Elsevier - Journal of the Neurological Sciences
541 FOLLOWERS
The Journal of the Neurological Sciences provides a medium for the prompt publication of original articles in neurology and neuroscience from around the world. JNS places special emphasis on articles that provide guidance to clinicians around the world,report cutting-edge science related to neurology, educate readers about relevant and practical clinical outcomes in neurology.
Elsevier - Journal of the Neurological Sciences
2d ago
Endovascular therapy (EVT) reduces functional disability in patients with acute large vessel occlusion (LVO). However, the early neurological change after EVT may be limited in patients with intracranial atherosclerotic disease (ICAD ..read more
Superficial small cerebellar infarcts in cerebral amyloid angiopathy on 3 T MRI: A preliminary study
Elsevier - Journal of the Neurological Sciences
1w ago
Strictly superficial cerebellar microbleeds and cerebellar superficial siderosis have been considered markers of advanced cerebral amyloid angiopathy (CAA), but there are few studies on cerebellar ischemic lesions in CAA. We investigated the presence of superficial small cerebellar infarct (SCI) ≤15 mm and its relation to magnetic resonance imaging (MRI) markers in patients with probable CAA ..read more
Elsevier - Journal of the Neurological Sciences
1w ago
We completed a cross-sectional survey study to determine headache prevalence and its association with HIV characteristics among people living with HIV (PLHIV) in Lusaka, Zambia ..read more
Elsevier - Journal of the Neurological Sciences
1w ago
Dystonia is a movement disorder characterized by sustained or intermittent muscle contractions that lead to involuntary postures or repetitive movements. Genetic mutations are being increasingly recognized as a cause of dystonia. Deep brain stimulation (DBS) is one of the limited treatment options available. However, there are varying reports on its efficacy in genetic dystonias. This systematic review of the characteristics of genetic dystonias treated with DBS and their outcomes aims to aid in the evaluation of eligibility for such treatment ..read more
Elsevier - Journal of the Neurological Sciences
1w ago
Since April 1982, we have been conducting genetic analysis of autosomal dominant spinocerebellar degeneration in Hokkaido [1–3], the northernmost island of Japan, with a population of over 5 million people. Hokkaido is comparable to countries such as Denmark, Finland, and Norway. It is an island separated from the rest of Japan by the sea on all sides. Many of its inhabitants are descendants of settlers from various parts of Japan who arrived after the country's political reformation in 1868 (the Meiji Restoration ..read more
Elsevier - Journal of the Neurological Sciences
1w ago
HTLV-1 is a retrovirus virus that infects CD4+ T cells. Most people with HTLV-1 infection remain asymptomatic but some may develop conditions such as HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) or adult T-cell leukemia/lymphoma. HAM/TSP is characterized by progressive spasticity and weakness of the lower extremities, as well as loss of bladder control and sensory disturbances. The risk of developing HAM/TSP is associated with the duration of infection and the viral load. There is currently no cure for the disease but medications can help manage symptoms and slow the pro ..read more
Elsevier - Journal of the Neurological Sciences
1w ago
The traditional ALS multidisciplinary clinical practice of quarterly respiratory assessment may leave some individuals in danger of developing untreated respiratory insufficiency between visits or beginning non-invasive ventilation (NIV) later than would be optimal. Remote, or home-based, pulmonary function testing (rPFT) allows patients with ALS to perform regular respiratory testing at more frequent intervals in the home. The aim of this study was to determine the clinical benefit of weekly rPFT compared to standard, quarterly in-clinic respiratory assessments: the number of individuals with ..read more
Elsevier - Journal of the Neurological Sciences
1w ago
Non-invasive positive pressure ventilation (NIV) has become a widely accepted mode of management for ventilatory failure due to the otherwise fatal combination of upper and lower motor neuron weakness in amyotrophic lateral sclerosis (ALS). In most clinics NIV is commenced when there is evidence of respiratory failure, usually defined as a forced vital capacity (FVC) <50% predicted or a maximal inspiratory pressure (MIP) > minus 60 cm water. Slight variations around these criteria are also in use, but measurement of oxygen saturation in arterial blood, or pCO2 levels are not used as crit ..read more
Elsevier - Journal of the Neurological Sciences
1w ago
Multiple Sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system (CNS) characterized by damage to the myelin sheaths of oligodendrocytes. Currently, there is no specific biomarker to identify the disease; however, a diagnostic criterion has been established based on patient's clinical, laboratory, and imaging characteristics, which assists in identifying this condition.The primary method for diagnosing MS is the McDonald criteria, first described in 2001 and revised in the years 2005, 2012, and 2017 ..read more