Colorado Cancer Blogs
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Colorado Cancer Blogs
4y ago
When prostate cancer spreads, it most often spreads to bone. And while the 5-year survival rate for prostate cancer that has not spread is nearly 100 percent, once the disease reaches bone, the 5-year survival rate is only 29 percent. Now a University of Colorado Cancer Center study published in the Journal for Immunotherapy of Cancer suggests a new approach, or, possibly two new approaches against these bone metastases: While targeted therapies and anti-cancer immunotherapies have not been especially successful against primary prostate cancers, the study suggests that both these approaches ma ..read more
Colorado Cancer Blogs
4y ago
Since the 1940’s, blocking the body’s production of androgen
has been the only systemic therapy against prostate cancer. Today, while we’ve
gotten better at targeting androgen signaling, treatments targeting the genetic
causes of prostate cancer have lagged behind those for other forms of the
disease.
Until now.
A University of Colorado Cancer Center study published in the
journal Molecular Cancer Research shows that one of the essential
genetic features of an aggressive form of prostate cancer may also be its
Achille’s heel. Prostate cancers that lose the gene MAP3K7 are genetic ..read more
Colorado Cancer Blogs
4y ago
The Costello lab, James Costello, PhD, at left
The National Cancer Institute (NCI) is set up to fund individual
projects in fields like genomics, computational biology, and pathology. Now
researchers at University of Colorado Cancer Center are taking advantage of an
innovative new program in cancer systems biology to combine the three research
areas, earning a prestigious “U01” grant to study the complex genetic drivers
of aggressive prostate cancer. By combining the tools of pathology,
computational modeling and genomics, the project hopes to discover and test
therapeutic interventions for ..read more
Colorado Cancer Blogs
5y ago
For most people finding out that they have prostate cancer multiple times in the span of just a few years seem like a cruel joke. But Jonathan Ormes is not most people. After being told for the third time that he had the disease he decided to take a chance on a University of Colorado Cancer Center study drug that, so far, is controlling his cancer. Ormes is not letting prostate cancer slow him down. In fact, he is using his experience to create poetry.
Ormes before initial diagnosis
An unrelenting disease
Ormes was diagnosed with prostate cancer in 2009 during a digital rectal exam (D ..read more