Nature » Medicinal Chemistry
Nature » Medicinal Chemistry
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Medicinal chemistry deals with the design, optimization, and development of chemical compounds for use as drugs. Read the latest news and research from Nature.com on the topic of Medicinal chemistry. Nature Portfolio is here to serve the research community by publishing its most significant discoveries - findings that advance knowledge and address some of the greatest challenges that we face..
Epigenetic modulation through BET bromodomain inhibitors as a novel therapeutic strategy for progranulin-deficient frontotemporal dementia
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Statine-based peptidomimetic compounds as inhibitors for SARS-CoV-2 main protease (SARS-CoV‑2 Mpro)
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Affinity chromatography reveals direct binding of the GATA4–NKX2-5 interaction inhibitor (3i-1000) with GATA4
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Late-stage meta-C–H alkylation of pharmaceuticals to modulate biological properties and expedite molecular optimisation in a single step
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Targeting the incretin system in obesity and type 2 diabetes mellitus
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Predicting permeation of compounds across the outer membrane of P. aeruginosa using molecular descriptors
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Design, synthesis, biological assessment and molecular modeling studies of novel imidazothiazole-thiazolidinone hybrids as potential anticancer and anti-inflammatory agents
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Spectral characterization of the impact of modifiers and different prepare temperatures on snow lotus medicinal residue-biochar and dissolved organic matter
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Equivariant 3D-conditional diffusion model for molecular linker design
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G protein-coupled receptors (GPCRs): advances in structures, mechanisms, and drug discovery
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