ORGANIC CHEMISTRY SELECT
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A site by Dr Anthony Melvin Crasto, world drug tracker for helping organic chemists with websites, trying to get information at one place, easy picks for users. million hits on google, purely academic, non commercial and free from advertisements, pushing boundaries, world acclamation for efforts.
ORGANIC CHEMISTRY SELECT
1y ago
New Drug Approvals
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Anthony Crasto | Advisor | +91 ..read more
ORGANIC CHEMISTRY SELECT
1y ago
New Drug Approvals
‘Top 10 Prominent & Great Personalities of the year 2022’ campaign by Fame Finders.
Feeling great to be selected in the ‘Top 10 Prominent & Great Personalities of the year 2022’ campaign by Fame Finders. It is an online campaign to honour inspiring personalities and feature them in the upcoming edition of the top news sites, including – Deccan Chronicle/Asian Age/Deccan Herald, ANI, Zee5, Latestly, Lokmat Times, DailyHunt, Google News, JioNews, MSN and 70+ sites.Jan 16 2023
View original post ..read more
ORGANIC CHEMISTRY SELECT
2y ago
New Drug Approvals
ARIMOCLOMOL
アリモクロモル;
Formula
C14H20ClN3O3
Exact mass
313.1193
Mol weight
313.7799
CAS289893-25-0
289893-26-1 (Arimoclomol maleate);
INN 8300
N-[(2R)-2-hydroxy-3-piperidin-1-ylpropoxy]-1-oxidopyridin-1-ium-3-carboximidoyl chloride
BRX 220
Arimoclomol maleate is in a phase III clinical trials by Orphazyme for the treatment of Niemann-Pick disease type C (NP-C). It is also in phase II clinical studies for the treatment of amyotrophic lateral sclerosis (ALS).
Arimoclomol(INN; originally codenamedBRX-345, which is a citrate salt formulation ofBRX-220) is an experiment ..read more
ORGANIC CHEMISTRY SELECT
2y ago
New Drug Approvals
Lansoprazole
Molecular FormulaC16H14F3N3O2S
Average mass369.362 Da
Lansoprazole, AG-1749, ABT-006, CG-4801, A-65006, Ogast, Lanzor, Lanzo, Agopton, Opiren, Bamalite, Takepron, Lansox, Lansox, Ogastro, Monolitum, Prevacid, Zoton103577-45-3[RN]
1H-Benzimidazole, 2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-
лансопразол[Russian][INN],لانسوبرازول[Arabic][INN],兰索拉唑[Chinese][INN]
CAS Registry Number:103577-45-3
CAS Name:2-[[[3-Methyl-4-(2,2,2-trifluoro-ethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole
Additional Names:2-(2-benzimidazolylsulfinylmeth ..read more
ORGANIC CHEMISTRY SELECT
2y ago
New Drug Approvals
MAX 40279,EX-A4057
Max 4; MAX-40279; MAX-40279-001; MAX-40279-01
UNII-DL772G3NN7
2070931-57-4
C22H23FN6OS,438.5
7-(4-fluoro-2-methoxyphenyl)-6-methyl-N-(1-piperidin-4-ylpyrazol-4-yl)thieno[3,2-d]pyrimidin-2-amine
Thieno[3,2-d]pyrimidin-2-amine, 7-(4-fluoro-2-methoxyphenyl)-6-methyl-N-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-
7-(4-FLUORO-2-METHOXYPHENYL)-6-METHYL-N-(1-(PIPERIDIN-4-YL)-1H-PYRAZOL-4-YL) THIENO (3,2-D)PYRIMIDIN-2-AMINE SEMI-FUMARATE CAS2388506-43-0
7-(4-Fluoro-2-methoxyphenyl)-6-methyl-N-[1-(4-piperidinyl)-1H-pyrazol-4-yl]thieno[3,2-d]pyrimidin-2-amine
Originat ..read more
ORGANIC CHEMISTRY SELECT
3y ago
New Drug Approvals
Lurbinectedin
(1’R,6R,6aR,7R,13S,14S,16R)-5-(Acetyloxy)-2′,3′,4′,6,6a,7,9′-decahydro-8,14-dihydroxy-6′,9-dimethoxy-4,10,23-trimethyl-spiro(6,16-(epithiopropaneoxymethano)-7.13-imino-12H-1,3-dioxolo[7,8]soquino[3,2-b][3]benzazocine-20,1′-[1H]pyrido[3,4-b]indol]-19-one
Molecular Weight
784.87
Formula
C41H44N4O10S
CAS No.
