Expression of the SARS-CoV-2 receptor-binding domain by live attenuated influenza vaccine virus as a strategy for designing a bivalent vaccine against COVID-19 and influenza
BMC » Virology Journal
by Ekaterina Stepanova, Irina Isakova-Sivak, Daria Mezhenskaya, Sergei Niskanen, Victoria Matyushenko, Ekaterina Bazhenova, Alexandra Rak, Pei Fong Wong, Polina Prokopenko, Tatiana Kotomina, Elena Krutikova, Sergei Legotskiy, Bogdan Neterebskii, Tatiana Ostroukhova, Konstantin Sivak, Yana Orshanskaya…
1w ago
Influenza and SARS-CoV-2 are two major respiratory pathogens that cocirculate in humans and cause serious illness with the potential to exacerbate disease in the event of co-infection. To develop a bivalent va ..read more
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Development of monoclonal antibodies against oropouche virus and its applicability to immunohistochemical diagnosis
BMC » Virology Journal
by Ana Paula Andreolla, Alessandra Abel Borges, Seigo Nagashima, Caroline Busatta Vaz de Paula, Lucia de Noronha, Nilson I.T. Zanchin, Juliano Bordignon and Claudia Nunes Duarte dos Santos
1w ago
Orthobunyavirus oropouche ense virus (OROV), the causative agent of Oropouche fever, is widely dispersed in Brazil and South America, causing sporadic outbreaks. Due to the similarity of initial clinical symptoms ..read more
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A macrophage-cell model of HIV latency reveals the unusual importance of the bromodomain axis
BMC » Virology Journal
by Javan K. Kisaka, Daniel Rauch, Malachi Griffith and George B. Kyei
1w ago
Although macrophages are now recognized as an essential part of the HIV latent reservoir, whether and how viral latency is established and reactivated in these cell types is poorly understood. To understand th ..read more
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Hepatitis B relapse after entecavir or tenofovir alafenamide cessation under anti-viral prophylaxis for cancer chemotherapy
BMC » Virology Journal
by Hsin-Wei Fang, Po-Lin Tseng, Tsung-Hui Hu, Jing-Houng Wang, Chao-Hung Hung, Sheng-Nan Lu and Chien-Hung Chen
1w ago
No study has comparing hepatitis B virus (HBV) relapse rates among patients with both cancer and hepatitis B e antigen (HBeAg)-negative chronic hepatitis B (CHB) who completed anti-viral prophylaxis for chemot ..read more
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Inefficient antiviral response in reconstituted small-airway epithelium from chronic obstructive pulmonary disease patients following human parainfluenza virus type 3 infection
BMC » Virology Journal
by Louise Bondeelle, Maud Salmona, Véronique Houdouin, Elise Diaz, Jacques Dutrieux, Séverine Mercier-Delarue, Samuel Constant, Song Huang, Anne Bergeron and Jérôme LeGoff
2w ago
Chronic obstructive pulmonary disease (COPD) affects over 250 million individuals globally and stands as the third leading cause of mortality. Respiratory viral infections serve as the primary drivers of acute ..read more
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Peg-IFNα combined with hepatitis B vaccination contributes to HBsAg seroconversion and improved immune function
BMC » Virology Journal
by Yisi Liu, Shan Ren, Lina Ma, Xiao Lin, Junfeng Lu, Zhenhuan Cao, Sujun Zheng, Zhongjie Hu, Xiaoxue Xu and Xinyue Chen
2w ago
The purpose of this study was to investigate immunological variations between a group that received the hepatitis B vaccine and a non-vaccine group. We focused on a cohort that achieved HBsAg seroclearance aft ..read more
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DEAD box RNA helicase 5 is a new pro-viral host factor for Sindbis virus infection
BMC » Virology Journal
by Mélanie Messmer, Louison Pierson, Charline Pasquier, Nikola Djordjevic, Johana Chicher, Philippe Hammann, Sébastien Pfeffer and Erika Girardi
2w ago
RNA helicases are emerging as key factors regulating host-virus interactions. The DEAD-box ATP-dependent RNA helicase DDX5, which plays an important role in many aspects of cellular RNA biology, was also found ..read more
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SARS-CoV-2 outbreak: role of viral proteins and genomic diversity in virus infection and COVID-19 progression
BMC » Virology Journal
by Hosni A. M. Hussein, Ali A. Thabet, Ahmed A. Wardany, Ahmed M. El-Adly, Mohamed Ali, Mohamed E. A. Hassan, Mohamed A. B. Abdeldayem, Abdul-Rahman M. A. Mohamed, Ali Sobhy, Mohamed A. El-Mokhtar, Magdy M. Afifi, Samah M. Fathy and Serageldeen Sultan
2w ago
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection is the cause of coronavirus disease 2019 (COVID-19); a severe respiratory distress that has emerged from the city of Wuhan, Hubei prov ..read more
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Efficacy of different doses of corticosteroids in treating severe COVID-19 pneumonia
BMC » Virology Journal
by Ge zhang, Lin Su, Wenwen Wu, Qing Qiao, Shuncui Gao, Yan Zhang and Yanmei Zhang
2w ago
To investigate the efficacy of different doses of corticosteroids in treating severe coronavirus disease 2019 (COVID-19) pneumonia ..read more
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Mendelian randomization analysis reveals causal relationship between obstetric-related diseases and COVID-19
BMC » Virology Journal
by Yan Fang and Dajun Fang
3w ago
Several observational studies demonstrated that pregnant individuals with COVID-19 had a higher risk of preeclampsia and preterm birth. We aimed to determine whether women with COVID-19 diagnosis had adverse p ..read more
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