Investigators have found that instituting combination antiretroviral treatment at the earliest stages of HIV infection may allow the generation of functional CD8 'killer' T cells and preservation of the CD4 helper T cells that are the virus's primary target.
Increasing access to mental health services improves HIV outcomes among vulnerable patients, a new study suggests. Based on their findings, the researchers are urging HIV clinics to expand their mental health services on site.
People with HIV who drink too much were more likely to reduce drinking after undergoing an approach to care known as integrated stepped alcohol treatment, according to a new study. The finding supports greater use of this treatment model in HIV clinics to improve outcomes for patients with both HIV and drinking problems, the researchers said.
In a new study, researchers show how skin vaccination can generate protective CD8 T-cells that are recruited to the genital tissues and could be used as a vaccination strategy for sexually transmitted infections (STIs).
Investigators tested a laboratory-made version of a naturally occurring protein (recombinant fragment of human Surfactant Protein D or rfhSP-D) on bioengineered vaginal tissues, immune cells and microbes to determine if the drug candidate could help prevent HIV transmission safely.
Investigators have used a novel approach to identify specific amino acids in the protein structure of HIV that appear critical to the ability of the virus to function and replicate. They also have found that the immune systems of individuals naturally able to control HIV infection target these amino acids with pathogen-killing CD8 T cells.
New studies have found for the first time that HIV can be transmitted through the sharing of equipment used to prepare drugs before injection and that a simple intervention - heating the equipment with a cigarette lighter for 10 seconds - can destroy the HIV virus, preventing that transmission. The findings, used to inform a public health campaign called 'Cook Your Wash,' have helped reduce rates of HIV transmission in London, Ontario.