Organic Chemistry Frontiers Blog
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Organic Chemistry Frontiers publishes high quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies.
Organic Chemistry Frontiers Blog
2w ago
Kinetic vs. thermodynamic control of β-functionalized cyclic ketones: a theoretical investigation of regioselective formation of enolatesManuel Petroselli* and Corrado BacchiocchiOrg. Chem. Front., 2022, 9, 6205-6212https://doi.org/10.1039/D2QO01343F
Thermodynamic- and kinetic-controlled deprotonation of symmetric and asymmetric ketones is a well-known process that leads to the formation of enolates, one of the most important intermediate in organic chemistry. Regio-selective deprotonation assumes extreme importance, being critical to the success of organic reactions, when unsym ..read more
Organic Chemistry Frontiers Blog
2M ago
We are proud to announce the three best covers of Organic Chemistry Frontiers in 2023! The awarded works were chosen by our readers through a worldwide vote. To learn more about the science behind the winning pieces, read the cover articles below for free until 29 February 2024.
Ligand-assisted olefin-switched divergent oxidative Heck cascade with molecular oxygen enabled by self-assembled imines
Bairong Liu, Jianhang Rao, Weibing Liu, Yang Gao, Yanping Huo, Qian Chen and Xianwei Li *
Org. Chem. Front., 2023, 10, 2128-2137
https://doi.org/10.1039/D3QO00316G
Photo-induced nickel-m ..read more
Organic Chemistry Frontiers Blog
6M ago
We are delighted to announce the establishment of our inaugural Early Career Advisory Board at Organic Chemistry Frontiers. This initiative aims to provide a direct channel for engaging with early-career researchers, supporting their professional development, and infusing our journal with fresh innovative perspectives from the younger generation.
We warmly invite you to nominate an emerging investigator to the board or encourage your colleagues to self-nominate before 30 November 2023.
Role of the Early Career Advisory Board
At Organic Chemistry Frontiers, we value the voices of early-career ..read more
Organic Chemistry Frontiers Blog
8M ago
Emerging Investigator: Chuan He
Position Associate Professor
Postdoc 2013–2017 University of Cambridge
Education 2008–2013 Wuhan University Ph.D.
2004–2008 Wuhan University B.Sc.
Group website http://faculty.sustech.edu.cn/hec/en/
ORCID &nbs ..read more
Organic Chemistry Frontiers Blog
8M ago
Emerging Investigator: Michael C. Young
Position Associate Professor
Postdoc 2014–2016 University of Texas at Austin
Education 2009–2014 University of California, Riverside Ph.D.
2006–2008 Western Carolina University M.Sc.
&nb ..read more
Organic Chemistry Frontiers Blog
8M ago
Oxidative Mizoroki–Heck reaction of unprotected cinnamylamines at ambient temperature under airOlutayo N. Farinde, Vanaparthi Satheesh, Kendra K. Shrestha, Carmen R. Rhinehalt, Vinod G. Landge and Michael C. YoungOrg. Chem. Front., 2023, 10, 3982-3988https://doi.org/10.1039/D3QO00778B
Cinammylamines and 3,3-diarylallylamines represent an important class of molecules for drug discovery, and can serve as intermediates thanks to their olefin functionality which can lead to further elaboration. However, there are numerous challenges in the application of organometallic methods to synthesize h ..read more
Organic Chemistry Frontiers Blog
11M ago
Emerging Investigator: Liang-An Chen
Position Professor
Education 2011–2014 Xiamen University Ph.D.
2008–2011 Xiamen University M.Sc.
2004–2008 Fuyang ..read more
Organic Chemistry Frontiers Blog
1y ago
Emerging Investigator: Guangfan Zheng
Position Associate Professor
Education 2014–2017 Northeast Normal University Ph.D.
2012–2014 Northeast Normal University M.Sc.
2006–2010 Jilin University   ..read more
Organic Chemistry Frontiers Blog
1y ago
Cycloisomerization of 1,n-enynes provides a variety of cyclic compounds via multiple bond cleavage and formation. Since these processes are generally induced by alkyne π-bond activation, transition metal catalysts have been well studied for the selective construction of these cyclic products (Scheme 1A). However, transition metal catalysts can be hardly applied to electron-deficient alkynes having acyl groups or other relative strong electron-withdrawing groups. Since acyl groups can be converted to various functional groups, it is desirable to develop catalyst systems applicable to such start ..read more
Organic Chemistry Frontiers Blog
1y ago
We are proud to announce the three best covers of Organic Chemistry Frontiers in 2022! The awarded work was chosen by our readers through a worldwide vote. To learn more about the science behind the winning pieces, read the cover articles below.
Ni(II)-Catalyzed intermolecular selective Heck-type arylation of unactivated alkenes with arylboronic acids
Cong Lin,* Sai Chen, Yihua Wang, Fei Gao and Liang Shen*
Org. Chem. Front., 2022, 9, 608-614
https://doi.org/10.1039/D1QO01579F
Palladium-catalyzed direct γ-C(sp3)–H arylation of β-alkoxy cyclohexenones: reaction scope and mechanistic ins ..read more