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Summary of Research:

Scientists wanted to develop a polio vaccine which requires only one injection to better prevent the disease in developing countries.
Key terms
+ Polio
+ Vaccine
+ Immunity

Scientific Methods
+ Representative sampling
+ Proxy data

Reading level
+ High school, upper level
+ High school, lower level
+ Middle school

IB Biology Topics and Options (from International Baccalaureate) 
Topic 2. Molecular Biology: 2.4 Proteins
Topic 6. Human Physiology: 6.3 Defense against Infectious Disease
Topic 11. Animal Physiology: 11.1 Antibody Production and Vaccination
Option B. Biotechnology and Bioinformatics: B.4 Medicine

Teacher's Resources
+ Adapted scientific article 
+ Student assessment questions with teacher's key
+ Original scientific paper from PNAS
+ Opening videos
polio_article.pdf
File Size: 674 kb
File Type: pdf
Download File
polio_key.pdf
File Size: 79 kb
File Type: pdf
Download File
polio_original.pdf
File Size: 2039 kb
File Type: pdf
Download File
WHO: Polio Eradication - Reaching Every Last Child - YouTube
WHO: Polio Eradication - Reaching Every Last Child
Duration: 4min
Poliomyelitis - causes, symptoms, diagnosis, treatment, pathology - YouTube
What is polio?
Duration 10min
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Summary of Research:

Scientists wanted to identify the individual termites who are the most active during the start and expansion of tunnel construction.


Key terms
+ Termite
+ Insect
+ Animal behavior
+ Tunneling

Scientific Methods
+ Representative sampling
+ Data extrapolation
+ Animal behavior analysis

Reading Level
+ High school, lower level
+ Middle school

AP Environmental Science topics (from the College Board)
III. Population: A. Population Biology Concepts

Teacher's Resources
+ Adapted scientific article
+ Student assessment questions with teacher's key
+ Opening video
termites_article.pdf
File Size: 1563 kb
File Type: pdf
Download File
termites_key.pdf
File Size: 108 kb
File Type: pdf
Download File
My subterranean termite colony 1 year - YouTube
Subterranean termite colony
Duration: 2min
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Summary of Research:

Scientists used a mathematical model to understand human impact and threats to the Atlantic coast of the United States.
Key Terms
+ Coastal
+ Consequence
+ Cumulative risk
+ Ecosystem
+ Ecosystem service
+ Exposure
+ Human impact
+ Marine habitat
+ Ocean,
+ Stressor
+ Sustainable management.

Scientific Methods
+ Case study
+ Computer modeling
+ Risk analysis

Reading Level
+ High school, upper level
+ High school, lower level

AP Environmental Science Topics (from the College Board)
I. Earth Systems and Resources: C. Global Water Resources and Use
II. The Living World: C. Ecosystem Diversity
IV. Land and Water Use: F. Fishing; G. Global Economics
VII. Global Change: C. Loss of Biodiversity

Teacher's Resources
+ Adapted scientific article
+ Student assessment questions with teacher's key
+ Original paper from PLOSOne
+ Opening video
risk_assmt_article.pdf
File Size: 1635 kb
File Type: pdf
Download File
risk_assmt_key.pdf
File Size: 129 kb
File Type: pdf
Download File
risk_assmt_original.pdf
File Size: 6058 kb
File Type: pdf
Download File
Our Incredible Ocean: Now Is the Time to Protect It | National Geographic - YouTube
Our Incredible Ocean: Now Is the Time to Protect It | National Geographic
Duration: 6min
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Summary of Research:

Scientists developed a mathematical model to find out what affects how long herd immunity lasts.
Key terms
+ Cholera
+ Disease
+ Herd immunity
+ Immunity
+ Susceptibility
+ Infectious disease
+ Vaccination

Scientific methods
+ Case study
+ Mathematical modeling

Reading level
+ High School, lower level
+ Middle school

IB Biology Topics and Options (from International Baccalaureate)
Topic 6. Human Physiology: 6.3 Defense against infectious disease
Option B. Biotechnology and Bioinformatics: B.4 Medicine

Teacher's resources
+ Adapted scientific article
+ Student assessment questions with Teacher's key
+ Original scientific paper from PLOS
+ Opening videos

