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CBD Oils and Auto-Immune DiseasesWhat Are Auto-Immune Diseases?

CBD oil usually comes in a bottle with a dropper and can be taken under the tongue or mixed in with food or drink

CBD oil and other byproducts (such as CBD tinctures or CBD extracts) can help patients suffering from a wide range of conditions, like epilepsy, PTSD or anxiety. Recent research has shown that CBD’s anti-inflammatory properties can help those who suffer from autoimmune diseases as well. Is that possible? Let’s find out!

According to the American Autoimmune Related Diseases Association (AARDA), autoimmune diseases are a series of chronic illnesses that involve almost every human organ system. More than 24 million people in the US alone suffer from some type of autoimmune disease (about 7% of the total population). These disorders seem to be more prevalent in women rather than men, with female patients accounting for two-thirds of all cases.

Autoimmune diseases can occur for no apparent reason and affect the immune system. Under normal circumstances, our immune system protects us from harmful bacteria and viruses that enter the organism. In cases of autoimmune diseases, however, the body mistakes its own healthy tissue and cells as pathogens and produces antibodies and T-Cells to fight them. This results in an inflammatory reaction from the affected area, that causes pain and discomfort. Most autoimmune diseases aren’t curable, so patients have to live with their condition, and treat it with strong medicine.

Common Autoimmune Conditions

AARDA has listed about 150 autoimmune conditions that affect all parts of the body. However, only a few of them are responsible for most cases. The most common autoimmune disorders are:

  • Rheumatoid Arthritis

  • Lupus

  • Inflammatory bowel diseases

  • Hashimoto’s disease

  • Addison’s disease

  • Graves’ disease

  • Multiple sclerosis

  • Type 1 diabetes

  • Sjögren’s syndrome

All of these disorders cause severe inflammation in different parts of the body, that is usually treated with immuno-suppressants and anti-inflammatory medication. These drugs are highly potent and can potentially have harmful side-effects.

And this is where hemp comes in: Researchers believe that cannabidiol’s anti-inflammatory and anti-oxidant properties can be the catalyst for autoimmune patients. But how much truth is there in this statement?

How Can CBD Oil Help With Autoimmune Diseases

CBD is a naturally occurring compound of the cannabis plant and is explicitly extracted from low-THC strains (hemp). THC and CBD are the two most prevalent among hundreds of cannabinoids found naturally in marijuana, and their roles are entirely different: THC is psychoactive and is responsible for the “high” associated with marijuana consumption. CBD however, works antagonistically with THC and provides a non-psychoactive, relaxing feeling that comes with a host of health benefits to the user.

CBD is often extracted from legally grown hemp (which is essentially low-THC cannabis) and comes in a wide assortment of products, such as CBD oil, CBD tinctures, isolates, and extracts. Research has shown that CBD works by interacting directly with specific receptors within our body, sscientists call the endocannabinoid system (ECS)!

The Endocannabinoid System

When we talk about the endocannabinoid system, we must think of it as a collection of cell receptors and molecules that are distributed throughout our body. These receptors are designed to work with specific chemical compounds (in this case, endocannabinoids). The two primary receptors of the ECS are called CB1 and CB2. Whenever cannabinoids interact with one of these two receptors, neurotransmitters release messages to the cells, guiding their moves.

Endocannabinoids are essentially compound similar to the ones found in the cannabis plant. Two of the most prevalent are anandamide and AG-2. These chemical compounds regulate many fundamental body functions such as:

  • Sleep

  • Appetite

  • Mood

  • Immune system

  • Pleasure and reward

  • Pain

  • Memory

Essentially, endocannabinoids maintain an internal balance on the body called homeostasis. When this balance is disrupted, bad things can happen. And this is precisely where phytocannabinoids such as CBD comes into play.

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Duracon CBD Oil Blog by Beth Farmer - 9M ago

Diabetes: What is it, What Causes it, and Who is at Risk

Diabetes is a disease wherein the body has trouble regulating the level of sugar (glucose) in the bloodstream. In healthy individuals, the pancreas produces a hormone called insulin, which works to transport glucose molecules across cell membranes and into cells for energy production.

And of course, without energy sources, the body’s cells (which are responsible for every functional mechanism of life) will be unable to carry out the requisite pathways needed to survive.

In the case of Type 1 diabetics (who only make up about 5% of the diabetic population), the body is no longer able to produce insulin, which is the keystone hormone needed to transfer glucose molecules from the bloodstream into cells. This is generally due to an autoimmune attack on the pancreas – the organ responsible for the production of insulin. Type 1 diabetes usually arises in children or young adults who contract a pancreas-attacking virus, and other than perhaps a genetic predisposition, there are not many specific risk factors.

