Protein imbalances that increase brain cell excitability may explain why individuals with Alzheimer's disease (AD) who also experience seizures demonstrate more rapid cognitive decline than those who do not experience seizures ..read more

A simple blood test could allow doctors to determine whether a person may be at higher risk for stroke or cognitive decline during their lifetime, according to a new UCLA Health study ..read more

In a paper titled, "Multimodal MRI reveals brainstem connections that sustain wakefulness in human consciousness," published today in Science Translational Medicine, a group of researchers at Massachusetts General Hospital, a founding member of the Mass General Brigham healthcare system, and Boston Children's Hospital, created a connectivity map of a brain network that they propose is critical to human consciousness ..read more

Complex Regional Pain Syndrome (CRPS) is a chronic and debilitating pain disorder, typically considered lifelong with limited treatment options ..read more

Some families call it a trial of faith. Others just call it a curse. The progressive neurological disease known as spinocerebellar ataxia 4 (SCA4) is a rare condition, but its effects on patients and their families can be severe ..read more

A Brigham and Women’s Hospital study of 30 people found that, in patients with MS, advanced brain imaging could identify hidden inflammation not picked up on traditional MRIs ..read more

A genetic change or variant in a gene called SCN2A is a known cause of infantile seizures, autism spectrum disorder and intellectual disability, as well as a wide range of other moderate-to-profound impairments in mobility, communication, eating and vision ..read more

The potential association between psychiatric disorders in parents and the risk of the offspring developing autism spectrum disorder ..read more

A new UCLA Health study found certain genetic variants could help explain how long-term pesticide exposure could increase the risk of Parkinson's disease ..read more

Diagnosing rare Mendelian disorders is a labor-intensive task, even for experienced geneticists. Investigators at Baylor College of Medicine are trying to make the process more efficient using artificial intelligence ..read more