Recommended Resources for Teaching the 'Herd Immunity' Concept
+ Visualization by The Guardian
+ Visualization by The College of Physicians of Philadelphia
+ Worksheet for this online simulator
+ Lesson plan by CDC (2-3 hours for Middle school)
+ Lesson plan by American Association of Immunologists (up to 12 hours for High school)
+ Simulator of real data from thousands of US cities by ​University of Pittsburgh
herd_article.pdf
File Size: 1020 kb
File Type: pdf
Download File
herd_key.pdf
File Size: 111 kb
File Type: pdf
Download File
herd_original.pdf
File Size: 3604 kb
File Type: pdf
Download File
How does herd immunity work? - YouTube
How does herd immunity work?
Duration: 3min
Cholera - YouTube
Cholera
Duration: 2min
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Summary of Research:

Scientists wanted to track malaria hotspots in Bangladesh and their changes through time.
Key terms
+ Malaria
+ Hotspots
+ Disease control

Scientific methods
+ Representative sampling
+ Case study
+ Mapping
+ Surveillance

Reading level
+ High school, upper level
+ High school, lower level

IB Biology Topics and Options (from International Baccalaureate)
Topic 6. Human Physiology: 6.3 Defense against infectious disease
Option B. Biotechnology and Bioinformatics: B.4 Medicine

Teacher's resources
+ Adapted scientific article
+ Student assessment questions with Teacher's key
+ Original scientific paper from Malaria Journal
+ Opening video
bangladesh_article.pdf
File Size: 981 kb
File Type: pdf
Download File
bangladesh_key.pdf
File Size: 79 kb
File Type: pdf
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bangladesh_original.pdf
File Size: 7970 kb
File Type: pdf
Download File
Malaria…on the road to the elimination - Tropical Medicine [By Mahidol] - YouTube
Malaria…on the road to the elimination - Tropical Medicine
Duration: 5.5min
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Summary of Research:

Researchers wanted to know if illegal hunters are the only problem rhinos are facing or other factors also influence their survival.
Key terms
+ Poaching
+ Conservation
+ Rhinos
+ Africa
+ Kruger National Park
+ Climate change

Scientific methods
+ Representative sampling
+ Data extrapolation

Reading level
+ High school, lower level
+ Middle school
+ Elementary school

AP Environmental Science Topics (from College Board)
II. The Living World: A. Ecosystem Structure; C. Ecosystem Diversity
III. Population: A. Population Biology Concepts; B.Human Population
VII. Global Change: C. Loss of Biodiversity

Teacher's resources
+ Adapted scientific article
+ Teacher's key
+ Original scientific paper from PLOS One
+ Opening videos
rhinos2_article.pdf
File Size: 1808 kb
File Type: pdf
Download File
rhinos2_key.pdf
File Size: 109 kb
File Type: pdf
Download File
rhinos2_original.pdf
File Size: 737 kb
File Type: pdf
Download File
SOUTH AFRICA white rhinos, Kruger national park (compilation) - YouTube
South Africa white rhinos, Kruger national park
Duration: 5min
Black Rhino. A Very Close Encounter in the Kruger National Park, South Africa - YouTube
Black Rhino in the Kruger National Park, South Africa
Duration: 5min
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Summary of Research:

Researchers wanted to know how online media influences a pregnant woman's opinion about vaccination against pertussis and the flu.
Key terms
+ Vaccination
+ Vaccination confidence
+ Pregnancy
+ Online media
+ Decision-making

Scientific Methods
+ Mixed methods study
+ Survey research

Reading level
+ High school, lower level
+ Middle school

IB Biology Topics and Options (from International Baccalaureate)
Topic 6. Human Physiology: 6.3 Defense against infectious disease
Option B. Biotechnology and Bioinformatics: B.4 Medicine

Teacher's resources
+ Adapted scientific article
+ Student assessment questions with Teacher's key
+ Original scientific paper from Vaccine journal
+ Opening videos
pertussis_article.pdf
File Size: 1358 kb
File Type: pdf
Download File
pertussis_key.pdf
File Size: 102 kb
File Type: pdf
Download File
pertussis_original.pdf
File Size: 660 kb
File Type: pdf
Download File
Debunking Anti-Vaxxers - YouTube
AsapScience: Debunking Anti-Vaxxers
Duration: 7 min
Vaccine combo is safe in pregnancy, study finds - YouTube
Vaccine combo is safe in pregnancy, study finds
Duration: 1 min
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Summary of Research:

Scientists wanted to use genetic editing to heal β-thalassemia - a genetic disease affecting the body's ability to produce hemoglobin. 

