A major impediment to treating the deadly brain cancer glioblastoma has been that the most potent chemotherapy can’t permeate the blood-brain barrier to reach the aggressive brain tumour. But now Northwestern Medicine scientists report results of the first in-human clinical trial in which they used a novel, skull-implantable ultrasound device to open the blood-brain barrier ..read more

Cyteph, a spin-out biotechnology company from QIMR Berghofer Medical Research Institute, has been awarded a $1.5m grant via the CUREator incubator. This grant signals an official launch milestone for the Company, supporting its imminent plan to conduct a phase 1 clinical trial for its lead candidate CYT-101 in recurrent glioblastoma multiforme (GBM) patients. Under the ..read more

In a recent study, current smoking and vaping were associated with a higher burden of symptoms among adult cancer survivors, but these symptoms were not related to survivors’ desire to quit smoking. The findings are published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society. Continued smoking after a cancer diagnosis lowers survival rates ..read more

According to the latest Australian Institute for Health and Welfare cancer in adolescents and young adults in Australia report, which reviewed national cancer outcomes for people aged 15-24 years, the improvement in survival was most dramatic for blood cancers where five-year survival had increased from 64 per cent in the 1980’s to 91 per cent in ..read more

Peter Mac researchers working on cures for breast cancer have just been awarded more than $4.5 million in grants from the National Breast Cancer Foundation. Each day 57 women are diagnosed with breast cancer and it remains the second largest cause of cancer death in women. In a quest to change outcomes for breast cancer ..read more

Despite our understanding of nutrition expanding remarkably in recent times, few aspects of our diet continue to confuse and divide the experts like nitrate. For a long time nitrate has been viewed warily, with previous research showing it could potentially be linked to causing cancer. However, subsequent research has revealed dietary nitrate also has various ..read more

A pioneering radiotherapy treatment developed at Peter Mac is emerging as a new treatment option for cancer that has spread to the lungs, following exciting results in a recent study. Long-term survival data is now available from the SAFRON II clinical trial, which involved patients with up to three spots of cancer that had metastasized ..read more

Inflammatory fatty liver disease (NASH, non-alcoholic steatohepatitis ) and the resulting liver cancer are driven by autoaggressive T cells. Scientists from the German Cancer Research Center (DKFZ) now show what is behind this destructive behaviour. In both mice and humans with NASH, they found increased numbers of activated B cells in the gastrointestinal tract. The ..read more