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I am doing the Ketogenic diet and I bought Dr. Josh Axe's newest book, "Keto Diet" His book has proven to burn fat, reduce inflammation, fight cancer, balance hormones and gut bacteria, improve neurological diseases, and even increase lifespan. Inside,  you will find:
  • shopping lists
  • delicious recipes & menus
  • exercise routines
  • accessible explanations of the science behind keto's powerful effects
  • five different keto plans and a guide to choosing the one that fits you best!
What Is a Ketogenic Diet? - YouTube
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Most likely herbs are part of your kitchen cabinet. Most definitely, your ancestors used herbs as medicine, they may have used it to enhance their food, but today we use herbs to season our food.

Using Herbs as Medicine are not the same as spices. Herbs generally refer to the leafy green or flowering part of a plant – fresh or dried. Thyme, Basil, Cilantro, Bay, Fennel, Lavender, Oregano or Mint are examples of herbs you might already know well. Your ancestors were smarter than you might realise. They used herbs as an anti-inflammatory, antioxidant, anti-thrombotic an anti-hypertensive. They also used is to regulate glucose and help protect your nervous system. Modern science is now finding out that herbs contain something called polyphenols. Polyphenols help fight inflammation and oxidative damage caused by stress, aging & poor lifestyles. These polyphenols are the reason for an improvement in your symptoms.
Ashwagandha, for example, is an adaptogenic herb that can help reduce your cortisol levels. Barberry can help fight infections as it acts as an antifungal and antibacterial. Basil acts as an anti-inflammatory. Bay leaves, commonly used in Indian cooking acts as an antimicrobial, antifungal and antioxidant. Cardamom can supply eighty percent of your daily requirement of manganese and also lower your blood pressure. Feverfew is used to ease the pain from a migraine attack as well as arthritis pain. Kava helps in alleviating anxiety and insomnia.
Now maybe you might look at herbs in your kitchen differently. People today have become too accustomed to instant relief. Waiting a few days to relieve a symptom is intolerable. There is a straightforward solution – if you know your ailment, include the relevant herbs in your diet. There are virtually no side effects.

A Purveyor of sustainable organic ingredients is www.mountainroseherbs.com/
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I am a Kombucha drinker. I buy it a lot and usually not just one company but the one that's on sale  It's not cheap, but I am finding out that eating clean is never cheap. So I have been thinking of making my own, a great project! Kind of like canning fresh vegetables but instead your bottling kombucha! I found this you tube video that shows how to do it as well as this book I found on amazon that tells how to ferment tea   and with recipes too.

Kombucha is a fermented tea that has been consumed for thousands of years, and its origin is either China or Japan.
 It's rich in beneficial probiotics and  contains antioxidants, that can kill harmful bacteria and helps fight several diseases.
It's made by adding specific strains of bacteria, called a scoby (symbiotic culture of bacteria and yeast), to sugar and black or green tea, then allowed to ferment for 7-10 days.

During this process, bacteria and yeast form a mushroom-like film on the surface of the liquid. This is why kombucha is also known as "mushroom tea."  This blob is a living symbiotic colony of bacteria and yeast, or a SCOBY, and can be used to ferment new kombucha.
The fermentation process produces acetic acid (also found in vinegar) and several other acidic compounds, trace levels of alcohol and gases that make it carbonated    A large amount of probiotic bacteria is also produced during fermentation
Probiotics provide your gut with healthy bacteria. These bacteria can improve many aspects of health, including digestion, inflammation and even weight loss.  For this reason, adding probiotics foods like kombucha to your diet might improve your health in many ways. Green tea is one of the healthiest beverages on the planet.   This is because green tea contains many bio-active compounds, such as polyphenols, which function as powerful antioxidants in the body.
Kombucha made from green tea contains many of the same plant compounds and presumably boasts some of the same benefits Studies show that drinking green tea regularly can increase the number of calories you burn, reduce belly fat, improve cholesterol levels, help with blood sugar control and more.  Studies also show that green tea drinkers have a reduced risk of prostate, breast and colon cancers.
 Kombucha is rich in antioxidants, and studies have shown that it protects rats’ liver from toxicity.
One of the main substances produced during the fermentation of kombucha is acetic acid, which is also abundant in vinegar.
Like the polyphenols in tea, acetic acid is able to kill many potentially harmful microorganisms.
Kombucha made from black or green tea appears to have strong antibacterial properties, particularly against infection-causing bacteria and Candida yeasts.
These antimicrobial effects suppress the growth of undesirable bacteria and yeasts, but they do not affect the beneficial, probiotic bacteria and yeasts involved in kombucha fermentation.
Kombucha has been shown to improve “bad” LDL and “good” HDL cholesterol levels in rats. It may also protect against heart disease.
Type 2 diabetes affects over 300 million people worldwide. It is characterized by high blood sugar levels and insulin resistance.
A study in diabetic rats found that kombucha slowed down the digestion of carbs, which reduced blood sugar levels. It also improved liver and kidney function.
Kombucha made from green tea is likely to be even more beneficial, as green tea itself has been shown to reduce blood sugar levels.
In fact, a review study of almost 300,000 individuals found that green tea drinkers had an 18% lower risk of becoming diabetic (32).
Further human studies are needed to investigate the benefits of kombucha for blood sugar control. Kombucha improved several markers of diabetes in rats, including blood sugar levels.
Cancer is one of the world's leading causes of death. It is characterized by cell mutation and uncontrolled cell growth.
In test-tube studies, kombucha helped prevent the growth and spread of cancerous cells due to its high concentration of tea polyphenols and antioxidants.
Kombucha is expensive and making your own is fun and cost saving.



Health Nuts - How to Brew Kombucha - YouTube
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Dr. Stephanie Seneff discusses one of the most important health issues of our time – glyphosate toxicity. It’s in most non-organic foods and is ruining your health, causing autism, gut dysbiosis, problems detoxing and even cancer.

