Vitamin C stabilizes n-type organic semiconductors
Nature Materials
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2d ago
Nature Materials, Published online: 11 July 2024; doi:10.1038/s41563-024-01939-4 The instability of n-type organic semiconductors in air is a long-standing challenge in organic electronics. Now, a strategy based on the use of vitamin C is developed to stabilize organic semiconductors. Vitamin C scavenges reactive oxygen species and inhibits their generation, improving the performance and stability of organic semiconductors and their electronic devices ..read more
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Inulin-gel-based oral immunotherapy remodels the small intestinal microbiome and suppresses food allergy
Nature Materials
by Kai Han, Fang Xie, Olamide Animasahun, Minal Nenwani, Sho Kitamoto, Yeji Kim, May Thazin Phoo, Jin Xu, Fulei Wuchu, Kehinde Omoloja, Abhinav Achreja, Srinadh Choppara, Zhaoheng Li, Wang Gong, Young Seok Cho, Hannah Dobson, Jinsung Ahn, Xingwu Zhou, Xuehui Huang, Xinran An, Alexander Kim, Yao Xu, Qi Wu, Soo-Hong Lee, Jessica J. O’Konek, Yuying Xie, Yu Leo Lei, Nobuhiko Kamada, Deepak Nagrath, James J. Moon
5d ago
Nature Materials, Published online: 08 July 2024; doi:10.1038/s41563-024-01909-w An oral inulin allergen gel restores the microbiota of allergic mice and suppresses undesired immune responses to achieve allergen-specific oral tolerance, effectively overcoming food allergy ..read more
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Quantifying mechanical forces during vertebrate morphogenesis
Nature Materials
by Eirini Maniou, Silvia Todros, Anna Urciuolo, Dale A. Moulding, Michael Magnussen, Ioakeim Ampartzidis, Luca Brandolino, Pietro Bellet, Monica Giomo, Piero G. Pavan, Gabriel L. Galea, Nicola Elvassore
1w ago
Nature Materials, Published online: 05 July 2024; doi:10.1038/s41563-024-01942-9 Hydrogel force sensors directly bioprinted into embryonic tissues quantify the forces driving tissue remodelling and reveal the existence of mechanisms that counteract tissue morphogenesis ..read more
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Synthetic extremophiles via species-specific formulations improve microbial therapeutics
Nature Materials
by Miguel Jimenez, Johanna L’Heureux, Emily Kolaya, Gary W. Liu, Kyle B. Martin, Husna Ellis, Alfred Dao, Margaret Yang, Zachary Villaverde, Afeefah Khazi-Syed, Qinhao Cao, Niora Fabian, Joshua Jenkins, Nina Fitzgerald, Christina Karavasili, Benjamin Muller, James D. Byrne, Giovanni Traverso
1w ago
Nature Materials, Published online: 05 July 2024; doi:10.1038/s41563-024-01937-6 A high-throughput screen of substances generally recognized as safe identifies species-specific materials that stabilize live microbial therapeutics as powders, making them robust to pharmaceutical manufacturing workflows ..read more
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Into the attosecond era
Nature Materials
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1w ago
Nature Materials, Published online: 05 July 2024; doi:10.1038/s41563-024-01949-2 The generation of attosecond pulses has opened the door to probing electron dynamics at sub-atomic scales. Beyond atomic physics, this field is envisioned to also have a decisive impact on condensed-matter physics, chemistry and biology ..read more
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Engineered matrices reveal stiffness-mediated chemoresistance in patient-derived pancreatic cancer organoids
Nature Materials
by Bauer L. LeSavage, Daiyao Zhang, Carla Huerta-López, Aidan E. Gilchrist, Brad A. Krajina, Kasper Karlsson, Amber R. Smith, Kremena Karagyozova, Katarina C. Klett, Michelle S. Huang, Christopher Long, Gernot Kaber, Christopher M. Madl, Paul L. Bollyky, Christina Curtis, Calvin J. Kuo, Sarah C. Heilshorn
1w ago
Nature Materials, Published online: 04 July 2024; doi:10.1038/s41563-024-01908-x Patient-derived pancreatic cancer organoids grown in engineered matrices acquire chemoresistance due to the increased expression of drug efflux transporters, promoted by CD44 receptor interactions with hyaluronan in the stiffer tumoural matrix ..read more
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Lipid discovery for mRNA delivery guided by machine learning
Nature Materials
by Roy van der Meel, Francesca Grisoni, Willem J. M. Mulder
1w ago
Nature Materials, Published online: 02 July 2024; doi:10.1038/s41563-024-01934-9 Combining machine learning with high-throughput synthesis expedites ionizable cationic lipid development for nanoparticle-based messenger RNA delivery ..read more
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Unfolding a death signal to treat rheumatoid arthritis
Nature Materials
by Marcus E. Peter, Maartje M. C. Bastings
1w ago
Nature Materials, Published online: 02 July 2024; doi:10.1038/s41563-024-01936-7 A pH-activatable DNA origami nanostructure with geometrically patterned CD95 ligands reverses symptoms in a mouse model of rheumatoid arthritis without apparent side effects ..read more
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The need for standardizing fatigue data reporting
Nature Materials
by Zhiping Xu, Zian Zhang
1w ago
Nature Materials, Published online: 02 July 2024; doi:10.1038/s41563-024-01929-6 The need for standardizing fatigue data reporting ..read more
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Writing a magnetic whirl on multiferroics
Nature Materials
by Masahito Mochizuki
1w ago
Nature Materials, Published online: 02 July 2024; doi:10.1038/s41563-024-01923-y Researchers have demonstrated that skyrmion-like topological spin textures can be created in a controlled manner via the local application of an electric field with a tip electrode on a multiferroic BiFeO3 thin film ..read more
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