submitted by /u/JuggyLee [visit reddit] [comments ..read more

Question: for amniocentesis, how often do FISH and karyotype/microarray not match? Context: I'm in the excruciating wait during a prenatal diagnosis, after and elevated NT ultrasound, normal NIPT, low mosaic trisomy 18 CVS (4 of 21 cells), and a normal amino FISH result. We are now waiting on microarray and karyotype. Our genetic counselor said this is cautiously good news but that FISH can miss mosaicism. However I'm confused about this since my CVS FISH picked up mosaicism? I guess I'm looking for some different opinions on how often in practice you see an amino FISH that is normal and a ka ..read more

This month, an article was published (in pre-print version, for now) that solves the theoretical problem that was proposed mainly by the article "Mutation bias reflects natural selection in Arabidopsis thaliana", by Monroe and colleagues (2022), in which the authors present solid evidence that more essential genes mutate less frequently. Therefore, the search for a solution to this problem has become important. The mutation bias reported in the article by Monroe and colleagues (2022) is so relevant to evolutionary theory that many (especially advocates of Intelligent Design) have come to beli ..read more

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submitted by /u/vincoug [visit reddit] [comments ..read more

Incoming college freshman here, I plan to do a double major in CS and Biology with a focus on bioinformatics, genomics, and genetics. I am deciding between UW Madison and UIUC, both have good genetics research which I am interested in getting involved in. UW Madison has a genetics major but I thought majoring in genetics would be too much specialization too early, so I am leaning towards UIUC. TL;DR Which has a better undergrad program for a future geneticist UIUC or UW Madison? submitted by /u/H1roWasTaken [visit reddit] [comments ..read more

how do you produce a figure of an alignment DNA sequence for a lab report if it’s already in fastfa form. does it need to be done in excel? submitted by /u/gav_mac [visit reddit] [comments ..read more

I’m TA ing a class and am a little in over my head with the heavy genetics parts… the question asked students to explain how quantitative genetics and population genetics are linked, and how each is important for breeding… And the student included quantitative alleles so just wondering if that works. I’ll ask the prof but what do ya’ll think? submitted by /u/ResistOk9038 [visit reddit] [comments ..read more

/title. submitted by /u/mildlymoony [visit reddit] [comments ..read more

He was discovered in North Africa but which modern human populations would he have the least genetic distance to submitted by /u/Elmointhehood [visit reddit] [comments ..read more