Type 2 diabetes is a rather more complex form of the disease wherein the body still produces insulin, but it either doesn’t produce enough of it, or the cells become resistant to its physiological pathways. Either way, the resulting effect is similar to that of Type 1 diabetes, wherein the underlying issue is a general inability to control blood glucose levels.

Also, Type 2 diabetes is a far more prevalent form of the disease; it is estimated to affect over 400 million people worldwide, or between 90 and 95% of the total diabetic population.

Additionally, far more risk factors are associated with Type 2 diabetes than there are with Type 1. Several of the most prominent of these factors include: weight (obesity); a high sugar diet combined with inactivity; family history/genetics; ethnicity (African-Americans, Hispanics, and American Indians are especially susceptible, though the reason is unknown); and age (people over 45 are far more likely to develop the disease).

Conventional Non CBD Treatment Methods

In both Type 1 and Type 2 diabetes, an inability for glucose to be absorbed into the body’s cells results in it building up to dangerously high levels in the bloodstream. This results in the severe, potentially life-threatening symptoms that are most often associated with the disease. Some of these symptoms include:

Heart and blood vessel disease

Nerve damage

Stroke

Kidney disease

Vision problems

In short, there aren’t many areas of the body that go unaffected by the physiological detriments of diabetes, and unless the disease is monitored closely on a daily basis, the average diabetic will have a lifespan between 10 and 15 years shorter than the average person’s.

Fortunately, conventional medications have gotten to the point where diabetics – if they keep track of their glucose levels rigorously and maintain an appropriate diet – can lead a rather normal lifestyle.

Since they can’t produce it on their own, most Type 1 diabetics will be prescribed insulin either in the form of shots that they have to self-administer, or in the form of a pump which automatically monitors blood glucose levels and injects the hormone as needed.

While these forms of treatment are state of the art, they’re by no means 100% effective; even the most responsible of diabetics can find it difficult to avoid the dangerous consequences of irregular glucose levels.

And not to mention, without top of the line health insurance, treatments like insulin pumps are far too expensive for the average individual to consider; most, in fact, are resorted to pricking blood from their finger to monitor sugar levels, and self-administering insulin shots through hypodermic needles.

In the case of Type 2 diabetes, individuals who are able to get by without having to take insulin shots will most likely be prescribed a pharmaceutical drug like Metformin or Avandia, which aid in the ability to properly regulate glucose.

However, as is far too common with these kinds of prescription meds, a range of severe side effects is often produced, as is a monthly medical bill that can seemingly be as cumbersome as the side effects themselves.

This is why thousands of diabetics in recent years have been more than willing to try alternative treatment options like CBD oil. Even if it can replace one of their prescription medications, it’s generally more than worth it.

Not to mention, the general improvement in quality of life for diabetics that’ve added CBD to their treatment regimen has been consistent nearly across the board.

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CBD oil and other byproducts (such as CBD tinctures or CBD extracts) can help patients suffering from a wide range of conditions, like epilepsy, PTSD or anxiety. Recent research has shown that CBD’s anti-inflammatory properties can help those who suffer from autoimmune diseases as well. Is that possible? Let’s find out!

What Are Auto-Immune Diseases?

CBD oil usually comes in a bottle with a dropper and can be taken under the tongue or mixed in with food or drink

According to the American Autoimmune Related Diseases Association (AARDA), autoimmune diseases are a series of chronic illnesses that involve almost every human organ system. More than 24 million people in the US alone suffer from some type of autoimmune disease (about 7% of the total population). These disorders seem to be more prevalent in women rather than men, with female patients accounting for two-thirds of all cases.

Autoimmune diseases can occur for no apparent reason and affect the immune system. Under normal circumstances, our immune system protects us from harmful bacteria and viruses that enter the organism. In cases of autoimmune diseases, however, the body mistakes its own healthy tissue and cells as pathogens and produces antibodies and T-Cells to fight them. This results in an inflammatory reaction from the affected area, that causes pain and discomfort. Most autoimmune diseases aren’t curable, so patients have to live with their condition, and treat it with strong medicine.

Common Autoimmune Conditions

AARDA has listed about 150 autoimmune conditions that affect all parts of the body. However, only a few of them are responsible for most cases. The most common autoimmune disorders are:

  • Rheumatoid Arthritis
  • Lupus
  • Inflammatory bowel diseases
  • Hashimoto’s disease
  • Addison’s disease
  • Graves’ disease
  • Multiple sclerosis
  • Type 1 diabetes
  • Sjögren’s syndrome

All of these disorders cause severe inflammation in different parts of the body, that is usually treated with immunosuppressants and anti-inflammatory medication. These drugs are highly potent and can potentially have harmful side-effects.