Learn what you can do to protect your health and how glyphosate may be contributing to your fatigue and health issues.
Tune in to hear all about:
  • How glyphosate causes chronic fatigue, autism, dementia, gut dysbiosis, cancer and more
  • Glyphosate causes mineral deficiencies and oxalates
  • Glyphosates contributes to sulphur sensitivity
  • How glyphosate makes vaccines more toxic
  • How to detox glyphosate
Transcript Click here to view the full transcript for #166 Glyphosate and How to Detox it with Dr. Stephanie Seneff.
Dr. Stephanie Seneff is a Senior Research Scientist at MIT’s Computer Science and Artificial Intelligence Laboratory in Cambridge, Massachusetts. She has a BS degree from MIT in biology and a PhD from MIT in electrical engineering and computer science.

Glyphosate and How to Detox It with Dr. Stephanie Seneff - YouTube
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Biology 101 -- Metabolism is a complex process that has a lot more going on than personal trainers and commercials might have you believe. Let's explore some of its key parts, including vital nutrients -- such as water, vitamins, minerals, carbs, fats, and proteins -- as well as how anabolic reactions build structures and require energy, while catabolic reactions tear things apart and release energy.I hope this crash course helps in making better food choices.

Metabolism & Nutrition, part 1: Crash Course A&P #36 - YouTube
Metabolism & Nutrition, part 2: Crash Course A&P #37 - YouTube
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Copper toxicity is a condition in which copper is retained and begins to build up in the body tissues. Dr. Carl Pfeiffer and other pioneering practitioners first warned of this problem in the 1970's. The circulation and proper utilization of copper in the body requires good functioning of the liver, gall bladder and adrenal glands. If any of those organs are impaired, the body cannot properly excrete and utilize copper. Initially, the copper will build up in the liver, further impairing its ability to excrete copper. As copper retention increases, it will build up in the brain, the joints and the lungs, adversely affecting the structure and function of the tissues.
Copper is a powerful oxidant causing inflammation and free radical damage to the tissues. To avoid these toxic effects, it must be bound to the binding proteins, ceruloplasmin and metallothionine. These proteins can become deficient due to impaired adrenal and liver function which allows free copper to build up. It can have a toxic effect (similar to other heavy metals) on the body and mind and it is a contributor to many chronic illnesses and mental disturbances.
Sources of CopperCopper is common in the diet, particularly in vegetarian diets, and can be found in the water due to copper plumbing. Many multiple vitamins contain relatively high doses of copper. Zinc and manganese deficiencies will also cause copper retention. The hormone estrogen promotes the retention of copper and this is why women are particularly vulnerable to the problem of copper toxicity.
However, prolonged adrenal stress can eventually cause the problem in both men and women. Some children are born with high copper levels as it can be passed through the placenta and the high estrogen of pregnancy can worsen any copper retention the mother has.
Effects of CopperPhysically, the copper build up interferes with proper conversion of thyroid hormone at the cellular level. It also disturbs zinc balance, interfering with adrenal hormone production and this weakens the immune system. The impairment of both thyroid and adrenal gland function causes the most common copper toxicity symptom: fatigue.
It inhibits cortisol (glucocorticoid) production which causes hypoglycemia and increased inflammation, and increases aldosterone (mineral corticoid) production which enhances brain activity and can give a feeling that the mind is racing.


It is stimulating and irritating to the nerves and can lead to headaches including migraines, neuralgia, such as sciatica or trigeminal neuralgia, and other neurological conditions such as epilepsy and tremors. It causes joint pain and arthritis, digestive problems, irritable bowel, overgrowth of candida albicans, breathing difficulties including asthma, and chronic skin problems which can range from acne to psoriasis.
It's relation to estrogen levels makes copper toxicity a common cause of menstrual disorders, uterine fibroids, PMS and hormone imbalances. Copper gives a temporary boost to an exhausted system so cravings for high copper foods such as coffee, chocolate, avocados, shrimp and lobster, soy and fruit are very common.


Copper is a Heavy MetalThe tendency of copper to build up in the body is similar to that of iron. As the danger of excessive iron was not recognized for many years, the problem of copper retention is only now being widely recognized. Both copper and iron must be bound to specific proteins in order to be safely transported through the blood.
Both metals are highly reactive with strong electrical conductivity. This makes them prone to creating free radical activity and damaging many cells when in a free form. This is true for all heavy metals which is why they all eventually contribute to adrenal fatigue. The presence of excess heavy metals, including copper, is a constant source of stress which eventually exhausts our ability to respond properly to stress.
Mineral BalanceThe body has an intricate system of checks and balances which operate through the mineral levels and ratios. If one mineral becomes deficient, another mineral will accumulate and may become excessive.
When sodium and potassium levels go down, calcium and magnesium levels will rise. If copper drops, iron increases. If zinc rises, copper will decrease. If iron rises, chromium levels decrease. The body controls many body functions through the modification of the mineral ratios.


Copper initially raises the sodium level, and the body will retain copper to shore up a dropping sodium level (due to unremitting stress) in order to support mineral corticoid production. Copper is also essential to the final step in energy production in the Krebs cycle, one of the main energy producing processes in the body.


Copper and StressAn accumulation of copper serves a purpose, in the short run, as a defense against stress. As the body loses zinc under stress, sodium increases along with copper. Both of these changes increase oxidative respiration and energy production in the cells. This is a short term defense against stress which we all need. It is only when it becomes chronic that copper toxicity results.
During acute stress, the loss of zinc and magnesium and the retention of copper serve the body, and improve the adrenal response to stress. With chronic, unrelenting stress, or extreme, catastrophic stress--these defenses begin to work against us.


Stress is a normal part of life and is a natural aspect of being productive and vigorous. Accomplishment and creativity always result in some stress. Our bodies were designed to be able to thrive on a certain amount of stress. But if stress is such that you cannot cope, make decisions, concentrate, or get work done, then the stress is excessive and can eventually result in copper toxicity and adrenal fatigue. The adrenal glands become depleted when they do not have the time and nutritional support to recharge.


