Metformin has been used in Long Covid and ME with some promising results. Metformin can be: However it may also With Ginseng / Red Ginseng / Padox Ginseng “Using metFORMIN together with ginseng may have additive effects on your blood sugar. You may need more frequent monitoring of your blood sugar to safely use both ..read more

My notes to make sense of what is vasodilating and what is vasoconstricting. It’s not as simple as needing one or the other as my ME body seems to have problems with both. Indeed there is disfunction reported “elevated levels of B2AdR autoantibodies (antibodies that attack the receptor) in ME/CFS… ß2AdR autoantibodies stimulate the ß2R ..read more

My notes to try and make sense of what helps the cholergenic system and what depletes it. Because I feel like it’s a balancing act rather than trying to make it do more or less. Anticholinesterase: prolong the existence of acetylcholine after it is released ANTICHOLINERGICThings that degrade or lower acetylcholine:Horsetail (also diuretic)Corn silkBarberry/berberine AmitriptylineDiphenhydramineKetofinProchlorperazineBenzosPseudoephedrine ..read more

I’ve had abdominal pain since around 2016 when my gallbladder flared to epic pukey proportions of contraction and disease. I saw the GP and a Gastro about continued pain around my upper gallbladder incisions after surgery. Nerve pain was suggested. At the same time I wasn’t able to wear anything around my waist and haven’t ..read more

When on 7mg/24hr patches I pushed through sleep disruption caused by the patches and while my nicotine disturbed sleep improved each day it was still pretty terrible. It also hasn’t recovered after 4+ weeks. Some of that though is a shift in my body systems since nicotine. So I am considering using 16hr patches and ..read more

Berberine is a natural alkaloid found in the roots, bark, and stems of hundreds of plants that have been used for medicinal purposes for thousands of years.https://www.healthydirections.com/articles/blood-sugar/top-berberine-questions Berberine is anticholergenic. Berberine, a naturally occurring isoquinoline alkaloid, shows anti-inflammatory, anticholinergic, antioxidative, and anticancer activitieshttps://www.spandidos-publications.com/10.3892/or.2017.5489 Uses BBR reduces virus replication and targets specific interactions between the virus and ..read more

IndexPossible benefitsMechanism of ActionSide EffectsDosageCalculate How Much Silymarin Possible Benefits To Follow Mechanism of Action Silymarin can control the production of Aβ by inhibiting the precursor substance of Aβ (β-amyloid precursor protein), and it can inhibit the polymerization of Aβ. Silymarin can also increase the acetylcholine content in the nervous system by inhibiting cholinesterase activity. At ..read more

Full ingredients for different brands of nicotine patches Nicotinell Patches The active substance is nicotine.The other ingredients are: acrylate esters vinylacetate, copolymers, fractionated coconut oil, methacrylic acid esters co-polymers, aluminised and siliconised polyester films. Source Niquitin Patches Nicotine, Drug Reservoir: Ethylene Vinyl Acetate Copolymer, Occlusive Backing: Polyethylene Terephthalate/ Ethylene Vinyl Acetate, Rate Controlling Membrane: Polyethylene ..read more

I will use this post to gather information I’ve found about any negatives or possible contraindicators for ME, LC and V treatment using nicotine patches. Liver nicotine accumulates in the intestine and activates a specific protein called AMPK. This sets off a chain of events that produce ceramides, lipids that accumulate in the liver and ..read more

Some notes to keep my head straight as I chop and change supps/vits to try and support weight loss which is currently stalled. Currently got in my arsenal: – Choline – helped with weight loss (but maybe as a laxative effect on fats), but gave me terrible migraine 3 days of one capsule. A tiny ..read more