Human microbiome Safety and efficacy of faecal microbiota transplantation in patients with mild to moderate Parkinson’s disease (GUT-PARFECT): a double-blind, placebo-controlled, randomised, phase 2 trial – Anout Bruggeman – eClinicalMedicine Implications of intestinal microecology and immune function alterations for immunotherapy outcomes in advanced unresectable lung adenocarcinoma – Shuang He – Clinical Respiratory Journal Recipient microbiome-related ..read more

Human and General Microbiome Genome Analysis of Epsilon CrAss-like Phages – Igor V Babkin – Viruses Cervical microbiota dysbiosis associated with high-risk Human Papillomavirus infection – Natalia Zeber-Lubecka – PloS ONE Association of the trimethylamine N-oxide with cardiovascular risk and vascular alterations in middle-aged patients with risk factors for cardiovascular diseases – Natalia Spasova ..read more

General microbiome A naturally isolated symbiotic bacterium suppresses flavivirus transmission by Aedes mosquitoes – Science  Gut Microbiome Gut microbial metabolism of 5-aminosalicylic acid in inflammatory bowel disease – Gut Smoking-related Lactobacillus and immune cell infiltration in colorectal cancer: evidence from a population-based study – Gut.  Gut microbiota dysbiosis contributes to depression-like behaviors via hippocampal NLRP3-mediated ..read more

Human and General Microbiome Mechanoelectronic stimulation of autologous extracellular vesicle biosynthesis implant for gut microbiota modulation – Shuangshuang Wan – Nature Communications Oral bacterial insights from a comparative study between healthy and comorbid diseased human individuals – Anand Ravichandran – Microbial Pathogenesis Dietary fiber guar gum-induced shift in gut microbiota metabolism and intestinal immune activity ..read more

Good morning and welcome to another MicrobiomeDigest! Did you know that one group of scientists is using video games to crowdsource puzzle solutions to improve microbiome research? What a neat way to approach citizen science! On deck today we have a study about pesticide exposure and the gut microbiome, a review of the emerging field ..read more

Human and General Microbiome Human fecal alpha-glucosidase activity and its relationship with gut microbiota profiles and early stages of intestinal mucosa damage – Sergio Ruiz-Saavedra – Anaerobe The microbiota drives diurnal rhythms in tryptophan metabolism in the stressed gut – Cassandra E Gheorghe – Cell Reports Alterations in gut microbiota contribute to cognitive deficits induced ..read more

Today’s digest features human gut microbiome studies on dietary fiber and fasting glucose, ocean microbiome, pangenome approaches, and more. See you at #MVIF! Oral microbiome Saliva sampling method influences oral microbiome composition and taxa distribution associated with oral diseases – Cristian Roca – PlosOne Gut microbiome Changes in the intestinal microbiota of individuals with non-alcoholic ..read more

Human and General Microbiome The secreted protein Amuc_1409 from Akkermansia muciniphila improves gut health through intestinal stem cell regulation – Eun-Jung Kang – Nature Communications A universal plasma metabolites-derived signature predicts cardiovascular disease risk in MAFLD – Zhonglin Li – Atherosclerosis Oral-gut microbial transmission promotes diabetic coronary heart disease – Yiwen Li – Cardiovascular Diabetology ..read more

Human Microbiome The effects of antibiotic exposures on the gut resistome during hematopoietic cell transplantation in children – Sarah M Heston – Gut Microbes Clinically used broad-spectrum antibiotics compromise inflammatory monocyte-dependent antibacterial defense in the lung – Patrick J Dörner – Nature Communications The gut metabolite indole-3-propionic acid activates ERK1 to restore social function and ..read more

Human Microbiome A host-microbiota interactome reveals extensive transkingdom connectivity – Nicole D Sonnert – Nature A distinct Fusobacterium nucleatum clade dominates the colorectal cancer niche – Martha Zepeda-Rivera – Nature Cluster-specific associations between the gut microbiota and behavioral outcomes in preschool-aged children – Marcel van de Wouw – Microbiome Association between oral and fecal microbiome ..read more