Stress and Your EmotionsCopper toxicity reduces the ability to cope normally with stress and the inability to respond adequately can provoke many fearful emotions, including anxiety and panic. In many cases, the body over-reacts to nearly any stress rather than under-reacting. This constantly puts the body into a full fight or flight defensive reaction which normally includes the emotions of anger and fear. This is why chronic stress and adrenal fatigue are often associated with anxiety, panic, phobias and compulsions.
Hypoglycemia and blood sugar swings due to adrenal fatigue are a well known cause of many mental and physical symptoms such as depression, irritability, mood swings, poor concentration, poor memory, dizziness, fatigue and sleepiness.
Copper/zinc ImbalanceCopper toxicity is particularly disturbing to the body and mind because of its effect on zinc. Zinc is an extremely important nutrient and a deficiency has a wide range of consequences. Zinc is used up rapidly under stress, and when stimulants such as coffee, alcohol and sugar are used.
Zinc is a sedative, calming mineral for the brain. When copper becomes high, zinc levels drop, increasing the stimulating effect of copper on the mental functions. GABA, an inhibitory, calming neurotransmitter, is zinc dependent.


The ideal ratio of copper to zinc is 1:8 in favor of zinc. Zinc is usually accompanied by copper in the diet. The only common food that has high zinc without high copper is meat and to a lesser degree, eggs.
Copper is a common element in many foods and so being able to excrete it normally and regularly is a more important concern. A zinc deficiency will impair the ability to excrete copper. Copper deficiency usually only occurs with severe malnourishment as in anorexia.


Zinc Is Essential For Protein SynthesisZinc is essential for the body to synthesize protein so a deficiency often is revealed in the condition of the protein structures of the body such as the skin and nails. Stretch marks are always a sign of low zinc as the skin depends on zinc for its normal integrity. A deficiency allows the skin to tear just below the surface and produces scars.
Zinc is used up rapidly when tissue healing demands it after injury, or surgery. Low zinc impairs wound healing due to impaired protein synthesis. Teenagers are vulnerable to zinc deficiency due to their rapid growth.


Low zinc impairs the immune system. Zinc can destroy some viruses on contact and a deficiency can increase susceptibility to viruses. The adrenal glands are essential for good immune function and zinc is essential for the production of the adrenal cortical hormones aldosterone and cortisol.


Zinc and AppetiteZinc is required for a normal appetite and normal smell and taste. Poor appetite, especially in the morning with some light morning nausea, is typical when zinc is low. Copper/zinc imbalance is common in teenage girls and if it becomes severe enough anorexia can result.
Protein intolerance is also common when copper is high and zinc is low. An inability to tolerate certain protein foods, particularly red meat or possibly any meat or eggs, is typical in more severe cases of copper/zinc imbalance. The tendency to adopt a vegetarian diet in this case worsens the condition due to the low zinc content of the diet.
Copper and the MindCopper toxicity has a powerful effect on the mind. Depending on the severity of the toxicity and the susceptibility of the person, copper can affect the mind moderately or very severely. The milder effects are initially positive because it is activating and stimulating to the mind and can increase creativity and productivity. Many copper toxic people are very creative. The problems begin as the toxicity continues to build up, and it becomes more and more exhausting to the body while being stimulating to the mind.
It becomes a process of an exhausted body trying to keep up with an over active mind. The mind makes many plans which cannot be realized and frustration starts to become a dominant state. This can lead to depression and/or anxiety as this conflict continues to worsen. Short attention span is another result of the over-stimulation.
At first, switching back and forth between them is common as the stimulating effect alternates with the fatiguing effect. This can create a pseudo-bipolar condition. But over time, fatigue and depression will win out. Copper can also contribute to the development of schizophrenia and autism in susceptible people.
Although there is a very strong physical aspect to mental and emotional states, they are also strongly influenced by our own thoughts, beliefs, and habits. Part of what can happen as we become healthier, is that a certain kind of "lid" is removed from our emotions and minds. We may have relied on fairly strong emotional suppression which can be achieved by creating certain biochemical imbalances in an unconscious manner.


When we are specifically undoing those imbalances through the application of a targeted Nutritional Balancing program, we may find that we have to work on some underlying issues that this has allowed us to avoid in the past. The imbalances were acting as a kind of coping mechanism which we had come to rely on. It is almost like learning to live without cigarettes or alcohol if those were used as problems solvers in the past.
Although certain emotional aspects will very much improve as the copper clears out (for me this was noticeable after about six months), in other ways, we will be faced with issues we have been avoiding. Eliminating copper toxicity often results in an increase in awareness. As these aspects of our life and self become more visible, we may need to do some soul searching and habit breaking in regards to our beliefs and reactions to life.


Copper Is A StimulantCopper stimulates the production of the activating neurotransmitters epinephrine, nor-epinephrine, dopamine and serotonin. Anxiety, racing mind and insomnia are all signs of the over-production of these neurotransmitters. Copper also increases the electrical potential of the neuron, possibly due to the enhancement of the movement of sodium.
Pfeiffer and Goldstein (1984) demonstrated that brain waves exhibit an equivalent central nervous system stimulation from either 5 mg. of copper or 5 mg. of Dexedrine. The over stimulation caused by copper is equivalent to that induced by amphetamine usage. Amphetamines can produce a temporary psychosis from prolonged use.


As the liver becomes overloaded with copper, the body begins storing the excess in other organs, particularly the brain. Copper stimulates the di-encephalon, which is the emotional brain. Zinc stimulates the cortex or new brain which tends to calm the emotions.
Stress promotes the loss of zinc into the urine and the rise of copper leading to the over-activation of the emotions and exaggerated emotional responses, both high and low. The emotional state can alternate depending on the amount of stress, current diet, medications and hormonal changes. The swings can mimic bipolar conditions or be a part of premenstrual emotional problems.


Methylation and The MindNumerous studies have shown that about one half to two-thirds of schizophrenics have high levels of copper along with low levels of zinc and manganese especially during acute phases. Carl Pfeiffer, Ph.D., M.D. studied over 20,000 schizophrenic and mentally ill patients over many years and found that high copper patients are also low in histamine.
The copper-containing enzymes, histaminase and ceruloplasmin, regulate histamine. Elevated copper increases the levels of these enzymes, promoting histamine breakdown. The low histamine levels, allow copper to continue to rise. Histamine is an essential protein metabolite (a product of metabolism) found in all body tissues. In the brain, it acts as a neurotransmitter. Low histamine is a marker for high copper.
Histamine and MethylHistamine levels are also related to the methylation cycle, a metabolic pathway that is essential for detoxification and for controlling free radical activity. Methyl and histamine compete with each other.
When histamine is high, it is a sign of under-methylation, and when histamine is low, there is over-methylation. With too much methyl, the body will overproduce dopamine, norepinephine and serotonin (the activating neurotransmitters), with too little methyl, the neurotransmitter levels are too low.
Methyl Controls Many Body ProcessesMethyl is one of the more common organic chemicals in the body. Methyl groups (-CH3)are present in most enzymes and proteins. The methylation cycle is the process by which methyl groups are added to a compound. When a larger biochemical is methylated, it's structure and function change.
SAMe (S-adenosylmethionine) is the body's primary methyl donor. It methylates neurotransmitters, neurohormones (such as melatonin), proteins, membrane phospholipids (which form the cell membrane), the myelin sheath around the nerves and creatine (used in energy transfer).


