Life Chemicals Blog » Computational Chemistry
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Life Chemicals is a well-known producer and supplier of HTS compounds and a premium provider of custom synthesis and computational chemistry services for pharmaceutical, biotech, agrochemical companies, universities and academic institutions across the globe.
Life Chemicals Blog » Computational Chemistry
1M ago
Driving innovative drug development technologies through targeting helicases, Life Chemicals has designed dedicated Screening Sets of potential helicase inhibitors and related screening compound libraries ..read more
Life Chemicals Blog » Computational Chemistry
2M ago
Our dedicated products, such as the Fluorine Fragment Cocktail Library and the Fluorine Fragment Library, offer valuable resources and advantages for applying fluorine fragment cocktails to various FBDD projects ..read more
Life Chemicals Blog » Computational Chemistry
6M ago
Selective targeted protein degradation emerge as a new approach for the development of more effective and precise drugs. At Life Chemicals, we offer tools and services for crafting new molecular glue degraders like PPI inhibitors, PROTACs, and RIBOTACs ..read more
Life Chemicals Blog » Computational Chemistry
8M ago
Life Chemicals offers small drug-like screening libraries with potential activity against various targets involved in signal cascades aimed for various drug discovery projects: apoptosis signaling, PI3K/Akt/mTOR, RAS/MAPK ..read more
Life Chemicals Blog » Computational Chemistry
1y ago
Nuclear receptors are a class of proteins that play an essential role in the regulation of gene expression. Nuclear receptor-based drugs hold great potential for the treatment of various diseases. In this connection, Life Chemicals offers a collection of dedicated Screening Libraries ..read more
Life Chemicals Blog » Computational Chemistry
1y ago
Research efforts that seek to prioritize the selection of screening compound libraries or sub-libraries for experimental evaluation can take advantage of chemical diversity to increase the probability of finding new scaffolds ..read more
Life Chemicals Blog » Computational Chemistry
1y ago
Rapidly developing structure-based drug design (SBDD) is mainly based on various computational techniques, which allow for the automation and acceleration of the drug design workflow. Life Chemicals offers its proprietary collection of 3D-shaped and Fsp3-enriched screening compounds for efficient drug discovery ..read more
Life Chemicals Blog » Computational Chemistry
1y ago
Transcription factors are involved in various diseases, including cancer, diabetes, neurological, autoimmune, inflammatory disorders, cardiovascular disease, and parasitic infections. To promote the transcription-related drug discovery, Life Chemicals presents distinctive collections of drug-like screening compounds competent for TF modulation research ..read more
Life Chemicals Blog » Computational Chemistry
1y ago
Given the complementary benefits and capabilities of the two screening methods, Life Chemicals considers both approaches for creating the most diverse and balanced collection of screening compound libraries for HTS efforts in drug discovery ..read more
Life Chemicals Blog » Computational Chemistry
1y ago
Compound solubility is a crucial factor in medicinal chemistry and drug discovery, as it greatly influences the ADMET profile of potential drug candidates. Computational, methods are an important tool for predicting and calculating compound solubility in silico ..read more