And this is where hemp comes in: Researchers believe that cannabidiol’s anti-inflammatory and anti-oxidant properties can be the catalyst for autoimmune patients. But how much truth is there in this statement?

 

How Can CBD Oil Help With Autoimmune Diseases

 

CBD is a naturally occurring compound of the cannabis plant and is explicitly extracted from low-THC strains (hemp). THC and CBD are the two most prevalent among hundreds of cannabinoids found naturally in marijuana, and their roles are entirely different: THC is psychoactive and is responsible for the “high” associated with marijuana consumption. CBD however, works antagonistically with THC and provides a non-psychoactive, relaxing feeling that comes with a host of health benefits to the user.

CBD is often extracted from legally grown hemp (which is essentially low-THC cannabis) and comes in a wide assortment of products, such as CBD oil, CBD tinctures, isolates, and extracts. Research has shown that CBD works by interacting directly with specific receptors within our body, specially designed to work in tandem with cannabinoids. This collection of receptors and neurotransmitters is what scientists call the endocannabinoid system (ECS)!

The Endocannabinoid System

When we talk about the endocannabinoid system, we must think of it as a collection of cell receptors and molecules that are distributed throughout our body. These receptors are designed to work with specific chemical compounds (in this case, endocannabinoids). The two primary receptors of the ECS are called CB1 and CB2. Whenever cannabinoids interact with one of these two receptors, neurotransmitters release messages to the cells, guiding their moves.

Endocannabinoids are essentially compound similar to the ones found in the cannabis plant. Two of the most prevalent are anandamide and AG-2. These chemical compounds regulate many fundamental body functions such as:

  • Sleep
  • Appetite
  • Mood
  • Immune system
  • Pleasure and reward
  • Pain
  • Memory

Essentially, endocannabinoids maintain an internal balance on the body called homeostasis. When this balance is disrupted, bad things can happen. And this is precisely where phytocannabinoids such as CBD comes into play.

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We seem to live in an era where we stumble from one health crisis to the next. Along with the antibiotic-resistant bacteria and opioid epidemics, we also have the chronic inflammation and chronic inflammatory disease crisis. There has been a significant change in our diets, lifestyle, and food supply, and the result is a decline in general health.

Inflammation is our body’s natural response to harmful cells and pathogens. It acts as a protective measure against the initial damage suffered by the immune system. The condition is divided into Acute & Chronic categories. Acute inflammation is caused by injured tissues or bacterial pathogens whereas chronic inflammation is caused by consistent acute inflammations or foreign agents.

We need a new way to fight the problem as pharmaceuticals are not getting the job done. Could CBD be our secret weapon against inflammation?

Traditional Inflammation Treatments & Their Side Effects

Inflammation is attributed to a variety of medical conditions with heart disease and cancer among the most serious. It is also associated with:

  • Bone diseases such as osteoporosis
  • Metabolic disorder complications such as type 2 diabetes.
  • Chronic inflammatory diseases such as COPD and IBD.
  • Neurological disorders such as Alzheimer’s and Parkinson’s.

Statistics surrounding our health in the United States make for grim reading:

  • 8% of the population has diabetes.
  • 43 million Americans are afflicted with arthritis and joint disease.
  • Over 5 million Americans have Alzheimer’s disease.
  • The rate of obesity in American adults is 66%. Johns Hopkins School of Medicine believes that at the current rate of increase, every American adult will be obese by 2048!

The list goes on and on

Non-steroidal Anti-inflammatory Drugs (NSAIDs) are the most common pharmaceutical treatment for inflammation. They include:

  • Aspirin
  • Ibuprofen
  • Celecoxib
  • Oxaprozin
  • Piroxicam

One of the main issues with NSAIDs such as Aspirin and Ibuprofen, in particular, is that people take them without realizing the formidable range of side effects such as:

  • Vomiting
  • Nausea
  • Constipation
  • Diarrhea
  • Rash
  • Dizziness
  • Drowsiness

More serious side effects include possible liver and kidney failure, ulcers and prolonged bleeding after sustaining an injury or after surgery. Even more worryingly, NSAIDs increase the risk of potentially fatal strokes and heart attacks. Given the problems associated with these pharmaceutical drugs, it is hardly surprising to learn that patients are desperately seeking alternatives such as CBD for their inflammation worries.

