Multi-institutional team led by Dr. David Kram of UNC School of Medicine, awarded $1.18 million funding award for Pediatric Brain Cancer Research TAMPA, Florida, April 12, 2024: A team of National Pediatric Cancer Foundation® (NPCF™) investigators from UNC Chapel Hill, University of Florida and Children’s National Medical Center have united to investigate a novel and innovative immunotherapy against relapsed Medulloblastoma with a $1.18 million grant. The project addresses medulloblastoma, the most common type of pediatric brain cancer, and when it recurs, it is nearly universally fata ..read more

David Loeb, MD PhD from Children’s Hospital at Montefiore awarded $150,000 grant for Ewing’s Sarcoma Research TAMPA, Florida, April 12, 2024: The National Pediatric Cancer Foundation® (NPCF™) has awarded Dr. David Loeb $150,000 for his current Ewing’s Sarcoma Research project titled: “One Carbon Is Not Enough–A Metabolic Attack On Ewing’s Sarcoma”. Ewing’s sarcoma is the second most common bone tumor in children and adolescents. Patients who present with localized disease have a survival rate of about 75% but at the cost of a significant burden of side effects and long-term health challenges ..read more

Revolutionary Immunotherapy Trial “TiNKS”, Helping Relapsed or Refractory Sarcoma Patients, Receives Additional $1.1 million for NK Cell Production TAMPA, Florida, April 15, 2024: The National Pediatric Cancer Foundation® (NPCF™) has awarded a $1.1 million supplemental grant to fund the production of NK cells for the multiple institutions participating in the TiNKS trial. The TiNKS trial is testing the safety and efficacy of a novel cell therapy, referred to as “universal donor TGF-beta-imprinted NK cells”, for their use in pediatric and young adult patients with sarcoma. This approach repre ..read more

Rising Hope Partner Brewery Thank you for becoming a Rising Hope partner brewery! Please fill out the information below and we will be in touch with more details and next steps. If you have additional please reach out to CGeib@NationalPCF.org. Name* First Last Email* Phone* Brewery Name* Section Break Company Address* Street Address Address Line 2 City State / Province / Region ZIP / Postal Code Afghanistan Albania Algeria American Samoa Andorra Angola Anguilla Antarctica Antigua and Barbuda Argentina Armenia Aruba Australia Austria Azerbaijan Bahamas Bahrain Bangladesh Barbados Belarus B ..read more

Meet Arianna! She is eight years old and battled Juvenile Myelomonocytic Leukemia. When Arianna was just 14 months old, she was diagnosed with Juvenile Myelomonocytic Leukemia which required a bone-marrow transplant and intense chemotherapy. Her body struggled with the transplant resulting in Graft versus Host Disease, Hyperkalemia, Hypovolemia, and other bloodstream diseases. Multiple sections of her small and large intestines were removed to combat the GVHD disease, which destroyed her intestines. Adrianna and her family spent 409 days in the hospital, and she currently depends on IV nu ..read more

Meet Rocco! He is five years old and battling Leukemia. Rocco was diagnosed with Leukemia in June 2021. Despite learning this news and then shortly after failing the induction phase of chemo, Rocco stayed strong and positive. After over two months of intense chemotherapy, Rocco’s body responded to the consolidation phase, and his cancer was virtually undetectable. Rocco is still in treatment that requires multiple hospital stays and has a long journey ahead of him, but that doesn’t change his positive mindset. Rocco continues to be happy, playful, and silly and can be stubborn sometimes ..read more

Meet Isabella! She is four years old and battled Hepatoblastoma. At just 16 months old, Isabella was diagnosed with cancer after three tumors were found on her liver, the largest being 11cm. She soon began her six cycles of treatment, which included four different types of chemotherapy. Halfway through her treatment, it was determined Isabella would need a life-saving liver transplant which she received a few months later. One of the most meaningful moments during her cancer journey was when Isabella took her first steps after surgery. Even though she was in pain, she had a smile on her f ..read more

Meet Aviana! She is six years old and battling Acute Lymphoblastic Leukemia. After suffering from a low-grade fever and rapid heartbeat and breathing rate, she went to the ER, where she was misdiagnosed with a viral infection. Her health declined over the next 24 hours, where she returned to the ER and was diagnosed with Acute Lymphoblastic Leukemia two days before her third birthday. Over the next two years, Aviana seemingly responded well to her chemotherapy but recently relapsed. She is currently receiving treatment and awaiting a bone marrow transplant. She is adorably kind, sassy, an ..read more

Meet Everly! She is four years old and battled Stage IV Glioblastoma. Everly was still in utero when the doctors found the mass on her left temporal lobe. She was delivered by an emergency C-section and rushed into open brain surgery three days later. With Stage IV brain cancer, she was given only a 5% chance of making it to her second birthday, but her parents refused to accept those odds and sought other opinions. A second opinion offered a 20% chance of survival with two years of chemotherapy or “until her body could no longer handle the treatments.” A 3rd opinion provided hope, and sh ..read more

Meet William! He is nine years old and battled Pre-B Cell Leukemia. When William was two and a half years old, he woke up screaming in pain. His parents thought it was another ear infection, but after rushing to the hospital, they learned William had Pre-B Cell Leukemia. The next four years were filled with multiple surgeries, lumbar punctures, chemotherapy, countless hospital stays, and a fight to save William’s life. Today, William is a joyful and fun boy who loves playing frisbee and baseball, climbing slides, eating chicken nuggets, and coloring. Please consider making a donati ..read more