European Urology
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European Urology, The Platinum Journal, published continuously since 1975, is an international peer-reviewed journal devoted to urology and related sciences and is published monthly. European Urology is the official journal of the European Association of Urology (EAU), a scientific society with more than 15,000 members from 120 countries worldwide.
European Urology
14h ago
The International Society of Urological Pathology and Genitourinary Pathology Society differ in their recommendations for reporting of minor components of high-grade pattern in prostatectomy specimens. This can affect the grade group assigned, particularly when there are only two Gleason patterns in a cancer nodule. We therefore argue that the term “tertiary” should be changed to “minor” component ..read more
European Urology
14h ago
Logothetis and Hahn [1] start their insightful commentary with the observation that, despite many recent advances in prostate cancer (PCa) treatment, there has been limited improvement in overall survival (OS) in androgen-deprived men with PCa. They then proffer the view that this is because of an “overlap syndrome”, whereby age-related medical conditions are exacerbated by androgen signal inhibition (ASI) used to control PCa ..read more
European Urology
14h ago
We appreciate the insights that Dr. Wassersug and his team highlight in their letter on our paper [1], which aims to shed light on the concept of an “overlap syndrome” and emphasize the importance of estradiol (E2) in the context of this syndrome. We agree with the authors that it is important to address comorbid conditions to improve outcomes for men with advanced prostate cancer. However, the overlap syndrome warrants further explanation. The objective in defining the overlap syndrome is to identify a common biologic vulnerability between prostate cancer and its associated illnesses, rather ..read more
More Than Words: Defining Adjuvant, Consolidative, and Salvage Treatment after Radical Prostatectomy
European Urology
14h ago
After radical prostatectomy, adjuvant therapy should be used sparingly when prostate-specific antigen (PSA) is undetectable. Instead, early salvage therapy is recommended for PSA recurrence. Patients with PSA persistence after prostatectomy are at high risk and should be offered consolidative therapy ..read more
European Urology
2d ago
The PReclude infection EVEnts with No prophylaxis (PREVENT) trial was a multicenter US-based randomized controlled superiority study comparing infectious complications of transperineal biopsy (TP) without antibiotic prophylaxis to transrectal biopsy (TR) with targeted antibiotic prophylaxis based on rectal culture. Cancer detection and other complications including pain were also assessed. The trial focused on biopsy naïve-patients, mainly with suspicious multiparametric magnetic resonance imaging results (approximately 90% of men had a PIRADS score 3–5) [1 ..read more