If methylation is impaired, then neurotransmitter function, protein and cell membrane structure and function, fatty acid metabolism, allergic (histamine) responses, myelination of the nerves, and cellular energy transfer are all impaired. Methyl groups control genetic expression during fetal development and throughout life. A methyl group can attach to specific DNA sequences and turn off that gene. When the methyl group is removed, the gene is turned on.


The Methylation CycleWhen SAMe donates a methyl group (-CH3), it becomes SAH (S-adenosylhomocysteine) and then homocysteine. Methionine is the next most important source of methyl groups and it can be made from homocysteine by accepting a methyl group from the folic acid cycle.
Methylation requires a constant source of folic acid and vitamin B-12 (methylcobalamin). Low B-12 impairs the enzyme that converts homocysteine back into methionine (methionine synthase - MS).
Methylation and GlutathioneOxidative stress (free radical activity) can also inhibit MS, so certain toxins such as mercury will disturb the methylation cycle. When a heavy toxic burden is present in the body, homocysteine will be shunted to the detoxification and antioxidant pathways to produce metallothionein and glutathione, rather than to the methylation cycle.
Homocysteine will be converted to cysteine, taurine or used as a source of sulfate to promote bile formation and heavy metal excretion. Cysteine is used in the formation of metallothionein and of glutathione, the most powerful antioxidant and an essential substance for heavy metal detoxification.
Methyl and PsychosisParanoid schizophrenia is associated with over-methylation, detected by low histamine, and high copper. The main symptoms in histapenic (low histamine) schizophrenics are auditory hallucinations along with suicidal depression, paranoia, religiosity and sleep problems. Supplements which reduce methyl include folic acid, vitamin B12, and vitamin B3. The copper/zinc imbalance must also be improved in order to reduce the destruction of histamine.
Impaired methylation is also seen in autism. In studies measuring the components of the methylation cycle , all of the methylation and transsulferation markers were much lower in autistic children. The nutritional supplements which often improve autistic symptoms support the normal function of these pathways. These include folinic acid, DMG, TMG, methylcobalamin (B12), zinc, B6 or P5P, glutathione, cysteine, and sulfate.
MetallothioneinMany people with over-methylation also have a metal metabolism problem related to under functioning of metallothionein. Metallothionein is involved in many functions of the body, including immunity, brain and gastrointestinal tract maturation, and the regulation of metals.
Metallothionein is essential for maintenance of the proper ratio of copper to zinc. So much so, that a zinc/copper imbalance is the indicator for a metallothionein malfunction. The malfunction could be due to a genetic weakness but may also be primarily induced by nutritional deficiencies and imbalances. The primary nutrient needed in the formation of metallothionein is zinc.


Metallothionein is crucial to the body in regulating and coping with toxic metals. It envelopes metals such as mercury, lead and cadmium, binding with them and carrying them out of the body. Mercury or lead in the gut require metallothionein in order to disable the toxic substance.


Metallothionein and Gluten/Dairy IntoleranceWithout the metallothionein, the toxic metals are most likely to interact with chemicals called sulfhydral groups. A combination of sulphur and hydrogen, these groups have tremendous power to bind to mercury, lead, and cadmium but especially mercury.
Among the sulfhydral groups in the intestines are the enzymes that break down casein and gluten. Toxic metals and low zinc interfere with the enzyme’s function giving rise to gluten intolerance to grains such as wheat, rye, barley and oats, and to dairy intolerance. Gluten and casein intolerance are very common in conditions ranging from chronic fatigue and asthma to bipolar disorder, autism and schizophrenia.
Metallothionein and AutismHigh copper, low zinc and signs of low metallothionein function with elevated levels of lead, cadmium, arsenic, antimony, and/or mercury occur in nearly every autisic patient tested.
At the Pfeiffer Treatment Center all the symptoms and conditions relating to autism have been found to correlate to the signs of a metallothionein deficiency. 

Toxic Metals
PyroluriaPyroluria is characterized by excess krytopyrrole in the urine. Kryptopyrrole binds with B-6 and zinc and is excreted in the urine resulting in B-6 and zinc depletion. This condition was discovered separately by Doctors Carl Pfeiffer and Abram Hoffer.
Studies have shown that 11% of the general population has some degree of pyroluria but 52% of schizophrenics and 42% of psychiatric patients are pyroluric. It is a hereditary condition and will show up to various degrees of severity in family members. Alcoholic families are very prone to have this condition as 40% of alcoholics are pyroluric.


Other family tendencies are cluster headaches and migraines, depression, fatigue which can become chronic fatigue, sensitivity to cold, anemia, nausea, lack of dream recall, and suicides or suicidal depression.


