This article is copyrighted by GreenMedInfo LLC, 2024 Visit our Re-post guidelines Breast cancer is a devastating disease that affects millions of women worldwide. While genetic factors have long been considered the primary culprits, a groundbreaking study has revealed that the air we breathe may play a more significant role in the development of this disease than previously thought. read more ..read more

This article is copyrighted by GreenMedInfo LLC, 2024 Visit our Re-post guidelines In a world where depression affects millions, a powerful ally in the fight against this mental health crisis may be found in an unexpected place--the gym. High-intensity interval training (HIIT), a popular workout method, has shown promise in alleviating depressive symptoms, offering hope for those seeking a natural, drug-free approach to managing their mental well-being. read more ..read more

In a world where depression affects millions, a powerful ally in the fight against this mental health crisis may be found in an unexpected place--the gym ..read more

A groundbreaking study has revealed that the air we breathe may play a more significant role in the development of this breast cancer than previously thought ..read more

PMID:  J Med Food. 2024 Feb ;27(2):123-133. Epub 2023 Dec 13. PMID: 38100058 Abstract Title:  Echinacoside Prevents Sepsis-Induced Myocardial Damage via Targeting SOD2. Abstract:  Echinacoside (ECH) is a prominent naturally occurring bioactive compound with effects of alleviating myocardial damage. We aimed to explore the beneficial effects of ECH against sepsis-induced myocardial damage and elucidate the potential mechanism. Echocardiography and Masson staining demonstrated that ECH alleviates cardiac function and fibrosis in the cecal ligation and puncture (CLP) model. Transcr ..read more

PMID:  Mol Nutr Food Res. 2024 Mar ;68(6):e2300553. Epub 2024 Feb 17. PMID: 38366962 Abstract Title:  Echinacoside Exerts Antihepatic Fibrosis Effects in High-Fat Mice Model by Modulating the ACVR2A-Smad Pathway. Abstract:  SCOPE: Nonalcoholic steatohepatitis (NASH) is an increasingly common chronic liver disease in which hepatic fibrosis is the major pathological change. The transforming growth factorβ(TGF-β)/mall mothers against decapentaplegic (Smad) signaling is the main effector of fibrosis. Although the antifibrotic effect of echinacoside (Ech) on the liver has been indica ..read more

PMID:  Biomol Biomed. 2024 Mar 10. Epub 2024 Mar 10. PMID: 38461536 Abstract Title:  Echinacoside ameliorates hepatic fibrosis and tumor invasion in rats with thioacetamide-induced hepatocellular carcinoma. Abstract:  Hepatocellular carcinoma (HCC) affects approximately 800,000 individuals globally each year. Despite advancements in HCC treatments, there is still a pressing need to identify new drugs that can combat resistance. One potential option is echinacoside, a natural caffeic acid glycoside with antioxidant, anti-inflammatory, antidepressant, and antidiabetic properties ..read more

PMID:  Eur J Clin Invest. 2024 Mar 19:e14198. Epub 2024 Mar 19. PMID: 38501711 Abstract Title:  Echinacoside promotes osteogenesis and angiogenesis and inhibits osteoclast formation. Abstract:  PURPOSE: The purpose of this research is to demonstrate echinacoside promotes osteogenesis and angiogenesis and inhibits osteoclast formation.METHODS: We conducted a cell experiment in vitro to study how echinacoside affects angiogenesis, osteogenesis and osteoclast formation. We used polymerase chain reaction and Western blotting to detect the expression levels of proteins and genes ..read more

PMID:  Adv Clin Exp Med. 2024 Mar 20. Epub 2024 Mar 20. PMID: 38506417 Abstract Title:  Anti-inflammatory effect of echinacoside in collagen-induced arthritis via Nrf2/Drp1 pathway. Abstract:  BACKGROUND: Oxidative damage plays an important role in the progression of rheumatoid arthritis (RA). Emerging research evidence suggests that natural antioxidants may effectively ameliorate this disease.OBJECTIVES: To investigate the therapeutic effect of echinacoside (ECH) in a collagen-induced arthritis (CIA) mouse model and thus elucidate the underlying molecular mechanism in RA.MATERI ..read more

PMID:  Phytomedicine. 2024 Jun ;128:155433. Epub 2024 Feb 7. PMID: 38547621 Abstract Title:  Echinacoside ameliorates post-stroke depression by activating BDNF signaling through modulation of Nrf2 acetylation. Abstract:  BACKGROUND: Post-stroke depression (PSD) affects approximately one-third of stroke survivors, leading to adverse outcomes in rehabilitation, reduced quality of life, and increased mortality rates. Despite these implications, the underlying causes of PSD remain unclear, posing challenges for prevention and treatment. Echinacoside (ECH), a natural compound with kn ..read more