PKD: Tolvaptan Study of Impact on Quality of Life
PKD News Blog
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4y ago
PKD Treatment From healio.com Tolvaptan showed no impact on QoL for patients with autosomal-dominant polycystic kidney disease Treatment with tolvaptan did not appear to affect health-related quality of life for Swiss patients with autosomal-dominant polycystic kidney disease, according to study results. “Recently, tolvaptan, an orally active, non-peptide selective arginine vasopressin V2R antagonist has been approved for the treatment of [autosomal-dominant polycystic kidney disease] ADPKD in many countries, including Switzerland,” Manuel A. Anderegg, MD, PhD, of Bern University Hospital ..read more
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Portable Artificial Kidney Breakthrough Trials, Comparison of Dialysis Methods for Patient Survival
PKD News Blog
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4y ago
Dialysis  From South China Morning Post, by Minghe Hu in Beijing and Coco Feng Singaporean start-up’s portable ‘kidney’ could shrink dialysis machines, giving patients their freedom back AWAK chief executive Suresha Venkataraya showcases the wearable artificial kidney in Beijing in December 2019. Photo: SCMP/ Coco Feng For the past seven years, 70-year-old Singaporean Julia Lee has rarely travelled overseas. Her most recent trip was one night away, in neighbouring Malaysia. Since being diagnosed with kidney disease, Lee has spent 10 hours each day hooked up to a 20-kilogram machine ..read more
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ADPKD Patients Needed for Study, New Kidney Donation Rules, Perfect Match, Medicare Drug Policy Creates Transplant Problem
PKD News Blog
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4y ago
Kidney Donation From PKD Foundation, Blog, by Alexis Denny, Director of Government Affairs Understanding new rules and regulations around kidney donation — Part One In 2019, the U.S. Department of Health and Human Services (HHS) took major steps to increase the availability of organs for the 113,000 Americans on waitlists for lifesaving organ transplants — 20 of whom die each day. In the July Executive Order (EO) from President Trump, the Centers for Medicare & Medicaid Services (CMS) proposed changes in organ procurement and organizational accountability. On December 18, 2019, Alex Azar ..read more
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PKD Treatment: Octreotide-LAR, Kidney Swaps Revolution, Artificial Kidneys Milestone, Dialysis Patients Panic, Organ on a Chip Testing
PKD News Blog
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4y ago
PKD Treatment From MDMag, by Kenny Walter Octreotide-LAR Delays Cyst Growth in ADPKD Patients Octreotide-LAR treatment could be beneficial to patients suffering from autosomal dominant polycystic kidney disease (ADPKD). In a poster presented at the American Society of Nephrology (ASN) Kidney Week in Washington, D.C., investigators, led by Satyanarayana Vaidya, MD, Emory School of Medicine, evaluated the efficacy of Octreotide-LAR on disease progression based on a meta-analysis of published literature across all stages of chronic kidney disease due to ADPKD. The team identified all placeb ..read more
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ADPKD Patients Needed: ACT Alert, Preventing Blood Clots During Dialysis, Cost of Kidney Transplant Surgery
PKD News Blog
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4y ago
Accelerating Clinical Trials From PKD Foundation ADPKD patients needed for pravastatin study We are conducting a research study in adults with ADPKD to determine if treatment with a statin (pravastatin) will decrease cyst growth and slow renal function decline.  The study plans to enroll up to 200 people, age 25-60 years, over the next 2 years. Other criteria for the study include:   a diagnosis of autosomal dominant polycystic kidney disease (ADPKD)  GFR >45 mL/min/1.73 m2  controlled blood pressure  no current tobacco use  no other clinical indication for a statin  women must not be ..read more
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PKD Treatment: Diet Maybe the Key, PKD Diagnosis: Urinary BioMarkers, Walk for PKD Home Stretch
PKD News Blog
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4y ago
PKD Treatment From University of California, Santa Barbara Reversing polycystic kidney disease Hereditary and relatively common, polycystic kidney disease (PKD) has long been thought to be progressive and irreversible, condemning its sufferers to a long, slow and often painful decline as fluid filled cysts develop in the kidneys, grow and eventually rob the organs of their function. Once their kidneys fail, PKD patients often require dialysis several times a week or must undergo a kidney transplant. To make matters worse, a host of other PKD-related conditions and complications add t ..read more
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PKD Alert: Participate in Accelerating Clinical Trials, Paying to Live: Transplant Costs
PKD News Blog
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4y ago
ACT Alert (Accelerating Clinical Trials) From PKD Foundation ADPKD patients needed for curcumin study Help play a key role in PKD research! Patient participation in clinical studies is essential to discovering treatments and a cure for PKD. Are you or someone you know interested in participating? There is a new research study being conducted to understand if the dietary supplement, curcumin, improves the function of blood vessels in children and young adults with autosomal dominant polycystic kidney disease (ADPKD). Study Details: Participants must be between the ages of 6 to 25 and diagn ..read more
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PKD: Discover Mechanism, PKD Fundraising, Crack Down on Dialysis Profits in California
PKD News Blog
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4y ago
Understanding How PKD Develops From Daily Nexus, University of California, Santa Barbara, by Jacqueline Wen UCSB Researchers Discover Mechanism Potentially Accelerating Progression of Polycystic Kidney Disease PKD progression is depicted, with a normal kidney represented on the right side of each diagram for comparison. / Courtesy of Wikimedia Commons Polycystic kidney disease is an inherited disorder causing clusters of cysts to form in the kidneys that may lead to eventual kidney failure. Autosomal dominant polycystic kidney disease (ADPKD) makes up about 90% of all PKD cases and affects ..read more
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PKD Research: Blocking Effects of MicroRNA-17, Dialysis Centers Limiting Kidney Transplants?
PKD News Blog
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4y ago
PKD Research From News Medical Promising new drug being developed for polycystic kidney disease Researchers have developed a potential new drug for the treatment of Polycystic kidney disease (PKD) – a deadly genetic condition affecting the kidneys that leads to formation of swellings or cysts within the kidney that cause it to fail. The results of the initial animal testing of the drug have been published in the latest issue of the Nature Communications. The study is titled, “Discovery and preclinical evaluation of anti-miR-17 oligonucleotide RGLS4326 for the treatment of polycystic kidne ..read more
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PKD: Major Contributing Cause Can be Kidney Stones, PKD Awareness Day
PKD News Blog
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4y ago
PKD Research From futurity.org HOW CRYSTALS TRIGGER CYST GROWTH IN SERIOUS KIDNEY DISEASE A process thought to protect the kidneys may trigger rapid cyst growth in people with polycystic kidney disease, a new study shows. For people with polycystic kidney disease (PKD), life can be a never-ending cycle of symptoms: aches and pains, abdominal swelling, kidney stones, and high blood pressure. The disease frequently leads, at worst, to a suite of major issues, including kidney failure, cysts in the liver, and vascular problems, including strokes. PKD is a “fairly common genetic disorder,” a ..read more
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