A large randomised trial conducted at Tampere University and the University of Helsinki, Finland, shows that a new three-step prostate cancer screening method can find a considerable number of aggressive cancers. Population-level screening programmes have not been launched in most countries including Finland. The ProScreen trial coordinated by Tampere University and the University of Helsinki ..read more

Mutations are the changes in the DNA that gradually occur in human cells as they replicate, and the organism grows and ages. Some of these changes, particularly when they occur in genes, can be instrumental during the development of cancer. Therefore, it is important to differentiate changes that have the potential of being relevant for ..read more

New research from the University of Eastern Finland sheds light on the significance of the glucocorticoid receptor in drug-resistant prostate cancer, showing that the development of drug resistance could be prevented by limiting the activity of coregulator proteins. Glucocorticoids regulate vital biological processes by affecting gene encoding through a DNA-binding transcription factor, namely the glucocorticoid ..read more

A new lab assay developed by researchers at Fred Hutch Cancer Center, USA, could make diagnosis and treatment of small-cell lung cancer and non-small cell lung cancer easier. The blood-based test, also called a “liquid biopsy,” can detect differences between types of lung cancer by examining patterns in cell-free tumour DNA in blood samples. It’s ..read more

A video designed to educate Black men about prostate cancer resulted in 97% of surveyed participants acknowledging that Black men are at a higher risk of this disease and 93% saying they would get screened, according to a study presented at the American Association for Cancer Research (AACR) Annual Meeting 2024, held April 5-10. Black men have ..read more

Researchers have developed a functional precision medicine approach that targets cancer by combining genetic testing with a new way to test individual drugs on tumour samples. The results of the clinical study were published  in Nature Medicine. This combined approach, developed by Florida International University cancer researcher Diana Azzam, was used successfully for the first ..read more

Researchers have discovered how the mechanical properties of tumours can prime cancer cells to better survive their spread to other organs. A metabolic ‘survival switch’ controlled by the stiffness of triple-negative breast tumours can significantly influence how successfully their cancerous cells spread to other organs, according to new findings from the Garvan Institute of Medical ..read more

Researchers have identified new variations in neuroblastoma that could lead to a more accurate prognosis and better-targeted treatments for this devastating childhood cancer. A study published in the British Journal of Cancer reveals three new subgroups of the most common type of neuroblastoma, each with different genetic traits, expected outcomes, and distinguishing features that offer clues as ..read more

Melanoma is the deadliest form of skin cancer. With global incidence rates rising, new, more effective treatments are necessary to alleviate the health burden of the disease. Important advances in recent years include doctors using genetic tests to look for specific mutations they can target for more personalised, effective treatment. Around 1 in 2 melanoma ..read more

A research team from the National University of Singapore (NUS) has unearthed new findings which may help explain the connection between cancer risk and poor diet, as well as common diseases like diabetes, which arise from poor diet. The insights gained from this study hold promise for advancing cancer prevention strategies aimed at promoting healthy ..read more