Key Terms
+ Nanoparticle
+ Polymer
+ Genetic disease
+ Genetic sequencing
+ Recessive mutation
+ Genetic cure
+ Blood disorder

Scientific Methods
+ Deep sequencing
+ Fluorescence imaging
+ Genetic engineering
+ Genetic editing
+ Drug delivery

Reading Level
+ High school, upper level
+ High school, lower level

IB Biology Topics and Options (from International Baccalaureate)
Topic 2. Molecular Biology: 2.1 Molecules to metabolism; 2.4 Proteins; 2.5 Enzymes; 2.6 Structure of DNA and RNA
Topic 3. Genetics: 3.1 Genes; 3.4 Inheritance; 3.5 Genetic modification and biotechnology;
Topic 6. Human Physiology: 6.2 The blood system;
Option D. Human Physiology: D.6Transport of respiratory gases

Teacher's Resources
+ Adapted scientific article
+ Student assessment questions with teacher's key
+ Original scientific paper from Nature
+ Opening videos
nanoparticles_article.pdf
File Size: 1293 kb
File Type: pdf
Download File
nanoparticles_key.pdf
File Size: 142 kb
File Type: pdf
Download File
nanoparticles_original.pdf
File Size: 2686 kb
File Type: pdf
Download File
Engineers Made Fake DNA To Fix Genetic Disorders - YouTube
How Scientists Made Fake DNA To Fix Genetic Disorders
Duration: 3.5min
Nanoparticles circulating in an extraembryonic vein (the larger vessel) and an artery (the smaller vessel) 3 hours after the researchers injected them. (To watch, download this mp4 video file, 35 MB. Published by Nature Communications.)
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Summary of Research:

Scientists wanted to develop a way to fix or replace a damaged or missing gene within a person's genome by engineering a protein circuit.
Key Terms
+ Biological circuit
+ Cancer
+ DNA
+ Genes
+ Genetic code
+ Genetic disease
+ Genetically modified organisms (GMO)
+ Molecular biology
+ RNA
+ Synthetic biology
+ Signaling pathway

Scientific Methods
+ Gene editing
+ Gene therapy
+ Genetic modification

Reading Level
+ High school, upper level
+ High school, lower level

IB Biology Topics and Options (from International Baccalaureate)

Topic 2. Molecular Biology: 2.1 Molecules to metabolism; 2.4 Proteins; 2.5 Enzymes; 2.6 Structure of DNA and RNA
Topic 3. Genetics: 3.1 Genes; 3.2 Chromosomes; 3.5 Genetic modification and biotechnology

Teacher's Resources
+ Adapted scientific article
+ Student assessment questions with teacher's key
+ Opening videos


protein_article.pdf
File Size: 1417 kb
File Type: pdf
Download File
protein_key.pdf
File Size: 100 kb
File Type: pdf
Download File
Synthetic Biology Explained - YouTube
Synthetic biology explained
Duration: 6min
Building With Life in an Era of Biology by Design | Joshua Leonard | TEDxYouth@ASFM - YouTube
“Building With Life in an Era of Biology by Design” - TEDxYouth by Dr. Joshua Leonard
Duration: 13min
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Summary of Research:

Researchers wanted to know how people in Haiti perceive malaria and whether they would accept the interventions the government has planned to eliminate this disease.
Key terms
+ Malaria
+ Disease control
+ Mosquito control
+ Social science

Scientific methods
+ Representative sampling
+ Data reconstruction
+ Key informant interview
+ In-depth interview
+ Focus group discussions
+ Content analysis

Reading level
+ High school, lower level
+ Middle school

IB Biology Topics and Options (from International Baccalaureate)
Topic 6. Human Physiology: 6.3 Defense against infectious disease
Option B. Biotechnology and Bioinformatics: B.4 Medicine

Teacher's resources
+ Adapted scientific article
+ Student assessment questions with Teacher's key
+ Original scientific paper from Malaria Journal
+ Opening video
haiti_article.pdf
File Size: 665 kb
File Type: pdf
Download File
haiti_key.pdf
File Size: 93 kb
File Type: pdf
Download File
haiti_original.pdf
File Size: 1196 kb
File Type: pdf
Download File
Malaria Elimination in Haiti - YouTube
Malaria elimination in Haiti.
Duration 3.5min
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