BMC Bioinformatics
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BMC Bioinformatics is an open access, peer-reviewed journal that considers articles on all aspects of the development, testing and novel application of computational and statistical methods for the modeling and analysis of all kinds of biological data, as well as other areas of computational biology.
BMC Bioinformatics
3d ago
Gene interaction networks are graphs in which nodes represent genes and edges represent functional interactions between them. These interactions can be at multiple levels, for instance, gene regulation, protei ..read more
BMC Bioinformatics
3d ago
Protein kinases are a diverse superfamily of proteins common to organisms across the tree of life that are typically involved in signal transduction, allowing organisms to sense and respond to biotic or abioti ..read more
BMC Bioinformatics
3d ago
Conventional differential gene expression analysis pipelines for non-model organisms require computationally expensive transcriptome assembly. We recently proposed an alternative strategy of directly aligning ..read more
BMC Bioinformatics
3d ago
Background: As noncoding RNAs, circular RNAs (circRNAs) can act as microRNA (miRNA) sponges due to their abundant miRNA binding sites, allowing them to regulate gene expression and influence disease developmen ..read more
Data-driven discovery of chemotactic migration of bacteria via coordinate-invariant machine learning
BMC Bioinformatics
3d ago
E. coli chemotactic motion in the presence of a chemonutrient field can be studied using wet laboratory experiments or macroscale-level partial differential equations (PDEs) (among others). Bridging experimental ..read more
BMC Bioinformatics
1w ago
Stochastic modelling plays a crucial role in comprehending the dynamics of intracellular events in various biochemical systems, including gene-expression models. Cell-to-cell variability arises from the stocha ..read more
BMC Bioinformatics
1w ago
Traditional gene set enrichment analyses are typically limited to a few ontologies and do not account for the interdependence of gene sets or terms, resulting in overcorrected p-values. To address these challenge ..read more
BMC Bioinformatics
1w ago
Relation extraction (RE) plays a crucial role in biomedical research as it is essential for uncovering complex semantic relationships between entities in textual data. Given the significance of RE in biomedica ..read more
BMC Bioinformatics
2w ago
Stroke prediction remains a critical area of research in healthcare, aiming to enhance early intervention and patient care strategies. This study investigates the efficacy of machine learning techniques, parti ..read more
BMC Bioinformatics
2w ago
The dilution-replicate experimental design for qPCR assays is especially efficient. It is based on multiple linear regression of multiple 3-point standard curves that are derived from the experimental samples ..read more