Onset of PyroluriaThe initial onset of a more severe pyroluric episode usually occurs during the teenage years often in response to stress. The high demand for zinc in the teenager is often a trigger for the onset of symptoms, but some symptoms will be seen from early childhood.
Stress intolerance is often seen throughout life as they react severely to stressful events such as love affairs, moving, going to college, joining the military or injuries and trauma.
Conditions Associated With Pyroluria:
  • poor appetite
  • motion sickness
  • morning nausea
  • blood sugar problems
  • glucose intolerance
  • sore low back
  • upper left pain in the ribs
  • rib pain when running
  • drug and/or alcohol intolerance
  • very chronic constipation
  • crowded upper front teeth
  • poor collagen synthesis affecting joint development
  • tingling sensations, tremors, and cramps in the limbs
  • convulsive seizures
  • neuralgia
  • late onset of puberty
  • pale skin with little tanning
  • prematurely grey hair
  • pale, thin fingernails
  • low stress tolerance, social withdrawal
  • teenage amnesia, delinquency
  • sweet, fruity acetone breath and body odor
  • cold hands and feet, unexplained chills and fever
  • vulnerable to infection, flu
  • skin problems: stretch marks, acne, eczema, psoriasis
  • poor wound healing
  • dis-perceptions, delusions
  • paranoia
  • periodic loss of contact with reality
  • easily irritated, can become violent
  • easily fatigued, can be apathetic at times
  • great drive and creativity earlier in life in spite of symptoms
Pyroluria and GlutathioneVitamin B-6 or P-5-P, cysteine and zinc are rate limiting nutrients for the formation of glutathione the main anti-oxidant. Glutathione has many essential functions including maintaining mitochondrial integrity and ATP production (essential for energy).
It supports T-cells and protects against viruses, maintains the structural integrity of the gut and is the primary means of detoxifying and eliminating heavy metals and other toxins. It also maintains vitamin C and vitamin E in their active forms. The impairment of glutathione production due to the severe B-6 and zinc loss in pyroluria, accounts for a great many of the problems associated with it.
Pyroluria and StressPyroluria is worsened by stress as the production of kryptopyrroles can double under stress. Therefore the condition can become relatively mild if stress is minimized. Many pyrolurics instinctively avoid stress and have often developed certain dietary approaches and supplement usages that do help the problem.
But under stress, the need for B-6 and zinc can become much higher than would normally be used, up to 2000 mg per day of B-6 and 90 - 120 mg zinc because they are being lost in the urine at a very high rate. Taking higher doses prior to stressful events can prevent an episode. The low zinc naturally results in a high copper condition and the long list of problems seen in this condition is in many ways a list of the effects of low B-6, low zinc and high copper.


Non-pyrolurics may have many of these conditions as it is not difficult to develop a B-6 and zinc deficiency with high copper due to chronic stress. The non-pyroluric will not need the very high doses of these nutrients in order to improve.


Slow OxidationThe effect of high copper on the adrenal and thyroid glands reduces the metabolism and creates a state of slow oxidation in the body. Oxidation Type is a concept developed by Dr. George Watson, a researcher at UCLA.
Oxidation means to burn or mix with oxygen. Those who burn food at a slower than ideal rate are slow oxidizers. Oxidation rate is mainly a reflection of thyroid and adrenal activity. Copper slows both glands down.
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The Truth about Magnesium & Copper: Food Industry Secrets- Thomas DeLauer - YouTube
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With hints of garlic and lemon, this hummus recipe is full of Mediterranean flavor, and it’s also high in several essential nutrients, such as healthy fats, calcium, and vitamin C. The addition of bone broth also adds type II collagen, a beneficial protein found only in bones and connective tissue, which is known for improving gut, skin, and joint health. Bone Broth is great to sip by itself too!
Yield: 2
Ingredients:
  • 1/2 cup Kettle & Fire beef bone broth
  • 1 can garbanzo beans
  • ¼ cup tahini
  • 1 garlic clove minced
  • ¼ cup lemon juice freshly squeezed
  • 1 teaspoon cumin
  • 1 teaspoon paprika
  • 1 teaspoon salt
  • ¼ cup olive oil
Instructions:
  1. In a medium pot over medium heat, add beef bone broth and garbanzo beans.
  2. Bring to a boil and let simmer until garbanzo beans have soaked up almost all of the broth, about 10 minutes.
  3. Using a food processor, add garbanzo beans, remaining broth from the pot and the rest of the ingredients excluding the olive oil.
  4. Process until smooth, adding olive oil slowly while processing.
  5. Serve with olive oil, paprika, and roasted garbanzo beans to garnish.
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      We have always been told that too much salt is bad for us.  It's correct if your talking about table salt. Table salt is very heavily processed, and commercial table salt is typically 97.5 percent to 99.9 percent sodium chloride. With most table salts, you’re only left with one mineral (sodium), some added iodine and most often an unhealthy-hazardous anti-clumping agent. Many commercial table salts also undergo a bleaching process and contain aluminum derivatives and other terrible ingredients known to be highly toxic to human health.

The Pink Himalayan sea salt contains over 84 minerals and trace elements, including calcium, magnesium, potassium, copper and iron and it comes from comes from the Punjab region of Pakistan about 190 miles from the Himalayas. This region has one of the richest salt fields in the entire world, and they are very, very old. I’m talking Precambrian Age or over 4 billion years ago when planet Earth first formed!  With a history dating back to Earth’s creation, Himalayan salt is believed to be composed of dried  remnants of the original, primal sea.


Top 5 Benefits of Pink Himalayan Salt

1. Improves Respiratory Problems
According to the Lung Institute, salt is antibacterial, anti-inflammatory, loosens excessive mucus and speeds up mucus clearance, removes pathogens in the air like pollen, and decreases IgE level (immune system oversensitivity).
There is actually a term for this type of natural treatment. It’s called halotherapy. Derived from the Greek word for salt, “halos,” halotherapy or salt therapy is the inhalation of micronized dry salt within a chamber that mimics a salt cave. Studies have shown halotherapy to be a highly effective drug-free part of successfully treating chronic bronchitis.

2. Balances Body’s pH
Pink Himalayan sea salt’s rich mineral content can help balance your body’s pH levels. You may think this is no big deal, but when your pH has a healthy acid-to-alkaline ratio, it makes a huge difference in your overall health. A proper pH helps foster your immunity and encourage good digestion. Since pink Himalayan salt contains sodium as well as other electrolytes, it has a direct effect on the pH of your blood.

3. Natural Digestive Aid
You can use pink Himalayan salt to make your own sole, a saturated solution containing purified water and Himalayan salt. Sole is  a salt water flush recipe, in which you can use pink Himalayan salt to help you obtain all the many possible benefits of a salt water flush. I add a pinch of himalayan salt to my water bottle to replenish minerals that were taken away during osmosis.
According to natural health practitioners like Dr. Mark Sircus, an acupuncturist and doctor, a dose of sole each day can really help the digestive system in major ways. He says that “daily use of sole is believed to stimulate the peristalsis of the digestive organs, balance the stomach acid, support the production of digestive fluids in the liver and pancreas, regulate the metabolism and harmonize the acid-alkaline balance.”

