Background: The analgesic effects of Cannabis sativa are mediated by ∆9 tetrahydrocannabinol (THC), but the contributions of other bioactive complex components, including cannabigerol (CBG) and cannabidiol (CBD), are unclear. We describe the individual and combined effects of CBG, CBD and THC, on blocking capsaicin responses in dorsal root ganglion (DRG) neurons, in an in vitro model of nociceptor hypersensitivity. Materials and methods: Adult rat DRG were dissected and enzyme digested to obtain a neuronal suspension in BSF2 medium containing 2% fetal calf serum, and the neurotrophic factors ..read more

<![CDATA[ Aurora Cannabis named its new genetic licensing business, Occo, which is backed by the company’s breeding and genetics facility in Comox, British Columbia, Canada.   Occo will be based out of Aurora’s Coast research and development hub and will be led by Casey Whelan, vice president of genetics business development, who will be responsible for leading Occo’s genetics licensing efforts in Canada and other markets. He joins Aurora after spending a decade in breeding and licensing premium agricultural products, according to a company release. The Occo team includes a number of ..read more

<![CDATA[ BERKELEY, California, December 2, 2021 – PRESS RELEASE – Steep Hill, a commercial cannabis testing lab, has announced its expansion to Illinois.  « We are extremely pleased to partner with Steep Hill Illinois’ passionate and visionary team, » said Nigel Stobart, Steep Hill CEO. « With their success in serial business ventures and commitment to patient and consumer safety with testing, we believe we will see this group expand their horizons quickly. »  Steep Hill is known for its consistency of quality testing, customized technology, and state-of ..read more

Une large légalisation du cannabis médical au Royaume-Uni pourrait rapporter 1,2 milliard de livres et créer 41 437 nouveaux emplois dans le secteur et environ 17 000 emplois auxiliaires, selon un rapport de Volteface, ONG britannique qui cherche à réduire les dommages causés par les drogues aux individus et à la société, par le biais […] L’article Le programme britannique de cannabis médical pourrait rapporter 1,2 milliard de livres sterling est apparu en premier sur Cannabis Belgique ..read more

Am J Gastroenterol. 2021 Dec 1;116(Suppl 1):S3. doi: 10.14309/01.ajg.0000798644.60076.bb. NO ABSTRACT PMID:34848598 | DOI:10.14309/01.ajg.0000798644.60076.bb Source: ncbi 2 Partage le savoir more L’article P011 Prevalence of Cannabis Use Disorder in Inflammatory Bowel Disease Hospitalizations in the United States and Effect on Length of Stay est apparu en premier sur . L’article P011 Prevalence of Cannabis Use Disorder in Inflammatory Bowel Disease Hospitalizations in the United States and Effect on Length of Stay est apparu en premier sur Cannabis Belgique ..read more

<![CDATA[ PORTLAND, Ore., Nov. 18, 2021 – PRESS RELEASE – Thompson Duke Industrial, a leader in cannabis oil vaporizer device filling and capping equipment, has been granted another patent from the United States Patent and Trademark Office (USPTO). U.S. Patent No. 11,166,490 covers Thompson Duke’s proprietary cannabis oil vaporizer device filling system, particularly adapted for filling sealed vaporizer devices. « We are honored that the USPTO has once again recognized the novelty and authenticity of our technology here at Thompson Duke, » said Chris Gardella, chief ..read more

<![CDATA[ California is working to develop statewide standardized cannabis testing to minimize inconsistencies in data from one lab to the next.  The move comes after California Gov. Gavin Newsom signed Senate Bill 544 into law Oct. 5. According to the bill text, the measure requires the Department of Cannabis Control (DCC) to “establish one or more standardized cannabinoids test methods to be used by all testing laboratories” on or before Jan. 1, 2023. “I believe it is a necessary step to standardize testing methods and procedures when all legal cannabis products are required to under ..read more

J Natl Cancer Inst Monogr . 2021 Nov 28;2021(58):107-113. doi: 10.1093/jncimonographs/lgab010. Affiliations Expand Affiliations 1 Hematology-Oncology Division, Department of Medicine, University of California, San Francisco, CA, USA. 2 Department of Biochemistry and Molecular Biology, School of Biology, Complutense University, Madrid, Spain. 3 Group of Cannabinoid Signaling in Cancer Cells, Division of Oncology Research, Instituto de Investigación Sanitaria San Carlos, Madrid, Spain. 4 Department of Oncology, University of Leeds and Leeds Teaching Hospitals Trust, Leeds, England, UK. 5 ..read more

Background and aims: MDMB-4en-PINACA is a synthetic cannabinoid receptor agonist (SCRA) that has recently emerged. Data regarding clinical presentations in the event of intoxication is scarce. This study presents MDMB-4en-PINACA identification in cannabis consumers with clinical and analytical descriptions. Methods: Between November 2020 and March 2021, all patients with unexpected or unusually severe effects and Poisoning Severity Score (PSS) greater than or equal to 2 after cannabis consumption were included. Blood and/or urine samples were collected for toxicological analysis. When availa ..read more

Introduction: Chronic ulcers are the main cause of morbidity and mortality, and the incidence of chronic wounds is expected to increase given that people live longer and that there are civil diseases. Aim: Much attention in the treatment of wounds concerns a dressing that involves wound cleansing, bacterial balance, exudate management and local tissue in a wound environment. These important elements of the evaluation led to the development of an interactive dressing based entirely on flax raw materials. Material and methods: The complete dressing for wound coverage was prepared from plant (f ..read more