In episode 573, James and Mike invite Jamie Falk back to the podcast to help us simplify all the evidence around using antipsychotics for difficult to treat depression. They do seem to “work”, but you really need to know the numbers around what “work” means. At the end of the podcast, you will! Show notes 1) Tools for Practice Overcoming Resistance: Antipsychotics for difficult to treat depression 2) MAKING EVIDENCE MATTER for EVERYONE CONFERENCE Vancouver May 24/25, 2024 ..read more

In episode 572, James and Mike invite Samantha Moe back to the podcast to go over the evidence around the safety and effectiveness of the monoclonal antibodies used to reduce the risk of respiratory syncytial virus (RSV) infections in infants. We go over all the numbers for hospitalizations and death so you can make evidence-informed decisions. Show Notes 1) Tools for Practice Preventing RSV Infections in Infants 2) MAKING EVIDENCE MATTER for EVERYONE CONFERENCE Vancouver May 24/25, 2024 https://hectalks.com ..read more

In episode 569, James and Mike continue to go over what statistics really show – we focus on what inferential statistics can and cannot do, what a p value means and more importantly what it doesn’t mean. And yes we try to keep all this stat stuff on a realistic and practical level – easier said than done. Show Notes Sensible Medicine Doing statistics can be difficult but understanding them can be fairly simple ..read more

In episode 568, James and Mike go over what statistics really show – and importantly what they don’t show. We go over the terms and nuances and hopefully put them all into a simple context. Statistics are not just in medicine – they are in much of what you do every day – so you really do need to understand them. Show Notes Sensible Medicine Doing statistics can be difficult but understanding them can be fairly simple ..read more

In episode 567, Mike and James revisit the old topic of industry influence on health care providers. We go over the issues, the nuances and some of the latest evidence around the interactions, the influence, and patient perceptions. Show Notes 1) Industry Evidence Handout 2) MAKING EVIDENCE MATTER for EVERYONE CONFERENCE Vancouver May 24/25, 2024 Home ..read more

In episode 566, Mike and James invite Émélie back yet again to the podcast and the topic is the balance of benefits to harms of using corticosteroids in adults or children for atopic dermatitis. We come to the realization, as always, that how to use topical corticosteroids is based on knowing the best available evidence and then using lots of common sense – we give you all of that in just 30 minutes. Show notes Tools for Practice Topical corticosteroids for atopic dermatitis – More than skin deep MAKING EVIDENCE MATTER for EVERYONE CONFERENCE Vancouver May 24/25, 2024 ..read more

In episode 565, Mike and James invite Émélie Braschi back to the podcast to talk about do-it-yourself hearing aids. We find some very interesting information about how direct-to-consumer self-fitted hearing aids compare to conventional hearing aids fitted via audiogram. You really need to listen to this podcast – your patients will thank you. Show notes Tools For practice Do-It-Yourself Hearing Aids MAKING EVIDENCE MATTER for EVERYONE CONFERENCE Vancouver May 24/25, 2024 ..read more

Episode 564: Can non-hormonal drugs improve vasomotor symptoms in menopause? In episode 564, Mike and James invite Samantha Moe back to the podcast to talk about the benefits and harms of non-hormonal medications for vasomotor symptoms in menopause. We find they do have an effect over placebo but also people in the placebo group improve, so you need to know all the numbers. We give you those and so much more so please spend 28 minutes with us when you get a chance. Show notes Tools For Practice Turn Down the Heat! Can non-hormonal drugs improve vasomotor symptoms in menopause? MAKING EVIDENCE ..read more

In episode 563, Mike and James go over all the RCT evidence for the Respiratory Syncytial Virus (RSV) vaccine in older adults. You need to know the vaccine works, but you really need to know the baseline risk of RSV before anyone can really make an informed decision about this vaccine. We’ll do our best to give you all the numbers. Show notes Preventing RSV in the elderly MAKING EVIDENCE MATTER for EVERYONE CONFERENCE Vancouver May 24/25, 2024 ..read more

In episode 560, Mike and James finish their discussion around the use of hallucinogens/psychedelics by going over the psilocybin evidence. As with ketamine we cover the many limitations of the evidence around psilocybin and also talk about the side effects, costs and inconvenience. So now you know all we know for what that is worth. Show notes HANDOUT From Hallucinations to Healing: The Rise of Novel Mental Health Therapies ..read more