A new study reveals why some pancreatic and colorectal tumors resist targeted anti-Wnt drugs and suggests how to overcome it, offering new hope to patients with fully treatment-resistant cancers ..read more

A new type of investigational therapeutic for pancreatic cancer has shown unprecedented tumor-fighting abilities in preclinical models of the disease ..read more

Researchers describe a new technique for the minimally invasive removal of benign tumors located in the challenging posterior head of the pancreas (right side of abdomen, nestled in the curve of the duodenum (or first part of the small intestine). The technique, called the retro-laparoscopic approach, allows surgeons to safely and effectively remove these tumors without removing healthy pancreatic tissue, thereby preserving organ functionality ..read more

Our bodies depend on mucus to function properly. As it turns out, so do some cancer cells. Scientists discovered mucus not only allows young pancreatic cancer cells to grow, but also prevents them from transforming into deadlier, drug-resistant variants. Their discovery exposes a new vulnerability that may point toward future therapeutic strategies ..read more

Researchers have designed a candidate drug that could help make pancreatic cancer, which is almost always fatal, a treatable, perhaps even curable, condition ..read more

Older people may be at greater risk of developing pancreatic cancer and have poorer prognoses because of age-related changes in cells in the pancreas called fibroblasts, according to new research ..read more

Scientists have discovered that pancreatic ductal adenocarcinoma (PDAC) hijacks a protein called EN-1 to evade cancer-fighting genes during metastasis. Future drugs targeting EN-1 or related proteins in cancer cells could lead to better, more personalized treatments ..read more

A new study highlights the effectiveness of MDX-124, the first therapeutic drug to target annexin-A1, a protein which is overexpressed in several cancer types and promotes tumor progression ..read more

In a new study, researchers demonstrate that deregulation of a protein called RBFOX2, involved in RNA splicing, contributes to the progression and metastasis of pancreatic cancer ..read more

A drug screening system that models cancers using lab-grown tissues called organoids has helped uncover a promising target for future pancreatic cancer treatments ..read more