We finally learn from TACT2 what we should have known two decades ago: Chelation therapy doesn’t work for heart disease
Science-Based Medicine » Clinical Trials
by David Gorski
1w ago
At SBM, we've long argued that chelation therapy for heart disease is quackery. An abstract presented recently finally confirmed that. Why did it take so long? The post We finally learn from TACT2 what we should have known two decades ago: Chelation therapy doesn’t work for heart disease first appeared on Science-Based Medicine ..read more
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COVID-19 vaccine-caused “turbo cancer” nonsense just keeps getting more turbocharged
Science-Based Medicine » Clinical Trials
by David Gorski
2w ago
No matter how implausible it is or how weak the evidence for it is, the myth that COVID vaccines cause "turbo cancer" just won't die. Quite the contrary, alas. Antivaxxers are—dare I say?—turbocharging it with bad science. The post COVID-19 vaccine-caused “turbo cancer” nonsense just keeps getting more turbocharged first appeared on Science-Based Medicine ..read more
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Fenbendazole is fast becoming the laetrile of the 2020s
Science-Based Medicine » Clinical Trials
by David Gorski
2M ago
Antivaxxers who "repurposed" deworming drugs like ivermectin and fenbendazole are peddling cancer "miracle cure" testimonials that remind me of laetrile and Stanislaw Burzynski. Truly, everything old is new again. The post Fenbendazole is fast becoming the laetrile of the 2020s first appeared on Science-Based Medicine ..read more
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Adios Aduhelm
Science-Based Medicine » Clinical Trials
by Scott Gavura
3M ago
The controversial and never-proven-effective drug to treat Alzheimer's disease, aducanumab (Aduhelm) has been discontinued. The post Adios Aduhelm first appeared on Science-Based Medicine ..read more
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Pegcetacoplan (Syfovre™) for macular degeneration: an update
Science-Based Medicine » Clinical Trials
by David Weinberg
4M ago
SBM's guest contributor and ophthalmologist, Dr. David Weinberg, provides an update on the phase 3 trials of pegcetacoplan for macular degeneration. The results are still disappointing. The post Pegcetacoplan (Syfovre™) for macular degeneration: an update first appeared on Science-Based Medicine ..read more
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2023: The year that the evidence-based medicine (EBM) paradigm was weaponized against vaccines and public health
Science-Based Medicine » Clinical Trials
by David Gorski
4M ago
Evidence-based medicine (EBM) has been a very useful paradigm for assessing evidence in medicine. However, like any other framework, it can be misused, particularly when fundamentalist EBM methodolatry leads to its inappropriate application to questions for which it is ill-suited, a misuse that has been weaponized against public health during the pandemic. The post 2023: The year that the evidence-based medicine (EBM) paradigm was weaponized against vaccines and public health first appeared on Science-Based Medicine ..read more
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Make Acupuncture Great Again
Science-Based Medicine » Clinical Trials
by Mark Crislip
5M ago
Calling a losing study a win. Making acupuncture great again. The post Make Acupuncture Great Again first appeared on Science-Based Medicine ..read more
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Yet Another Alzheimer’s Drug
Science-Based Medicine » Clinical Trials
by Steven Novella
10M ago
A third drug either FDA approved or showing clinical benefit for Alzheimer's disease confirms that the world of AD treatment has changed forever. The post Yet Another Alzheimer’s Drug first appeared on Science-Based Medicine ..read more
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The effects of vitamin D supplementation on major cardiac events
Science-Based Medicine » Clinical Trials
by Scott Gavura
11M ago
A large randomized controlled trial of vitamin D supplementation generates good data to show there is likely no benefit. The post The effects of vitamin D supplementation on major cardiac events first appeared on Science-Based Medicine ..read more
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RFK Jr. resurrects an old antivax half-truth about “saline placebos” in randomized controlled trials of vaccines
Science-Based Medicine » Clinical Trials
by David Gorski
11M ago
Robert F. Kennedy, Jr. has resurrected the antivax claim that the childhood vaccine schedule has never been tested in randomized controlled trials (RCTs) with a saline placebo controls (and therefore the vaccine schedule is unsafe). This is an old and deceptive antivax half-truth that ignores both what constitutes a scientifically valid placebo and the ethical requirements for RCTs. The post RFK Jr. resurrects an old antivax half-truth about “saline placebos” in randomized controlled trials of vaccines first appeared on Science-Based Medicine ..read more
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