Insilico Medicine's AI-driven approach yields promising PTPN2/N1 inhibitor for cancer immunotherapy
News Medical » Medicinal Chemistry
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1w ago
In recent years, cancer immunotherapy, exemplified by PD-1 and its ligand PD-L1 blockade, has made remarkable advances ..read more
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New drug candidates show promise to reverse HIV immune evasion
News Medical » Medicinal Chemistry
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1M ago
University of Pittsburgh School of Medicine scientists have identified drug candidates that show promise to reverse the ability of HIV to escape detection by the immune system ..read more
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New compounds show potential to mimic benefits of exercise
News Medical » Medicinal Chemistry
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1M ago
Doctors have long prescribed exercise to improve and protect health. In the future, a pill may offer some of the same benefits as exercise ..read more
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U-M research offers a new path forward in the development of anti-HIV drugs
News Medical » Medicinal Chemistry
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1M ago
A team of University of Michigan researchers has successfully modified a naturally occurring chemical compound in the lab, resulting in advanced lead compounds with anti-HIV activity ..read more
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Researchers forge new path to combat viruses and cancers with helicase inhibitors
News Medical » Medicinal Chemistry
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1M ago
Helicases are enzymes that unwind DNA and RNA. They're central to cellular life, implicated in a number of cancers and infections-;and, alas, extraordinarily difficult to target with drugs ..read more
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Researchers develop precise drugs to target HIV's Nef protein
News Medical » Medicinal Chemistry
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1M ago
A team of University of Michigan researchers has successfully modified a naturally occurring chemical compound in the lab, resulting in advanced lead compounds with anti-HIV activity ..read more
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Rare gene mutations in hereditary Alzheimer's disease disrupt amyloid production, study shows
News Medical » Medicinal Chemistry
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2M ago
A University of Kansas study of rare gene mutations that cause hereditary Alzheimer's disease shows these mutations disrupt production of a small sticky protein called amyloid ..read more
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UB research may offer a more streamlined approach to developing cancer drugs
News Medical » Medicinal Chemistry
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2M ago
Drug discovery can be a frustrating process of trial and error ..read more
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SCIEX’s Jose Castro-Perez Reveals How They're Setting New Standards in Mass Spectrometry
News Medical » Medicinal Chemistry
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2M ago
SCIEX’s Reveals How They're Setting New Standards in Mass Spectrometry at SLAS 2024 ..read more
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Scientists develop 3D-printable gelatin materials for reconstructive and plastic surgery
News Medical » Medicinal Chemistry
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2M ago
Researchers from IOCB Prague and Ghent University have been working on improving the properties of gelatin-based materials, thereby expanding the possibilities of their use mainly in medicine ..read more
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