Variants in the WDR44 WD40-repeat domain cause a spectrum of ciliopathy by impairing ciliogenesis initiation
Nature » Polycystic kidney disease
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4M ago
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Deletion of Aurora kinase A prevents the development of polycystic kidney disease in mice
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4M ago
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Polygenic risk alters the penetrance of monogenic kidney disease
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4M ago
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Fibrocystin/Polyductin releases a C-terminal fragment that translocates into mitochondria and suppresses cystogenesis
Nature » Polycystic kidney disease
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6M ago
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Immune-checkpoint inhibition to slow cyst growth
Nature » Polycystic kidney disease
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9M ago
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Atypical splicing variants in PKD1 explain most undiagnosed typical familial ADPKD
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10M ago
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The C-terminal tail of polycystin-1 suppresses cystic disease in a mitochondrial enzyme-dependent fashion
Nature » Polycystic kidney disease
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1y ago
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The cilia mechanosensation debate gets (bio)physical
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1y ago
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Primary cilia sense glutamine availability and respond via asparagine synthetase
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1y ago
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Pathological consequences of DNA damage in the kidney
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1y ago
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