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Journal of Nanobiotechnology

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Journal of Nanobiotechnology is an open access, peer-reviewed, online journal communicating scientific and technological advances in the fields of medicine and biology, with an emphasis in their interface with nanoscale sciences. The journal provides biomedical scientists and the international biotechnology business community with the latest developments in the growing field of Nanobiotechnology.

Macrophage-derived mir-100-5p orchestrates synovial proliferation and inflammation in rheumatoid arthritis through mTOR signaling

Journal of Nanobiotechnology

by Huan Liu, Yuehong Chen, Yupeng Huang, Ling Wei, Jingjing Ran, Qianwei Li, Yunru Tian, Zhongling Luo, Leiyi Yang, Hongjiang Liu, Geng Yin and Qibing Xie

2d ago

Rheumatoid arthritis (RA) is a chronic autoimmune disorder characterized by synovial inflammation, causing substantial disability and reducing life quality. While macrophages are widely appreciated as a master ..read more

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An exosomal strategy for targeting cancer-associated fibroblasts mediated tumors desmoplastic microenvironments

Journal of Nanobiotechnology

by Xiaoxia Xue, Xiangpeng Wang, Mingshi Pang, Liuchunyang Yu, Jinxiu Qian, Xiaoyu Li, Meng Tian, Cheng Lu, Cheng Xiao and Yuanyan Liu

2d ago

Tumors desmoplastic microenvironments are characterized by abundant stromal cells and extracellular matrix (ECM) deposition. Cancer-associated fibroblasts (CAFs), as the most abundant of all stromal cells, pla ..read more

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Exosomal miR-9-5p derived from iPSC-MSCs ameliorates doxorubicin-induced cardiomyopathy by inhibiting cardiomyocyte senescence

Journal of Nanobiotechnology

by Huifeng Zheng, Xiaoting Liang, Baojuan Liu, Xinran Huang, Ying Shen, Fang Lin, Jiaqi Chen, Xiaoyan Gao, Haiwei He, Weifeng Li, Bei Hu, Xin Li and Yuelin Zhang

2d ago

Doxorubicin (DOX) is a chemotherapeutic agent widely used for tumor treatment. Nonetheless its clinical application is heavily limited by its cardiotoxicity. There is accumulated evidence that transplantation ..read more

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Recent advances in enhances peripheral nerve orientation: the synergy of micro or nano patterns with therapeutic tactics

Journal of Nanobiotechnology

by Majid Sharifi, Mohammad Kamalabadi-Farahani, Majid Salehi, Somayeh Ebrahimi-Barough and Morteza Alizadeh

4d ago

Several studies suggest that topographical patterns influence nerve cell fate. Efforts have been made to improve nerve cell functionality through this approach, focusing on therapeutic strategies that enhance ..read more

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Modulation of alveolar macrophage and mitochondrial fitness by medicinal plant-derived nanovesicles to mitigate acute lung injury and viral pneumonia

Journal of Nanobiotechnology

by Lusha Ye, Yanan Gao, Simon Wing Fai Mok, Wucan Liao, Yazhou Wang, Changjiang Chen, Lijun Yang, Junfeng Zhang and Liyun Shi

4d ago

Acute lung injury (ALI) is generally caused by severe respiratory infection and characterized by overexuberant inflammatory responses and inefficient pathogens-containing, the two major processes wherein alveo ..read more

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Tea polyphenol-engineered hybrid cellular nanovesicles for cancer immunotherapy and androgen deprivation therapy

Journal of Nanobiotechnology

by Yiming Guo, Jicheng Wu, Lefan Chen, Lujie Liu, Tianxiang Bi, Yuanwei Pan, Qian-Fang Meng, Chaoliang Wang, Lang Rao and Qi Li

4d ago

Androgen deprivation therapy (ADT) is a crucial and effective strategy for prostate cancer, while systemic administration may cause profound side effects on normal tissues. More importantly, the ADT can easily ..read more

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Systematic review of the osteogenic effect of rare earth nanomaterials and the underlying mechanisms

Journal of Nanobiotechnology

by Ziwei Chen, Xiaohe Zhou, Minhua Mo, Xiaowen Hu, Jia Liu and Liangjiao Chen

1w ago

Rare earth nanomaterials (RE NMs), which are based on rare earth elements, have emerged as remarkable biomaterials for use in bone regeneration. The effects of RE NMs on osteogenesis, such as promoting the ost ..read more

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Mesoporous silica coated spicules for photodynamic therapy of metastatic melanoma

Journal of Nanobiotechnology

by Xuejiao Liang, Jialiang Zhang, Chi Zhang, Haojie Zhai, Ping Yang and Ming Chen

1w ago

We report on the fabrication of mesoporous silicon dioxide coated Haliclona sp. spicules (mSHS) to enhance the delivery of the insoluble photosensitizer protoporphyrin IX (PpIX) into deep skin layers and mediate ..read more

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A pH-responsive nanoplatform with dual-modality imaging for enhanced cancer phototherapy and diagnosis of lung metastasis

Journal of Nanobiotechnology

by Mujie Yuan, Zeyu Han, Yan Li, Xin Zhan, Yong Sun, Bin He, Yan Liang, Kui Luo and Fan Li

1w ago

To address the limitations of traditional photothermal therapy (PTT)/ photodynamic therapy (PDT) and real-time cancer metastasis detection, a pH-responsive nanoplatform (NP) with dual-modality imaging capabili ..read more

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Developing hydrogels for gene therapy and tissue engineering

Journal of Nanobiotechnology

by Chunyu Su, Dini Lin, Xinyu Huang, Jiayin Feng, Anqi Jin, Fangyan Wang, Qizhuang Lv, Lanjie Lei and Wenjie Pan

1w ago

Hydrogels are a class of highly absorbent and easily modified polymer materials suitable for use as slow-release carriers for drugs. Gene therapy is highly specific and can overcome the limitations of traditio ..read more

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