Happy International Women’s Day 2023 from Future Science Group! To celebrate we have collated our 'Advice to my younger self' interviews from our digital hubs into a helpful infographic. Download now to view the advice from our female leaders, as well as their top resources to help broaden your networks and meet more like-minded women in science. All of our International Women’s Day content from across our digital hubs can be found here. View the infographic The post International Women’s Day with Future Science Group: Advice from our female leaders in STEM appeared first on RegMedNet ..read more

At Advanced Therapies Week 2023 (17–20 January 2023; Miami Beach Convention Center; FL, USA), we caught up with Kathie Schneider (Director, Global Commercial Lead with Terumo Blood and Cell Technologies; Terumo BCT; CO, USA) to discuss the challenges associated with cell and gene therapies and considerations to make when creating guidelines for this field. Terumo Blood and Cell Technologies is a medical company that focuses on taking the power of blood and cells and optimizing them to unlock their potential to help enable different therapies. What were some of the key takeaways from the panel ..read more

To celebrate International Women’s Day (8 March) and acknowledge the often challenging career path taken by women in science we spoke to Tanya Sharma, co-founder of Assurea LLC (NC, USA) about  her inspirations as a woman in science, the resources and mentors she draws upon to support her career development andd how learning from her mentors helped Assurea find and fill an unmet need in the market. Tanya Sharma Co-founder of Assurea LLC (NC, USA) Assurea is a boutique quality compliance consulting firm that serves as a quality and computer system validation delivery partner for fast-gro ..read more

Dr. Elfie Rödel is a Project Manager in the Development Department of PromoCell (Heidelberg, Germany) where she has worked for almost 10 years, exploring the development and optimization of cell culture products and special product applications, such as 3D culturing. With a primary focus on epithelial cells Elfie is working to reduce the use of animal-derived components or serum factors in culture medium and improving the utility and practicality of implementing organoids and complex cell models in research pipelines Here, Elfie discusses selecting appropriate 3D cultures for different applic ..read more

Researchers have combined a hydrogel material with transplanted neural stem cells to grow brain tissue. Brain tissue does not have the same regenerative capacity as other tissues in our body, for example skin, especially when there is a loss of brain parenchyma (the functional tissue in the brain). Developing ways to promote neuronal tissue growth is desired to treat parenchymal defects following traumatic brain injuries and diseases including cancer. A team of researchers at Hokkaido University (Sapporo, Japan) have engineered a hydrogel that provides an effective scaffold for neur ..read more

The use of recombinant adeno-associated viral (rAAV) vectors has fueled unprecedented growth in the cell and gene therapy space. But while promising, rAAV-based therapies are analytically challenging. What’s more, traditional analytical methods are poorly suited to both rAAV characterization and the fast pace of the cell and gene therapy sector. Here, we discuss the analytical challenges of rAAV manufacturing, the pitfalls of traditional analytical approaches, and how orthogonal, direct biophysical characterization methods can help overcome these challenges. rAAVs: an analytical headache Ensu ..read more

Researchers have identified a potential mechanism of action of mesenchymal stem cell therapy for multiple sclerosis.   Mesenchymal stem cell (MSC) therapy has emerged as a promising area of research for multiple sclerosis (MS). In findings published in Regenerative Medicine, a team of researchers from Tisch MS Research Center of New York (USA) has identified a potential therapeutic target for a cell therapy utilizing mesenchymal stem cell-derived neural progenitor (MSC-NP) cells.   MS is characterized by the progressive loss of myelin sheath around the nerve fibers. Whilst the ..read more

This week: Vertex licenses ImmunoGen’s antibody-drug conjugate technology for gene editing research, positive data from Krabbe disease gene therapy trial presented at WORLDSymposium and Thymmune lands US$7 million to develop thymus cell therapy platform. The news highlights: Vertex licenses ImmunoGen’s antibody-drug conjugate technology for gene editing research Positive data from Krabbe disease gene therapy trial presented at WORLDSymposium Thymmune lands US$7 million to develop thymus cell therapy platform Vertex licenses ImmunoGen’s antibody-drug conjugate technology for gene editing res ..read more

At Advanced Therapies Week 2023 (17–20 January 2023; Miami Beach Convention Center; FL, USA), we talked to Bruce Levine about how we can improve patient access to CAR-T therapies.  Bruce is a professor of cancer gene therapy at the University of Pennsylvania (PA, USA) and the Founding Director of their clinical cell and vaccine production facility. He is the co-founder of two spinout companies from the university, Tmunity Therapeutics (PA, USA) and Capstan Therapeutics (CA, USA), as well as the immediate past President of the International Society for Cell and Gene Therapy. What has ..read more

In this ‘Peek behind the paper’, we speak to Violaine Harris from the Tisch Multiple Sclerosis Research Center of New York (USA) about her recent research article published in Regenerative Medicine. Dr Harris gives us a summary of her research and shares her insight into the challenges of understanding the mechanism of action of mesenchymal stem cell-neural progenitors and how the results of this study could benefit research into other neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS) and Alzheimer’s disease. Violaine Harris is a senior research scientist at the Tis ..read more