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lactic acidosis is the most common cause of metabolic acidosis in the critical care setting, which has been associated with a large ..read more
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Insulin is known to promote sodium transport and regulate gluconeogenesis in renal proximal tubules. Although protein kinase B (also known ..read more
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In the setting of type-2 diabetes, there are declines of structural stability and functionality of blood capillaries and red blood cells ( ..read more
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Galactose-deficient IgA1 (Gd-IgA1) plays a crucial role in the development of IgA nephropathy (IgAN). However, the pathogenic mechanisms ..read more
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Primary hyperoxaluria type 2 is a rare inherited disorder of glyoxylate metabolism causing nephrocalcinosis, renal stone formation and ..read more
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Renal cell carcinoma (RCC) has poor survival prognosis because it is asymptomatic at an early, more curative stage. Recently, urine ..read more
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Regardless of the etiology, acute kidney injury involves aspects of mitochondrial dysfunction and ATP depletion. Fatty acid oxidation is ..read more
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Renal allograft rejection can be prevented by immunological tolerance, which may be associated with de novo formed lymphatic vessels in the ..read more
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Clinical risk factors explain only a fraction of the variability of estimated glomerular filtration rate (eGFR) decline in people with type ..read more
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Iron deficiency, anemia, hyperphosphatemia, and increased fibroblast growth factor 23 (FGF23) are common and interrelated complications of ..read more

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