 

How Can CBD Help With Inflammation?

The simple answer is to change our diets and increase our Omega 3 index levels. However, the solution isn’t as basic as that for an increasing percentage of Americans. CBD is long associated with anti-inflammatory and immunosuppressive qualities, and the clamor for this cannabinoid has increased significantly since the FDA approved it as a food supplement.

The two main cannabinoid receptors in your nervous system are CB1 and CB2. While THC is more effective when dealing with CB1 (controls perception, mood, sleep, memory, and appetite), CBD has a greater impact on the CB2 receptor (affects the immune system). Since inflammation is an ‘immune response,’ it is important for any compound to focus on the CB2 receptor to reduce inflammation. While CBD is not the only known cannabis compound to activate the CB2 receptor, it is the most abundant.

The Research on CBD

Arguably the most exciting studies relating to CBD and inflammation have shown that it is the strongest of all anti-inflammatory options, beating off stiff competition from Omega-3, vitamin C, and various antioxidants.

Several compounds within marijuana help reduce inflammation, but CBD is arguably the most effective. One significant study was performed on mice at the Imperial College London and showed that CBD possessed powerful anti-inflammatory capabilities. The researchers found that when the mice received 5mg/kg of CBD, their inflammation was reduced by up to 50%. Oddly enough, the anti-inflammatory effects of CBD were negligible when the mice received 25mg/kg.

A 2011 study by GW Booz looked at the impact of CBD on the inflammation caused by oxidative stress. The conclusion was that cannabidiol was effective and reduced the risk of organ damage and dysfunction.

A 2015 study by Alshaaraway and Anthony looked at the levels of inflammation in people who smoked marijuana and compared them to those who didn’t. They looked at 1,115 people who recently smoked marijuana and 8,041 non-smokers, and the goal was to examine the influence of the plant on C-reactive protein (CRP), an inflammation marker that is often linked to an increased risk of heart disease. The study found that people who had smoked marijuana within the previous 30 days had lower CRP levels than non-smokers.

 

Final Thoughts on CBD for Inflammation

Inflammation is extremely painful and inconvenient at best. At worst, it is a sign that you’re suffering from a serious medical problem. While NSAIDs provide you with reasonably fast-acting relief, the positive effects are only temporary and are often accompanied by awful side effects.

In contrast, CBD is all-natural and it comes in a variety of forms including; oils, gummies, edibles, tinctures, ointments and more. If inflammation is making your life hell, CBD products can help to soothe your pain.

 

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Cannabidiol (CBD) oil is used by some people with chronic pain. CBD oil may reduce pain, inflammation, and overall discomfort related to a variety of health conditions. CBD oil is a product made from cannabis. It’s a type of cannabinoid, a chemical found naturally in marijuana and hemp plants. It doesn’t cause the “high” feeling often associated with cannabis, which is caused by a different type of cannabinoid called THC.

Studies on CBD oil and pain management have shown a great deal of promise. CBD can offer an alternative for people who have chronic pain and rely on more dangerous, habit-forming medications like opioids.

CBD for chronic pain relief

Researchers think that CBD interacts with receptors in your brain and immune system. Receptors are tiny proteins attached to your cells that receive chemical signals from different stimuli and help your cells respond. This creates anti-inflammatory and painkilling effects that help with pain management. This means that CBD oil may benefit people with chronic pain, such as chronic back pain.

One 2008 review assessed how good CBD works to relieve chronic pain. The review looked at studies conducted between the late 1980s and 2007. Based on these reviews, researchers concluded CBD was effective in overall pain management without adverse side effects. They also noted that CBD was beneficial in treating insomnia related to chronic pain.

The authors of the study also noted that CBD was most helpful in people with multiple sclerosis (MS).

CBD for arthritis pain relief

A 2016 study looked at the use of CBD in rats with arthritis. Researchers applied CBD gel to rats for four days in a row. They applied 0.6, 3.1, 6.2, and 62.3 milligrams per day. The researchers noted reduced inflammation and overall pain in the rats’ affected joints without side effects.

CBD for cancer treatment relief

CBD oil is also used by some people who have cancer. A few studies in mice have shown a reduction of cancerous tumors. But most human studies have involved research into the role of CBD oil in managing pain related to cancer and cancer treatment. The National Cancer Institute (NCI) has pointed to CBD as a possible option for relieving symptoms caused by chemotherapy.

One study by the NCI tested CBD oil extracts sprayed into the mouth. The CBD oil was used in conjunction with opioids. This study revealed better pain management with the help of CBD oil. But more research is still needed.

 

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