497871-47-3 (Lurbinectedin);
Chemical Name
Spiro[6,16-(epithiopropanoxymethano)-7,13-imino-12H-1,3-dioxolo[7,8]isoquino[3,2-b][3]benzazocine-20,1′-[1H]pyrido[3,4-b]indol]-19-one, 5-(acetyloxy)-2′,3′,4′,6,6a,7,9′,13,14,16-decahydro-8,14-dihydroxy-6 ..read more
ORGANIC CHEMISTRY SELECT
5y ago
New Drug Approvals
AK-3280
AK 3280; GDC3280; RG 6069
C19 H15 F3 N4 O2, 388.34
CAS 1799412-33-1
4H-Benzimidazol-4-one, 1,5-dihydro-1-methyl-7-(1-methyl-1H-pyrazol-4-yl)-5-[4-(trifluoromethoxy)phenyl]-
Ci8Hi4N502F3, mass 389.3 g/mol),
ROCHE,
Ark Biosciences , under license from Roche , is developing AK-3280, an antifibrotic agent, for the potential oral treatment of IPF. In July 2018, Ark intended to further clinical development of the drug, for IPF. In June 2019, a phase I trial was planned in Sweden.
Originator Genentech
Mechanism of Action Undefined mechanism
Phase I Inters ..read more
ORGANIC CHEMISTRY SELECT
5y ago
New Drug Approvals
Thiotepa, チオテパ
Use:antineoplastic, alkylating agent
Chemical name:1,1′,1”-phosphinothioylidynetrisaziridine
Formula:C6H12N3PS
MW:189.22 g/mol
CAS:52-24-4
EINECS:200-135-7
LD50:14500 μg/kg (M, i.v.); 38 mg/kg (M, p.o.);
9400 μg/kg (R, i.v.)
Aziridine, 1,1′,1”-phosphinothioylidynetris-
Aziridine, 1-[bis(1-aziridinyl)phosphinothioyl]-
N,N’,N”-Triethylenethiophosphoramide
Phosphorothioic tri(ethyleneamide)
SZ2975000
T3NTJ APS&- AT3NTJ&- AT3NTJ [WLN]
Thiofozil
Thiotef
1,1′,1”-Phosphorothioyltriaziridine
JAPAN APPROVED, Rethio, PMDA, 2019/3/26 ..read more
ORGANIC CHEMISTRY SELECT
5y ago
New Drug Approvals
SRT-1720 diHCl
CAY10559
CAS: 1001645-58-4 (di HCl) , 925434-55-5 (free base) 1001645-58-4 (HCl)
Chemical Formula: C25H25Cl2N7OS
Molecular Weight: 542.483
Elemental Analysis: C, 55.35; H, 4.65; Cl, 13.07; N, 18.07; O, 2.95; S, 5.91
SRT-1720 HCl, SRT-1720 hudrochloride; SRT1720; SRT-1720; SRT 1720; CAY10559; CAY-10559; CAY 10559; SIRT-1933; SIRT 1933; SIRT1933.
N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazol-6-yl)phenyl)quinoxaline-2-carboxamide dihydrochloride
Molecular FormulaC25H23N7OSAverage mass469.561 DaSRT-1720, also known as CAY10559 and is a drug d ..read more