The liver, the largest organ of the body, is known to store nutrients, manufacture bile to digest foods, filter and remove harmful materials from the blood. But sometimes, things go wrong and liver cells turn deadly leading to liver cancer. It is essential to take care of your liver health and take notice of any abnormal functioning of the liver, as it is the vital organ for your survival. You may survive with one kidney but you can’t live without a liver. Only early detection can help to treat it successfully. Here is some essential information you need to know about liver cancer. What is li ..read more

Scientists at University of Birmingham have found that the combination of cholesterol-lowering drug, bezafibrate, and a contraceptive steroid, medroxyprogesterone acetate can be effective to treat several blood cancer such as acute myelogenous leukemia (AML), chronic lymphocytic leukaemia (CLL) and non-Hodgkin’s lymphoma. This study was conducted to determine the mechanism of action of combination of bezafibrate and medroxyprogesterone acetate (BaP) and was published in the ‘Cancer Research’ Journal. The effect of this drug combination was investigated in AML and Burkitt’s lymphoma cells (BL ..read more

A new clinical trial published in the ‘Journal of Clinical Oncology’ reported that adavosertib can significantly reduce the tumor regrowth and improve survival rates in metastatic colorectal cancer patients. In this study, patients with metastatic colorectal cancer who have mutations in TP53 and RAS genes were included. The patients who were stable or responded after 16 weeks of chemotherapy were randomly divided in adavosertib and active monitoring groups. Adavosertib, 250 or 300 mg was administered once orally on days 1-5 and days 8-12 of a 3-week cycle. Progression free survival was evaluat ..read more

A recent study published in 'Medicine & Science in Sports & Exercise reported that myokines, a type of peptide released during exercise, can help to reduce and suppress tumour growth in patients with prostate cancer. This study enrolled ten prostate cancer patients who had received androgen deprivation therapy (ADT) and underwent a 12-week exercise-based intervention. This intervention included protein supplementation, supervised resistance training and self-directed aerobic exercises. Fasting blood was collected to evaluate serum myokines levels, and their effect on the growth of pro ..read more

Based on the findings of open-label, multi center, single-arm phase 2 trial, the Food and Drug Administration (FDA) has granted accelerated approval to Tisotumab vedotin for treating patients with metastatic or recurrent cervical cancer with disease progression who were either on treatment or after chemotherapy. In this study, a total of 101 adult females with metastatic or recurrent cervical cancer were enrolled. In addition, the patients who had received treatment with no more than two prior systemic regimens in the recurrent/metastatic settings, with at least one initial platinum-based che ..read more

Do you know? Every 1 in 3 women who have battled breast cancer can see its return, referred to as metastatic breast cancer. This type of breast cancer is deadly and can only be battled by early detection and treatment. October 13 is the Metastatic Breast Cancer Awareness Day. Unfortunately, the chances are good that people are not aware of this cancer, and it is the right time to gain knowledge about this cancer and how it can be treated and prevented through early screening. As more and more people become aware, the fight against this cancer becomes more straightforward, which is helpful to ..read more

Mushrooms often addressed as the ‘elixir of life’ and ‘foods for the Gods’ are the powerhouse of health boosting nutrients. They are the richest source of proteins, fibre, vitamins (D, B1, B12, C and E), potassium, phosphorus and selenium. Not just nutrients, they are also packed with phenolic compounds, carotenoids, polysaccharides and indoles which show antioxidant, anti-inflammatory and anticancer properties. These beneficial properties help to reduce the risk of inflammatory diseases, allergies, heart diseases, hypertension and cancer. As functional medicine and holistic nutrition are mai ..read more

Jackfruit is an exotic anti-cancer fruit which is usually grown in tropical areas of Asian countries. In India, it is specifically grown in South India and is popular as a meat substitute among vegetarians due to its texture. It is rich in macronutrients such as carbohydrates, proteins, vitamins, minerals and various phytonutrients. Both the flesh and seeds of unripe jackfruit are consumed in boiled forms and curries whereas the flesh of fully ripe fruit can be eaten directly or consumed in the form of juices. Several parts of jackfruit plants such as leaves, bark, seeds and fruits have been ..read more

Cancer has been the leading cause of deaths across the globe. Limited efficacy of conventional treatments such as chemotherapy, and a higher relapse rate poses a major challenge in cancer treatment and demands the development of novel therapies such as CAR T-cell therapy in management of cancer. After several decades of painstaking research, the development of immunotherapy has helped to reach a tipping point in the field of cancer. Among immunotherapy, Chimeric antigen receptor (CAR) T-cell therapy has emerged as a revolutionary treatment for cancer. CAR T-cell therapy is a fairly novel thera ..read more

Cancers are the abnormal growth of cells (mass or tumour) in the body mostly caused by poor lifestyle choices or environmental risk factors in adults unlike those in children. Childhood cancers are rare and are caused majorly due to alterations in the genes or DNA in the early formative years of a child. As per the estimates of the World Health Organization (WHO), about 400 000 children and teenagers aged between 0-19 years old are diagnosed with cancer every year. But, the most distressing is only 15 to 45% of children with cancer are curable in the low- and middle-income countries (LMICs) co ..read more