4. Air Purifier
When pink Himalayan salt is used to create a lamp, it just may provide your home or office with cleaner air. One of the main Himalayan salt lamp benefits is its supposed ability clean the air. How? By its inherent nature as a salt, the lamp (which is a block of pure pink Himalayan salt) attracts water vapor to it as well as air pollutants. The water vapor evaporates due the lamp’s heat, but the dust and allergens remain in the salt instead of getting into your body.

5. Better Sleep Inducer
Himalayan sea salt is said to help encourage better, more restful sleep due to its high mineral content. It may be hard to believe, but eating enough salt in your diet daily is actually key to a good night’s rest as a natural sleep aid.
Research way back in 1989 showed that low-sodium diets can cause disturbed and irregular sleep patterns. The study was small, but the results were very interesting. Subjects on low-sodium diets (around 500 milligrams a day) woke up during the night almost twice as often and got about 10 percent less sleep than those on a normal diet (2,000 milligrams of sodium a day). A high-sodium diet (5,000 milligrams a day) led to even longer sleep than the normal diet with fewer nighttime wakings.

There are many more health benefits to himalayan salt just go to  Dr. Axe website for more information.
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Do you know what osteoporosis ACTUALLY is?
Do you think it’s calcium loss?
Needing to drink more milk?
Hormones NOT in proper balance?
‘Just in your genes’?

Actually no… “It is caused by an imbalance in bone remodeling, where bone reabsorption by osteoclasts exceeds bone formation by osteoblasts.” (Christenson RH. 1997 and also supported by Zarjou A et al, 2010)

Unlike the ‘Stop autoimmunity’ website assertion that ‘there’s a limited time that we can increase our bone mass’, we are continuously regenerating new bone. The bones we grow as children and young adults do not suddenly stop cellular growth and repair when we hit our 30s and 40s. Beyond continual repair and regeneration of bone, the bone marrow provides us with ongoing supplies of red blood cells and immune cells.

There’s a Yamasaki K, Hagiwara H. 2009 study which is titled “Excess iron inhibits osteoblast metabolism” – well, that’s fairly self-explanatory isn’t it? They talk about how their results give an indication that iron overload might give rise to osteoporosis by inhibiting osteoblast proliferation and differentiation.

What one of the studies presented below raises, is that if we are struggling to make bone marrow, then perhaps our capacity to make new blood cells may be hindered. What do you think could be the underlying reason for this hindrance?

First, I want you to start thinking about  how excess, unbound Iron FUELS the aging process. What happens to our IRON levels as we get to around 40?
If we look at Figure 1 (slightly adjusted from the ‘Stop autoimmunity’ original source), we notice women’s bone density “suddenly” appears to decrease from the 40-50 age range.
What do we know happens in the 40’s and 50’s for women?   Menopause.
Osteoporosis and menopause – what’s the link?
What does this mean in the context of metabolism in the body? Suddenly women are accruing iron, not bleeding every month… the iron building up in their body is causing changes in the osteoblasts which prevents them from maintaining density. What does excess unbound iron cause in the body?   Oxidative Stress.

Winding back a bit further, Reactive Oxidative Species (ROS) such as superoxide and that pesky ‘oxidative problem child’ H2O2 (Hydrogen Peroxide) SHOULD be neutralized by our natural antioxidant enzyme systems,  however, in mineral dysregulated bodies, which are HIGH in unbound iron, LOW in bioavailable copper and magnesium, and with LITTLE antioxidant support in the body (let’s think of our ever-busy Ferroxidase, and Superoxide Dismutase (SOD), if we do not have enough of the components in our antioxidant systems, we cannot neutralize these “Accidents,” that are called “Oxidants” that are ALSO called, Reactive Oxidative Species.

Cellular changes start to happen, let’s say… osteoblasts cannot keep up with recycling of the bones, and our Bones get weaker and less able to stay in balance.
What should make you all uneasy about this is that there are FEW, IF ANY, articles that are published which note the changes & challenges in Iron metabolism and its KNOWN & WELL CHRONICLED impact on bone health and bone replacement – WHY is this not ROUTINE? WHY is this not shared or tested for?
How many family members/friends have had their Iron investigated when also investigating osteoporosis?

There is overwhelming evidence in the research presented in Jia et al, 2012, “Ferric Ion Could Facilitate Osteoclast Differentiation and Bone Resorption through the Production of Reactive Oxygen Species”.
They present strong evidence around the diagnosis of Osteoporosis being clinically PROVEN to be from oxidative stress in the Bone Recycling Program. More papers are listed in the reference list below.

↑ Iron = ↑ Oxidative stress = ↓ OsteoBlast regrowth = ↓ Bone Density = ↑ Chance for Osteopenia/Osteoporosis



Osteoporosis and Estrogen/Hormones – what’s the link?

We already know from several past iron toxicity posts that Hormones are ruled by enzymes that RELY on minerals for activation in the body – so, if our adrenals aren’t working effectively (STRESS anyone?)… the body goes into a ‘backup mode’ and changes happen in the hormones (Estrogen Dominance so often rolls on in! And what is NOW known is that the Estrogen is NOT LOW, but simply NOT BIOAVAILABLE)

And what’s underlying these habitual, and all-too-common hormonal changes? Once again, Excess, Unbound iron!
There is discussion in the paper by Jian J, Pelle E, Huang X., 2009, about the involvement of hormones, including Estrogen, in osteoporosis.
“……In addition to Estrogen deficiency, abnormally high iron is a key cause of postmenopausal osteoporosis.”

So, are you telling me that if we have women experiencing Estrogen deficiency, then abnormally high iron is a key player in osteoporosis as a result? WHAT?! Hormones are related to bone density?

I would suggest considering the other ‘book end’ of Estrogen Dominance having an involvement there, too – as has been talked about extensively in past iron toxicity posts/discussions in MAG. Instead of obviously HIGH Iron by the definitions commonly used, we know that Iron stores are building, while the amount of ‘available’ & ‘usable’ Iron is dropping……. bioavailable copper and magnesium are bottoming out, and the true Iron levels are not obvious particularly because of the testing generally done by conventionally-trained practitioners.

