Journal of Allergy and Clinical Immunology on Feedspot

Population descriptors in asthma and allergy research: Time to re-group

Journal of Allergy and Clinical Immunology

by Carole Ober, Christine L.M. Joseph, John Novembre

23h ago

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β1 integrin-mediated mast cell immune-surveillance of blood vessel content

Journal of Allergy and Clinical Immunology

by Kristina Link, Lina Muhandes, Anastasia Polikarpova, Tim Lämmermann, Michael Sixt, Reinhard Fässler, Axel Roers

3d ago

Immunoglobulin E, IgE)-mediated degranulation of mast cells, MCs) provides rapid protection against environmental hazards, including animal venoms. A fraction of tissue-resident MCs intimately associates with blood vessels. These perivascular MCs were reported to extend projections into the vessel lumen and to be the first MCs to acquire intravenously injected IgE, suggesting that IgE loading of MCs depends on their vascular association ..read more

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Preparing Patients for Oral Immunotherapy (PPOINT): International Delphi consensus for procedural preparation and consent

Journal of Allergy and Clinical Immunology

by Douglas P. Mack, Timothy E. Dribin, Paul J. Turner, Richard L. Wasserman, Mariam A. Hanna, Marcus Shaker, Mimi L.K. Tang, Pablo Rodríguez del Río, Brad Sobolewski, Elissa M. Abrams, Aikaterini Anagnostou, Stefania Arasi, Sakina Bajowala, Philippe Bégin, Scott B. Cameron, Edmond S. Chan, Sharon Chinthrajah, Andrew T. Clark, Paul Detjen, George du Toit, Motohiro Ebisawa, Arnon Elizur, Jeffrey M. Factor, Justin Greiwe, Jonathan O’B Hourihane, Sarah W. Hughes, Douglas H. Jones, Antonella Muraro, Anna Nowak-Wegrzyn, Nandinee B. Patel, Amy M. Scurlock, Atul N. Shah, Sayantani B. Sindher, Stephen Tilles, Brian P. Vickery, Julie Wang, Hugh H. Windom, Matthew Greenhawt

1w ago

Despite the promise of oral immunotherapy (OIT) to treat food allergies, this procedure is associated with potential risk. There is no current agreement about what elements should be included in the preparatory or consent process ..read more

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A Practical Guide for Implementing Omalizumab Therapy for Food Allergy

Journal of Allergy and Clinical Immunology

by Thomas B. Casale, Alessandro Fiocchi, Matthew Greenhawt

1w ago

The recent approval of omalizumab for the treatment of IgE-mediated food allergy is an important step forward for the millions of food allergy patients in the US. Through the depletion of circulating IgE and the subsequent reduction of FCεR1 on key effector cells, patients increase their tolerance to food allergens. However, omalizumab does not permit patients to eat foods that they are allergic to with impunity. Rather, it protects them from most accidental exposures. In addition, omalizumab does not cure food allergy and has not demonstrated true immunomodulation ..read more

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Identification of pyruvic and maleic acid as potential markers for disease activity and prognosis in chronic urticaria

Journal of Allergy and Clinical Immunology

by Xingxing Jian, Guixue Hou, Liqiao Li, Zhuo Diao, Yingfang Wu, Jiayi Wang, Lu Xie, Cong Peng, Liang Lin, Jie Li

1w ago

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Downregulation of otulin induces inflammasome activation in neutrophilic asthma

Journal of Allergy and Clinical Immunology

by Quang Luu Quoc, YeJi Kim, Gunwoo Park, Thi Bich Tra Cao, Youngwoo Choi, Yong Hwan Park, Hae-Sim Park

1w ago

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Addressing Health Disparities and Transitions of Care in EGIDs

Journal of Allergy and Clinical Immunology

by Mirna Chehade, Elizabeth T. Jensen, Benjamin L. Wright

1w ago

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Targeting Inhibitory Siglec-3 to Suppress IgE-Mediated Human Basophil Degranulation

Journal of Allergy and Clinical Immunology

by Suzanne M. Barshow, Maidul Islam, Scott Commins, Matthew S. Macauley, James C. Paulson, Michael D. Kulis

1w ago

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On Mentoring and Being Mentored- a Lifetime Journey and Legacy

Journal of Allergy and Clinical Immunology

by Wanda Phipatanakul

1w ago

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Corrigendum

Journal of Allergy and Clinical Immunology

by

1w ago

With regard to the article in the April 2022 issue entitled “Monogenic early-onset lymphoproliferation and autoimmunity: Natural history of STAT3 gain-of-function syndrome” (J Allergy Clin Immunol 2022;151:1081-95), author Eleonora Gambineri would like to update her affiliations to read: Department of NEUROFARBA, Section of Children's Health, University of Florence, Florence, Italy; and Centre of Excellence, Division of Pediatric Oncology/Hematology, Meyer Children’s Hospital IRCCS, Florence, Italy ..read more

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