Promising drug combination for multiple myeloma treatment
ScienceDaily » Multiple Myeloma
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3w ago
New research has found that venetoclax, a medication currently approved for leukemia, has benefits for patients with multiple myeloma when used in combination with another drug. This discovery offers a new avenue of treatment options for the currently incurable disease ..read more
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Obesity linked to detection of blood cancer precursor
ScienceDaily » Multiple Myeloma
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3M ago
Individuals with obesity are more likely to have monoclonal gammopathy of undetermined significance (MGUS), a benign blood condition that often precedes multiple myeloma, according to new research ..read more
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Diabetes may accelerate blood cancer growth, yet survival outcomes differ by race
ScienceDaily » Multiple Myeloma
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7M ago
Patients with multiple myeloma, a blood cancer of plasma cells in the bone marrow, who also have diabetes have a reduced overall survival when compared to those without diabetes. In a subgroup analysis, this difference in survival due to diabetes was seen in White patients but not in Black patients, according to a new study ..read more
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A dendritic cell vaccine was safe and induced immune responses in patients with multiple myeloma
ScienceDaily » Multiple Myeloma
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7M ago
A dendritic cell vaccine administered before and after autologous stem cell transplant (ASCT) was safe and immunogenic and was associated with durable clinical responses in patients with high-risk multiple myeloma ..read more
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New insights to enhance treatment and diagnosis of blood cancer
ScienceDaily » Multiple Myeloma
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7M ago
A ground-breaking study has revealed crucial insights into the role of the histone methyltransferase NSD2 and its epigenetic target PKC-alpha in causing t(4;14) translocated multiple myeloma (MM), a high-risk subtype of blood cancer, to be more aggressive and resistant to treatment ..read more
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Targeting cancer with a multidrug nanoparticle
ScienceDaily » Multiple Myeloma
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1y ago
Chemists designed a bottlebrush-shaped nanoparticle that can be loaded with multiple drugs, in ratios that can be easily controlled. Using these particles, the researchers calculated and delivered the optimal ratio of three cancer drugs used to treat multiple myeloma ..read more
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COVID-19 vaccination protects people with blood cancer
ScienceDaily » Multiple Myeloma
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1y ago
Researchers have demonstrated that people suffering from blood cancer have a good immune response to COVID-19 vaccinations. Vaccination protects patients with B-cell lymphoma and multiple myeloma against severe illness from COVID-19. Some patients even form highly potent antibodies ..read more
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Enzyme inhibition promotes bone formation and curbs the development of bone metastases
ScienceDaily » Multiple Myeloma
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1y ago
In our bones, specialized cells called osteoblasts are responsible for building up bone substance. A team of researchers has now identified an enzyme that controls the activity of osteoblasts. An agent that inhibits the activity of this enzyme reduced cancer-related bone loss and the number of bone metastases in multiple myeloma and in lung and breast cancer models in mice ..read more
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Experimental cancer therapy shows success in more than 70% of patients in global clinical trials
ScienceDaily » Multiple Myeloma
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1y ago
A new therapy that makes the immune system kill bone marrow cancer cells was successful in as many as 73 percent of patients in two clinical trials ..read more
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Researchers find treatment options for patients whose blood cancer relapses after CAR-T
ScienceDaily » Multiple Myeloma
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1y ago
Researchers have identified therapies that can help patients with the blood cancer multiple myeloma who try an immunotherapy known as CAR-T only to find their cancer coming back afterwards ..read more
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