Creative Diagnostics Blog
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Get the latest blog product and research information from Creative Diagnostics providing latest research and news for ELISA kits, antigens and antibodies. Creative Diagnostics manufactures and markets worldwide the highest quality; innovative; specialty immunoassays. Utilizing advanced direct label technology to meet the throughput needs of both large and small independent and hospital..
Creative Diagnostics Blog
2d ago
What is COPD? Chronic obstructive pulmonary disease (COPD) is a chronic airway inflammatory disease characterized by progressive airflow limitation. The main symptoms are cough, expectoration, and progressive worsening dyspnea. As of 2017, COPD has become the third-largest cause of death in the world and the eighth-largest cause of life loss globally in 2019. The above […]
The post How Does COPD Affect the Lungs?-Animal Models Reveal the Truth first appeared on Creative Diagnostics ..read more
Creative Diagnostics Blog
2d ago
Autoimmune hemolytic anemia (AIHA) is a type of hemolytic anemia caused by the production of anti-self-erythrocyte antibodies due to immune dysfunction, binding to red blood cell surface antigens, or activating complement to accelerate the destruction of red blood cells. According to reports, the incidence of AIHA in adults is 0.08‰~0.3‰ per year, the prevalence is […]
The post Research on Autoimmune Hemolytic Anemia first appeared on Creative Diagnostics ..read more
Creative Diagnostics Blog
1M ago
Animal models are indispensable tools for studying the pathogenesis of many diseases, drugs and vaccines. Primates are close relatives of humans and are highly similar to humans in terms of organizational structure, immunity, physiology and metabolism. They are extremely precious and important experimental animals, and their application value far exceeds that of other species of […]
The post The Role of Non-human Primate Models in HIV Antiviral Drug Research first appeared on Creative Diagnostics ..read more
Creative Diagnostics Blog
1M ago
Brief Introduction to Avian Influenza Virus Avian influenza virus (AIV) is a common type A influenza virus, belonging to the genus influenza virus of the family Orthomyxoviridae, and is classified as a Class A epidemic by the World Organization for Animal Health (OIE). It is usually transmitted among poultry and birds, especially when accompanied by […]
The post Research Progress on Highly Pathogenic H5N1 Avian Influenza Virus first appeared on Creative Diagnostics ..read more
Creative Diagnostics Blog
2M ago
When Jenner discovered the smallpox virus in 1798, scientists realized that animal models could be a powerful tool for studying human infectious diseases. Animal models are commonly used to evaluate various immunological parameters: humoral and cell-mediated immunity, onset and duration of immunity, systemic and mucosal immunity, prevention of infection and reduction of disease spread, etc. […]
The post Introduction of Animal Models in Development of Vaccines first appeared on Creative Diagnostics ..read more
Creative Diagnostics Blog
2M ago
Over the past few decades, anti-tumor treatment has gradually evolved from traditional surgical resection, radiotherapy and chemotherapy to more precise molecularly targeted therapy and immunotherapy. These advances have improved the treatment of certain tumors to a certain extent. However, effective treatments are still limited for many tumors that are difficult to treat and prone to […]
The post Research on Chimeric Antigen Receptor-Mediated Anti-Tumor Cell Therapy first appeared on Creative Diagnostics ..read more
Creative Diagnostics Blog
4M ago
Varicella-zoster virus (VZV) is a pathogen widely present in the global population, infecting more than 90% of the world’s population. VZV primary infection often occurs in childhood, which can cause chickenpox characterized by systemic vesicular eruptions, and after infection, it can remain latent in the host’s neuronal cells. With age, immune dysfunction or other factors, the latent virus can be reactivated, spread along the peripheral nerves, and cause herpes zoster (HZ). With the popularization of vaccines, the incidence of varicella has been basically controlled, but HZ is more common in ..read more
Creative Diagnostics Blog
5M ago
Reprogramming of lipid metabolism has become an important feature of cancer. In order to adapt to the hypoxic and nutrient-deficient microenvironment, tumor cells, in addition to increasing glucose uptake and aerobic glycolysis, also need to undergo lipid metabolism reprogramming to enhance their biological behaviors. It is characterized by increased lipid uptake, lipid synthesis, fatty acid oxidation (FAO), and lipid storage. Increasing evidence shows that lipids serve as energy sources, membrane structures, signaling molecules (including biologically active lipids such as S1P, PGE2, and LPA ..read more
Creative Diagnostics Blog
5M ago
Autoimmune diseases are diseases caused by an autoimmune response. The role of the human immune system is to protect the body from pathogenic microorganisms and cancer cells. When the immune system accidentally attacks your body instead of protecting it, it will cause damage or dysfunction of its own tissues and organs, resulting in autoimmune diseases. As for why the immune system does this, it’s unclear why.
Autoimmune diseases can involve any organ and affect people of any age. More than 100 autoimmune diseases have been discovered. Common autoimmune diseases include systemic lupus erythem ..read more
Creative Diagnostics Blog
6M ago
Adeno-associated virus (AAV) is a small non-enveloped virus, belonging to the family Parvoviridae. It was first discovered in 1965 from contaminants of adenovirus isolates. It has an icosahedral structure on the outside and a diameter of about 26 nm. Its capsid protein is composed of It is composed of three proteins: VP1, VP2 and VP3. The genome of AAV is a single-stranded linear DNA, approximately 4700 bp, including two upstream and downstream open reading frames (ORFs): Rep and Cap. They are located between 2 T-shaped inverted terminal repeats (ITRs) each consisting of 145 nucleotides. The r ..read more