Researchers provide new insights into the brain mechanisms behind psychosis. The research identified malfunctions in two critical brain systems—the "filter" and the "predictor" in individuals with psychosis ..read more

A new study suggests probiotics with vitamin D might improve cognitive function in people with schizophrenia. The study involved 70 adults who took either a placebo or the supplements daily for 12 weeks ..read more

A new study utilizing UK Biobank data has unveiled the genetic roots of left-handedness, pinpointing rare variants in the beta-tubulin gene TUBB4B significantly associated with this trait. These findings not only shed light on the complex interplay between genetics and brain asymmetry but also link left-handedness with neurodevelopmental disorders through shared genetic pathways ..read more

A new pilot study presents a compelling case for the ketogenic diet as a dual-action treatment for individuals with serious mental illnesses like schizophrenia and bipolar disorder, who often suffer metabolic side effects from their medication. The research shows how adopting a ketogenic diet not only mitigates these metabolic issues but also significantly improves psychiatric conditions ..read more

A global study involving 131 researchers from 105 labs across seven countries has found altered brain pH and lactate levels across various animal models of neuropsychiatric and neurodegenerative disorders. This large-scale research reveals a common endophenotype involving energy metabolism dysfunction as a hallmark in disorders such as schizophrenia, autism, and Alzheimer’s ..read more

Researchers provided new insights into brain development, revealing that different brain regions share a similar organizational structure in early stages rather than being pre-specialized. This finding, supported by advanced optical imaging, suggests a universal blueprint for brain development, which has significant implications for understanding neurodevelopmental disorders like autism and schizophrenia ..read more

A new study revealed shared cellular and molecular changes in the brains of people with schizophrenia and older adults, pointing to a common biological basis for cognitive impairments in these groups. The study analyzed gene expression in over a million cells from 191 individuals, uncovering a coordinated reduction in genes supporting synaptic connections by neurons and astrocytes, dubbed the Synaptic Neuron and Astrocyte Program (SNAP ..read more

Researchers developed a groundbreaking blood test capable of measuring the severity and risk of schizophrenia, fundamentally changing the approach to diagnosing and treating this complex psychiatric disorder. The test identifies specific biomarkers that not only predict the condition's progression but also facilitate personalized treatment plans ..read more

Researchers revealed that evaluating parental traits for neurodevelopmental and psychiatric disorders offers a more precise prediction for these conditions in children than genetic testing alone. The study found that children's risk of disorders such as autism and schizophrenia increases when both parents exhibit related traits, including depression and anxiety ..read more

A new study reveals limitations in the current use of mathematical models for personalized medicine, particularly in schizophrenia treatment. Although these models can predict patient outcomes in specific clinical trials, they fail when applied to different trials, challenging the reliability of AI-driven algorithms in diverse settings ..read more