Entering the golden age for antibody-drug conjugates in gynecologic cancer
Medical Xpress » Chemotherapy
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1d ago
In an editorial, published in Oncoscience titled, "Entering the golden age for antibody-drug conjugates in gynecologic cancer," researchers Michelle Greenman, Blair McNamara, Levent Mutlu, and Alessandro D. Santin from Yale University School of Medicine discuss gynecologic cancers ..read more
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New model could reduce reliance on chemotherapy
Medical Xpress » Chemotherapy
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5d ago
A model co-designed by a professor at Anglia Ruskin University is expected to reduce the need for chemotherapy in up to 38% of breast cancer patients who would previously have been advised to consider the treatment ..read more
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Tisotumab vedotin found efficacious for recurrent cervical cancer
Medical Xpress » Chemotherapy
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1w ago
Second- or third-line treatment with tisotumab vedotin is efficacious for patients with recurrent cervical cancer, according to a study published in the New England Journal of Medicine ..read more
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RNAs may help identify stage II colon cancer patients who could benefit from chemotherapy following surgery
Medical Xpress » Chemotherapy
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1w ago
The decision to treat patients with stage II colon cancer with adjuvant chemotherapy remains controversial. Therefore, there is an urgent need to identify reliable prognostic biomarkers that may be used to identify which patients would benefit from chemotherapy following surgery. In a study investigators have assessed the biomarker potential of RNAs in stage II colon cancer. Their findings appear in The American Journal of Pathology ..read more
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Promising new target discovered in pancreatic cancer could boost chemotherapy and reduce spread
Medical Xpress » Chemotherapy
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1w ago
A molecule called nidogen-2 may be a key driver of pancreatic cancer progression and metastasis, offering a promising new treatment approach for this aggressive cancer, according to a Garvan Institute study ..read more
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Epilepsy drug could keep chemotherapy for stomach cancer working for longer
Medical Xpress » Chemotherapy
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1w ago
Cancer's resistance to chemotherapy could be reversed by targeting lactate—the product that builds up as cancer cells convert nutrients to energy, according to new research published in Nature ..read more
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Physical exercise prevents nerve damage during chemotherapy, sports scientist shows
Medical Xpress » Chemotherapy
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2w ago
Cancer treatments often cause nerve damage that can lead to long-lasting symptoms. Medication has proven ineffective in these cases. A sports scientist at the University of Basel, together with an interdisciplinary team from Germany, has now shown that simple exercises can prevent nerve damage ..read more
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Chemotherapy could disrupt gut microbiome in patients with breast cancer
Medical Xpress » Chemotherapy
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2w ago
Chemotherapy is known to cause behavioral side effects, including cognitive decline. Notably, the gut microbiome communicates with the brain to affect behavior, including cognition ..read more
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3D cell cultures reveal how cancer cells navigate tissue
Medical Xpress » Chemotherapy
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1M ago
Developing chemotherapy drugs against breast cancer is costly, slow, and often inefficient, with more than 95% of screened drug candidates failing in patient trials. A new technique for 3D cell culturing, developed by researchers at Finland's Aalto University, offers unprecedented insight into the spread of cancer cells through tissue. The technique paves the way to improved efficacy in screening for chemotherapy drug candidates, potentially enabling the screening out of non-viable drug candidates much earlier in the process ..read more
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Study shows ivonescimab improves progression-free survival in EGFR+ lung cancer
Medical Xpress » Chemotherapy
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1M ago
For patients with non-small cell lung cancer with the epidermal growth factor receptor (EGFR) variant, ivonescimab plus chemotherapy improves progression-free survival, according to a study published online May 31 in the Journal of the American Medical Association (JAMA) to coincide with the annual meeting of the American Society of Clinical Oncology, held from May 31 to June 4 in Chicago ..read more
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