Underlying the Estrogen Dominance – there is still excess, unbound Iron wreaking havoc in the woman’s body, preventing bone regeneration and seeing bone density dropping rapidly, especially when women become post-menopausal.

(which leads to ↑ Iron via supplementation in allopathic and other conventional practitioner circles and
↑ estrogen, and ↑ risk for Osteoporosis!)

More iron loading, more Estrogen Dominance problems, more drugs and synthetic hormones added to their body to “fix” the problem (i.e. “treat the Seats” of symptoms) and the sicker female folks get…

Huo Y et al, 2012 comment within their article “Excess iron is associated with various diseases including osteopenia and osteoporosis, which are closely related to the alternation of the endogenous estrogen level”. They talked about creating a mouse model by removing ovaries and then monitoring hemoglobin and serum iron (both decreased)… yet the Iron level in the liver and spleen tissue increased. Hepcidin was elevated in these mice too.

When was the last time your doctor tested your hepcidin levels If they were worried about anemia?
Stick with me here a bit longer here… if Estrogen contributes to iron homeostasis, and we have a STRESSED OUT population of women who have been misled and misfed information about what is REALLY in their food, what is in their birth control pills, they have led a low-fat (i.e. LOW Retinol-A, LOW-bioavailable copper) diet, eaten less and less of the foods their parents (Mothers) and grandparents (grand-Mothers) ate…potentially more laden with sprays and processed food than previous generations…

You mean to tell me that when post-menopausal, there are signs that it’s likely more Iron will be stored via Hepcidin in the organs, while the amount of Iron in their Hemoglobin AND Serum drop……. WHAT?! Does this sound familiar to any of you reading along?

Not to mention that we have a population where more and more women are having symptoms of/or labels applied of estrogen dominance – SO many either being thrown into surgical menopause (often not keeping ovaries too!) or due to other imbalances…

Now let’s build our list…
↑ Excess Iron = ↑ Oxidative stress = ↓ osteoblast regrowth = less bone density
↑ Excess, unbound iron = ↑ Estrogen = ↑ Iron stored into the Liver via Hepcidin + ↓ levels of Hemoglobin + Serum Fe

Osteoporosis and retinol – how can it help?
I have recently discussed the critical importance of Retinol in our bodies to help get the body moving Iron where it needs to go, getting our Bioavailable Copper increased, and so much more.
We know that new blood cells are made within the bone marrow (or the cascade of cell creation is started there at a minimum). We are learning today that when there is high oxidative stress as iron increases in the body, that the regeneration of bone cells (osteoblast regeneration) is reduced.
What else do the osteoblasts need to carry out the repair and regeneration?
Three KEY Ingredients:
1. Retinol-A  (Vitamin A).
2. Bioavailable copper.
3. Magnesium.

Bloem, 1995 stated that ‘repletion with vitamin A was followed by regeneration of the bone marrow, disappearance of the Hemosiderin from the spleen and liver, and erythroblastic activity.’ That’s a BLOCKBUSTER SHIFT in the dynamics of bone activity,,,
We have established above that there’s more Iron getting stored into many women’s livers and spleens from hormone imbalances, that with increased oxidative stress, there’s less osteoblast regrowth in the bones and less bone density… and now we are saying that retinol (vitamin A) intake from FOOD causes regeneration of bone marrow, reduction in the loading of iron in the spleen and liver, and increased cell production?
NO WAY?!?
What’s compounding these changes? “STRESSORS!” (from our VERY stressful modern day life, from the chemicals put into our bodies, food, inherited from our mothers/ grandmothers, from blue light bombardment, from expectations of mothers to be EVERYTHING to EVERYONE 24/7……..from excess, unbound IRON….. the never-ending process of creating Oxidative Stress keeps chugging it out!…)

Back to our list…
↑ Excess, unbound Iron = ↑ Oxidative stress = ↓ Osteoblast regrowth = LESS bone density
↑ Excess iron = ↑ Estrogen = ↑ more Iron stored into the Liver via Hepcidin + ↓ Hemoglobin + Serum Fe
↑ Retinol-A (via food repletion) = ↑ bone marrow regeneration = ↑ Osteoblasts (maintain bone density) + ↑ new blood cells = ↑ Ferroxidase activity = ↓ Excess, unbound iron = ↓ Oxidative Stress

Vitamin D, zinc and calcium supplementation – why aren’t these critical to bone strength as we keep getting told?
We are already starting to see a picture on how come the RCP (Root Cause Protocol) ties in with reducing the chances of osteoporosis… reduce excess unbound iron, decrease oxidative stress via adrenal support and magnesium, increase bioavailable copper and retinol through food/whole food supplements, and we have our bases covered for the TRUE osteoporosis risk factors.

SO how about the Vitamin D (Hormone-D!), K2, zinc and calcium side of things?
  •  We get K2, zinc and calcium from eating an ancestral diet which is as wide and varied as possible.
  • We get Hormone-D from sunlight and foods such as eggs and cod liver oil (both great sources of retinol – who would have thought??).
  • Calcium carbonate supplements (most commonly suggested) require 12 steps to metabolize them into a form we can actually use. Other than many of the population not having the energy/mineral reserves to deal with that, many of us are going to grind to a halt (think cement = calcium) if calcium is supplemented from anything except food
  • Supplemental Hormone D kills retinol/retinoic acid in our liver, eyes  and elsewhere in the body, preventing it from being able to facilitate cellular regeneration, repair and renewal…… leading to a WEAKENING in bone strength and repair.
  •  Excess hepatic iron disrupts the 25 (OH) enzyme (also mag dependent) – if we have excess iron in our liver….. and we don’t have enough magnesium…. we can’t carry out the transfer of Hormone D within the body – so it’ll test “low”.
  • What’s the biggest reason for insufficient zinc in the body?  EXCESS unbound iron…
  • DID YOU KNOW: Magnesium from food and suggested supplemental sources helps the calcium to go where it’s needed?
We need bioavailable copper (Evans et al, 1970) and retinol to synthesize ceruloplasmin – And it turns out that Retinol-A is ABSOLUTELY critical to loading that ^^^^ Copper to ensure Ferroxidase (FOX) enzyme function (Barber & Cousins, 1987)
If we have INsufficient Retinol-A, and a LACK of Magnesium and a LACK of Bio-available Copper, what happens? We don’t have enough ferroxidase function, and we are faced with Iron that is DYSREGULATED and prone to ACT OUT.

