Clinical Epigenetics
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Encompassing the broad spectrum of epigenetics research from basic research to innovations in therapeutic treatments, Clinical Epigenetics is a top tier, open-access journal devoted to the study of epigenetic principles and mechanisms as applied to human development, disease, diagnosis, and treatment. The journal particularly welcomes submissions involving clinical trials, translational research,..
Clinical Epigenetics
23h ago
CSLCs(Cancer stem cell-like cells), which are central to tumorigenesis, are intrinsically influenced by epigenetic modifications. This study aimed to elucidate the underlying mechanism involving the DNMT1/miR ..read more
Clinical Epigenetics
23h ago
The polycomb group (PcG) comprises a set of proteins that exert epigenetic regulatory effects and play crucial roles in diverse biological processes, ranging from pluripotency and development to carcinogenesis ..read more
Clinical Epigenetics
1w ago
The study of biological age acceleration may help identify at-risk individuals and reduce the rising global burden of age-related diseases. Using DNA methylation (DNAm) clocks, we investigated biological aging ..read more
Clinical Epigenetics
1w ago
Diabetic cardiomyopathy (DCM) is a critical complication that poses a significant threat to the health of patients with diabetes. The intricate pathological mechanisms of DCM cause diastolic dysfunction, follo ..read more
Clinical Epigenetics
1w ago
The intriguing connection between selenium and cancer resembles a captivating puzzle that keeps researchers engaged and curious. While selenium has shown promise in reducing cancer risks through supplementatio ..read more
Refining risk prediction in pediatric acute lymphoblastic leukemia through DNA methylation profiling
Clinical Epigenetics
2w ago
Acute lymphoblastic leukemia (ALL) is the most prevalent cancer in children, and despite considerable progress in treatment outcomes, relapses still pose significant risks of mortality and long-term complicati ..read more
Clinical Epigenetics
2w ago
miR-182 promoter hypermethylation frequently occurs in various tumors, including acute myeloid leukemia, and leads to low expression of miR-182. However, whether adult acute lymphocyte leukemia (ALL) cells hav ..read more
Clinical Epigenetics
2w ago
The unknown tissue of origin in head and neck cancer of unknown primary (hnCUP) leads to invasive diagnostic procedures and unspecific and potentially inefficient treatment options for patients. The most commo ..read more
Clinical Epigenetics
3w ago
In this study, a novel restriction enzyme (RE) digestion-based droplet digital polymerase chain reaction (ddPCR) assay was designed for cg005575921 within the AHRR gene body and compared with matching results obt ..read more
Clinical Epigenetics
3w ago
Epigenetic Scores (EpiScores) for blood protein levels have been associated with disease outcomes and measures of brain health, highlighting their potential usefulness as clinical biomarkers. They are typicall ..read more