Project Updates Project: Development of drug for the chemoprevention and/or treatment of HDGC Lyvianne Decourtye-Espiard PhD February 2022 We have proposed that the loss of E-cadherin due to pathogenic CDH1 mutations creates vulnerabilities in early-stage T1a gastric cancer cells that can be targeted with drugs. In this project, we have investigated these cells' vulnerability to histone deacetylases (HDACs) inhibitors, a class of enzymes with multiple roles in cancer development. HDAC inhibitors are the subject of strong research interest internationally, with over 97 clinical trials in numer ..read more

Universidade do Porto Grant Announcement: NICE Project - Nuclear biomarkers for predictive prognosis of hereditary diffuse gastric cancer E-cadherin germline mutations are causative events of Hereditary Diffuse Gastric Cancer (HDGC). Affected individuals are usually diagnosed at advanced stages of the disease, with diffuse gastric cancer frequently spreading beneath intact gastric mucosa. These carcinomas are typically unresponsive to adjuvant therapy and are associated with high relapse rates, resulting in a very poor prognosis. To date, most screening methods, such as endoscopy or magnetic ..read more

PURPOSE: To understand the process of discovery and decision making for adults with the CDH1 marker for hereditary diffuse gastric cancer and inherited breast cancer.     PARTICIPANTS & SETTING: Purposeful sampling included 20 participants: 17 adults (11 women and 6 men aged 23–77 years) recruited through the No Stomach For Cancer organization and 3 healthcare providers. Six participants were interviewed two times. Nineteen interviews were done via telephone, and one was conducted in person. METHODOLOGIC APPROACH: Grounded theory with constant comparison was used. FINDINGS: The ..read more

No Stomach For Cancer’s Grant for Gastric Cancer Innovation, Education, and Opportunity funds diverse research and programs No Stomach For Cancer (NSFC) is preparing to fund $232,000 in grants for stomach cancer research, education, and programs to improve patient outcomes. This is the largest grant total the organization has funded and coincides with their tenth anniversary. Paul Mansfield, M.D., vice president of Acute Care Services; Brian Badgwell, M.D., associate professor of Surgical Oncology; and Naruhiko Ikoma, M.D., assistant professor of Surgical Oncology at MD Anderson will receive ..read more

No Stomach For Cancer is pleased to announce the winners of the 2017 Grant for Gastric Cancer Innovation, Education, and Opportunity totaling $100,000. As part of the organization's global mission, it will fund significant research projects in the areas of immunotherapy, and blood biomarkers to predict early recurrence of stomach cancer. You can read the full press release here ..read more

Sonoma, CA - January 24, 2017 - John's March Against Stomach Cancer reached new heights at Sonoma Raceway on Saturday, Jan. 21, as the 6th annual event raised more than $23,000 for the fight against gastric cancer. Nearly 350 people turned out for the No Stomach For Cancer fundraiser, which generated over $5,000 more than its prior record-setting year in 2016. Walkers, runners and even dogs enjoyed a spin around the 2.52-mile, 12-turn road course on foot during the event, which is held in honor of John Cardinale, the long-time Sonoma Raceway spokesman who passed away in 2013 after a two-year ..read more

The idea of the Cancer Moonshot was first conceived in October 2015, when Vice President Joe Biden gave a speech calling for more attention to be given to developing a cure for cancer. “I believe that we need a moonshot in this country to cure cancer,” Biden said from the Rose Garden at the White House. “The president and I have already been working hard on increasing funding for research and development, because there are so many breakthroughs just on the horizon in science and medicine, the things that are just about to happen.” Over the last year, Biden has been working toward exactly that ..read more

No Stomach For Cancer is thrilled to announce a new partnership that will bring our resources in front of The Mighty's wide-reaching readership. We will now have a growing home page on The Mighty and appear on many stories on the site.   The Mighty is a story-based health community focused on improving the lives of people facing disease, disorder, mental illness and disability. More than half of Americans are facing serious health conditions or medical issues. They want more than information. They want to be inspired. The Mighty publishes real stories about real people facing real challenges ..read more

Congratulations to Hugo Pinheiro, recipient of the Mhari Saito Scholarship for 2015. Pinheiro is a post-doctoral fellow at the Institute of Pathology and Molecular Immunology of the University of Porto in Portugal. He has a special interest in rare syndromes, such as Hereditary Diffuse Gastric Cancer, which he says tend to attract less attention from the research community overall. Pinheiro plans to complete his MD in June of this year and continue his research with a focus on gastric cancer ..read more

Sonoma, CA - January 20, 2016 - A little rain could not dampen record-setting fundraising efforts at the 5th annual John's March Against Stomach Cancer at Sonoma Raceway on Saturday, Jan. 16. More than 200 people turned out under gray skies to participate in the fundraiser, which generated an event record of $17,629 for No Stomach For Cancer. Walkers, runners and even dogs enjoyed a spin around the 2.52-mile, 12-turn road course on foot during the event, which is held in honor of John Cardinale, the long-time Sonoma Raceway spokesman who passed away in 2013 after a two-year battle with stomac ..read more