What else happens when we don’t have enough ferroxidase function?
We build up excess stored iron, yet apparent low blood Iron (because the body wants to protect us from the massive oxidative stress that HIGH or HIDING Iron in the blood represents)… our adrenals get stressed out… we start to get any number of metabolic “conditions” kicking in – hormonal imbalances, autoimmune conditions, diabetes, arthritis, depression, Alzheimer’s… our doctors spin us into a panic and dish out More Iron, Vitamin-D and any number of other medications which ONLY compound & confuse these conditions!…

Now the way the RCP (Root Cause Protocol) looks at these things is dramatically different.
Look at our EXPANDED list now!

↑ excess Iron = ↑ Oxidative Stress = ↓ Osteoblast regrowth = LESS bone density
↑ excess Iron = ↑ Estrogen = ↑ more Iron stored into the Liver via Hepcidin + ↓ Hemoglobin + Serum Fe
↑ Retinol (via food repletion) = ↑ Bone Marrow Regeneration = ↑ Osteoblasts (maintain bone density) + ↑ NEW blood cells = ↑ Ferroxidase enzyme function = ↓ Excess, unbound iron = ↓ Oxidative Stress
↑ Magnesium + Bioavailable Copper + Retinol-A = ↓ Oxidative Stress including ↓ Excess, unbound Iron = less chance of osteoporosis/osteopenia (AND the added bonus that Hormone-D will stabilize, too,
in general!)

What does all this REALLY MEAN? Just tell me HOW to reverse this osteoporosis risk……
The research behind the RCP (Root Cause Protocol) has always been encouraging the consumption of whole foods, to obtain whole food vitamin c (to help with bioavailable copper), magnesium and adrenal support (to reduce stress on the body and provide important components for making Mg-ATP (energy)) and retinol (vitamin A)

The research shared today is emphasizing that this is the right path, and that if you want strong bones, low risks of fractures, and to reduce the chance of getting osteoporosis. DO THE PROTOCOL!
  •  Reduce your oxidative stress (from food, physical/mental stress, get plenty of sleep, etc).
  •  Increase your retinol-A, Bioavailable Copper and Magnesium to give you more energy, reduce inflammation and give your body a chance to heal itself
  • Release stresses of the past and emotions which may be holding you back from progressing.
  • Reduce your iron load (when ready – support your body before donating blood!)
RCP = ↓ oxidative stress + ↑ via Bioavailable Bopper, Mag, Retinol-A = ↓ Excess, unbound Iron = ↓ chance for osteoporosis AND better mineral flow throughout the body AS WELL AS ↑ positive health outcomes (= DEC ↓ “Stress!”)

Posted on May 13, 2018 by Morley Robbins
References within or relevant to Iron Toxicity Post #70

Christenson RH. 1997. Biochemical markers of bone metabolism: an overview. Clin Biochem 30:573–593. www.ncbi.nlm.nih.gov/pubmed/9455610
Zarjou A et al, 2010, Ferritin ferroxidase activity: a potent inhibitor of osteogenesis. (www.ncbi.nlm.nih.gov/pubmed/19821764 )
Weinberg ED, 2009-July, Iron Loading in humans: a risk factor for enhanced mortality & morbidity www.researchgate.net/…/232033197_Iron_loading_in_hu…
Weinberg ED, 2008, “Role of Iron in Osteoporosis” (Abstract ONLY)
www.ncbi.nlm.nih.gov/pubmed/19337160
Jia P et al, 2012, “Ferric Iron Could Facilitate Osteoclast Differentiation & Bone Resorption thru ROS”
onlinelibrary.wiley.com/doi/pdf/10.1002/jor.22133
Yamasaki K, Hagiwara H. 2009, Excess iron inhibits osteoblast metabolism, www.ncbi.nlm.nih.gov/pubmed/19735707
Jian J et al, 2009-Dec, “Iron & Menopause: Does Inc Iron Affect the Health of Postmenopausal Women?”
www.ncbi.nlm.nih.gov/pmc/articles/PMC2821138/
Cervellati C et al, 2014 “Oxidative Stress and Bone Resorption Interplay as a Possible Trigger for Postmenopausal Osteoporosis”
www.ncbi.nlm.nih.gov/pmc/articles/PMC3913453/
Rossi F et al, 2014-Dec, “Iron overload causes osteoporosis in thalassemia major patients through interaction with transient receptor potential vanilloid type 1 (TRPV1) channels”
www.ncbi.nlm.nih.gov/pmc/articles/PMC4258755/

Xiao W et al, 2015-Sept, “Iron overload increases osteoclastogenesis and aggravates the effects of ovariectomy on bone mass”
joe.endocrinology-journals.org/content/226/3/121.long
Cervellati C et al, 2014 “Oxidative Stress and Bone Resorption Interplay as a Possible Trigger for Postmenopausal Osteoporosis”
www.ncbi.nlm.nih.gov/pmc/articles/PMC3913453/
Jian J, Pelle E, Huang X. 2009. Iron and menopause: does increased iron affect the health of postmenopausal women? Antioxid Redox Signal 11:2939–2943.
Huo Y et al, 2012, Estrogen Regulates Iron Homeostasis thru Hepatic Hepcidin via ERE (Estrogen)
pdfs.semanticscholar.org/…/d01b60965935df4051230b8a…
Barber EF & Cousins RJ, 1987, Induction of Cp Synthesis by Retinoic Acid in Rats–Inf of Dietary Copper & Retinoic Acid_JrlNutrition www.ncbi.nlm.nih.gov/m/pubmed/3655940/
Guggenbuhl P, Deugnier Y, Boisdet JF, et al. 2005, Bone mineral density in men with genetic hemochromatosis and HFE gene mutation. Osteoporos Int 16:1809–1814 (www.ncbi.nlm.nih.gov/pubmed/15928800)
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