In this article, I’m going to explore an independent marker for heart disease that you may not have heard of and is rarely tested in the UK. This marker is Lipoprotein(a). I will discuss what it is, what different levels are and how to manage it if you have raised levels. Cardiovascular disease (CVD) is the leading cause of death and a reduced healthspan. Managing and reducing the risk of CVD is, therefore, essential to a long and healthy life. The healthy guy who drops dead from a heart attack We’ve all heard of that healthy person, who suffers a fatal heart attack out of the blue. It turns ..read more

Testosterone - the hormone that makes effort enjoyable. The impact of testosterone on mood, motivation and mental health is often overlooked. Yet testosterone and dopamine levels in the brain are deeply connected. In this video I explain a bit more about this and the science that backs it up.     In men, testosterone levels reduce by around 1% per year from the age of 30. That has a big impact on, yes, muscle and strength, but it also affects cholesterol profiles, the perception of energy, mitochondrial health, mental health and motivation. There is increasing evidence that testoste ..read more

Manopause fact or fiction? The andropause, commonly referred to as 'manopause': is it a real phenomenon or are men just getting on the bandwagon of hormone replacement? It is certainly true that hormone levels in men, in particular testosterone, do decrease with.  Men experience a gradual decline in testosterone levels by about 1% per year, starting around age 30. This means the drop by around 20% by the age of 50. However, this is a slow, insidious decrease rather than the sudden change that happens to women in the menopause. That is not to say it is unimportant. In fact, this slow ..read more

Did you know that prolactin, a hormone that is usually associated with lactation in women, plays a surprisingly important role in men's health, influencing everything from sexual function to mood, motivation, and energy levels? A lot of this due to its interplay with testosterone and dopamine. It should be checked when performing a testosterone test in men, as high levels of prolactin are associated with and can cause low testosterone. A raised prolactin is usually caused by lifestyle or medication. Understanding why levels might be low is the first step when optimising testosterone level ..read more

Introduction Why size really matters when it comes to cholesterol Dementia and heart disease are not only leading causes of death in the UK but also major contributors to reduced quality of life. A common factor between them? Cholesterol levels. While there's a push for widespread use of cholesterol-lowering medication, it's vital to understand that not all cholesterol is equal. In this blog, I explain: Advanced lipid testing, focusing on key players like Apolipoprotein B (ApoB) and lipoprotein(a) to help you understand what they mean and why they matter. What an apolipoprotein is H ..read more

  Dr Geoff Mullan was interviewed along with Dr Melaney Angelova and Dr Anne Moore for the Daily Telegraph for their take on how to supplement your diet and stay healthy this Winter. "From omega-3 to the new anti-ager causing a buzz, expert advice on which ones are really worth spending your money on." If you have an account with the Daily Telegraph, you can read the full article using the link below (requires a paid subscription). For those of you that don't, we have taken some of the main points from the article. Link to full article Don't have a subscription, we have made a summa ..read more

Summary Do a Vitamin D home test, they are cheap and easy to do. Start with 2000 IU or 4000IU depending on your levels. K2: Get a D3 that is already combined with 100 mcg K2, it stops artery calcification and strengthens your bones. Magnesium: Add magnesium threonate in the morning 500-1000mg or Magnesium glycinate at night 2-400mg B12: Good to add: Methyl or hydroxy cobalamin 1000mcg Check out the ingredients No Gluten, Non-GMO, No Soy, No Artificial Color, No Artificial Flavor, No Artificial Sweetener, No Preservatives, No Wheat, No Yeast, No ..read more

Senolytics: Revolutionising the Approach to Healthy Ageing by Targeting Senescent Cells Hallmarks of Ageing 2/12 As the world's population ages, the quest for longevity and a healthier, vibrant life in later years becomes increasingly important. A crucial player in this pursuit is the understanding of senescent cells, often termed 'zombie cells,' and the emerging field of senolytics. These breakthroughs offer promising avenues for enhancing health during ageing. The Science of Ageing and Senescent Cells: Age-related decline in organ function raises questions about cellular efficiency over time ..read more

Hallmarks of ageing: 1/12- Genomic Instability In our "Longevity Insights" series, we're diving deep into the science of ageing, uncovering the vital biological processes that mark the passage of time in our bodies. Each aspect we explore is not just a piece of the ageing puzzle but a fundamental biological process that evolves with age, impacting our tissue and organ function. Our goal? To demystify these complex processes and provide practical biohacks, empowering you to take charge of your health and well-being. By understanding and intervening in these ageing mechanisms, we can potentially ..read more

Hallmarks of ageing: 1/12- Genomic Instability In our "Longevity Insights" series, we're diving deep into the science of ageing, uncovering the vital biological processes that mark the passage of time in our bodies. Each aspect we explore is not just a piece of the ageing puzzle but a fundamental biological process that evolves with age, impacting our tissue and organ function. Our goal? To demystify these complex processes and provide practical biohacks, empowering you to take charge of your health and well-being. By understanding and intervening in these ageing mechanisms, we can potentially ..read more