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NEJM Journal Watch » Oncology And Hematology

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NEJM Journal Watch features summaries of and commentary on oncology and hematology medical journal articles covering topics such as breast cancer, gastrointestinal cancer, malignant hematology, benign hematology, etc. Follow to get updates.

Sentinel Node Biopsy Without Axillary Dissection in Patients with Sentinel-Node Metastases

NEJM Journal Watch » Oncology And Hematology

by William J. Gradishar, MD

1d ago

Survival was similar with and without completion axillary lymph node dissection in patients with clinically node-negative breast cancer and sentinel node metastases ..read more

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Does Adding Pembrolizumab to Chemoradiotherapy Improve Survival in Patients with Locally Advanced Cervical Cancer?

NEJM Journal Watch » Oncology And Hematology

by Merry Jennifer Markham, MD, FACP, FASCO

1w ago

The addition of pembrolizumab to standard chemoradiotherapy followed by pembrolizumab maintenance improved progression-free survival compared with chemoradiotherapy alone ..read more

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Adding an Immune Checkpoint Inhibitor to BRAF/MEK Inhibitors for BRAF V600E-Mutated Anaplastic Thyroid Cancer

NEJM Journal Watch » Oncology And Hematology

by Hyunseok Kang, MD, MPH, FACP

1w ago

Adding pembrolizumab to combined dabrafenib and trametinib shows a promising improvement in patients' overall survival in a retrospective, single-center study ..read more

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A New Adjuvant Regimen for Patients with Early Breast Cancer: Interim Results

NEJM Journal Watch » Oncology And Hematology

by William J. Gradishar, MD

1w ago

Adding ribociclib to endocrine therapy improved invasive disease–free survival in a diverse group of patients with estrogen-receptor positive, HER2− cancer ..read more

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Diagnosing Heparin-Induced Thrombocytopenia: How Accurate Is the Recommended Algorithm?

NEJM Journal Watch » Oncology And Hematology

by Daniel D. Dressler, MD, MSc, MHM, FACP

1w ago

Sensitivity and specificity were high, but a small proportion of patients assessed as low risk might deserve further testing ..read more

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A Model for Managing Patients with Monoclonal Gammopathy of Undetermined Significance

NEJM Journal Watch » Oncology And Hematology

by Allan S. Brett, MD

1w ago

A new prediction model indicates which patients with MGUS should be considered for bone marrow sampling ..read more

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High-Dose Chemotherapy for Primary Central Nervous System Lymphoma

NEJM Journal Watch » Oncology And Hematology

by Michael E. Williams, MD, ScM

2w ago

Almost 60% of patients older than 65 achieved a 12-month progression-free survival after intensive induction therapy and consolidative autologous stem-cell transplantation ..read more

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T-Cell Immunotherapy for Posttransplant EBV-Positive Lymphoma

NEJM Journal Watch » Oncology And Hematology

by Michael E. Williams, MD, ScM

2w ago

Half of patients with relapsed/refractory EBV-positive posttransplant lymphoproliferative disorder responded to tabelecleucel, an allogeneic T-cell immunotherapeutic agent ..read more

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Antifungal Therapy for Patients with Leukemia — Are We Ready for Stewardship?

NEJM Journal Watch » Oncology And Hematology

by Anna Wald, MD, MPH

3w ago

Many patients with hematologic malignancies receive antifungal therapy despite absence of proven invasive fungal infections ..read more

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Distal DVTs Are High Risk in Patients with Cancer

NEJM Journal Watch » Oncology And Hematology

by Daniel D. Dressler, MD, MSc, MHM, FACP

3w ago

Distal and proximal deep venous thrombosis were associated with similar outcomes in patients with cancer ..read more

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