is actually caused by this condition and the rest have other kinds of diagnoses. Despite the tremendous time-pressure, the rapid diagnoses need to be accurate.
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Post-traumatic stress disorder (PTSD) may increase the risk for stroke and heart attack in both male and female city workers and volunteers who cleaned debris in the aftermath of the World Trade Center plane attack on Sept. 11, 2001. The study sheds light on long-term consequences of PTSD 11-15 years after the event occurred in a general population.
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Researchers have found that inhibiting a receptor on immune cells called macrophages may help relieve pain in some patients, particularly those with chronic neuropathic pain, such as those with conditions such as diabetic neuropathy.
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Scientists have uncovered a potential approach to treat one of the commonest causes of dementia and stroke in older people. Studies with rats found the treatment can reverse changes in blood vessels in the brain associated with the condition, called cerebral small vessel disease. Treatment also prevents damage to brain cells caused by these blood vessel changes, raising hope that it could offer a therapy for dementia.
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A low-dose aspirin regimen may represent a new avenue for reducing Alzheimer's disease pathology, according to new research in a mouse model. The study identifies a new role for one of the most widely used medications in the world.
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Stopping long-term opioid treatment does not make chronic, non-cancer-related pain worse and, in some cases, makes it better, researchers have found.
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The strongest genetic risk factor for Alzheimer's disease may impair the brain's ability to convert its primary fuel source into usable energy, finds a study of female mice. The research suggests therapeutic strategies that promote brain energy conversion in risk gene carriers could help to reduce risk or delay onset of the disease.
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Deep brain stimulation (DBS) may slow the progression of tremor for early-stage Parkinson's disease patients, according to a new study.
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Sound and object motion can be used to change perceptions about body size, according to a new study by an international team involving UCL researchers.
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Two pathways in the brain converging at the amygdala regulate the anxiety and depression that often accompanies chronic pain, suggests research in male rats. One of these pathways may represent a top-down mechanism that controls negative emotion under stress.
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