The PLGA Fund at PBTF Sponsors PLGG/PLGA Coalition Meeting in Germany
PLGA Foundation | A Kids' Brain Tumor Cure Foundation
by Ryan S.
4y ago
On Monday, January 13, 2020, the PLGG/PLGA Coalition kicked off their 4th meeting in 6 years to discuss the most current scientific studies and best practices in clinical trials for treating PLGA patients. The goal of this coalition is to accelerate the pace of PLGA research by finding common ground for evaluating and treating PLGA patients as well as identifying the scientific direction to better understand these low-grade tumors and target them for eradication. This conference has been a catalyst for the most prolific period of PLGA research to date. Over two days in Ladenburg, Germany, the ..read more
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The Power of Human Cancer Genetics as Revealed by Pediatric Low-Grade Glioma
PLGA Foundation | A Kids' Brain Tumor Cure Foundation
by Ryan S.
4y ago
Through a unique international partnership between the PLGA Research Program at DFCI, the Everest Center PLGA Research Program at the German Cancer Research Center and Research Institute of the McGill University Medical Center, this newest publication summarizes The Power of Human Cancer Genetics as Revealed by Pediatric Low-Grade Glioma. In this article, Jones, Bandopadhayay and Jabado review novel diverse LGG entities, in which oncogenic processes show striking age-related neuroanatomical specificity (highlighting their close interplay with development); the opportunities they provide for ta ..read more
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The 8th Annual Camp Sunshine Pediatric Low-grade Astrocytoma Brain Tumor Week 2019
PLGA Foundation | A Kids' Brain Tumor Cure Foundation
by Ryan S.
4y ago
The 8th Annual Camp Sunshine Pediatric Low-grade Astrocytoma Brain Tumor Week 2019 was a “SOLD OUT” family experience with PLGA families from 17 different states and 1 European country in attendance! We’re excited to share that 30% of the families were ‘first timers’ at Camp Sunshine. They were welcomed with open arms by experienced campers and parents who have joined us in earlier summers. Campers enjoyed a full schedule of healthy mind and body family activities, kids’ sports, waterfront activities, adventure courses and so much more.  In addition, PLGA week welcomed VIP Researcher/Clinician ..read more
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Caught in the Act
PLGA Foundation | A Kids' Brain Tumor Cure Foundation
by Ryan S.
4y ago
First snapshots of cancer protein B-Raf illuminate basic biology, and can impact drug design for pediatric low grade glioma brain tumor patients. Researchers at the Blavatnik Institute at Harvard Medical School and Dana-Farber Cancer Institute, led by Michael J. Eck, professor of biological chemistry and molecular pharmacology, have been able to capture high-resolution 3D images of the well-known cancer driver, B-Raf, in its inactive or “off” state and in several active or “on” positions. These findings clarify how B-Raf functions normally in the body as well as what happens when mutations alt ..read more
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Pediatric Brain Tumor Foundation and American Association for Cancer Research Announce RFP for Research Grant to Optimize Drug Dosing Strategies for PLGA Patients
PLGA Foundation | A Kids' Brain Tumor Cure Foundation
by Ryan S.
4y ago
The Pediatric Brain Tumor Foundation’s PLGA Fund and the American Association for Cancer Research (AARC) are excited to announce a request for proposals for the inaugural Research Grant to Optimize Drug Dosing Strategies for Pediatric LGA/LGG Patients. This grant represents a joint commitment to promote and support innovative, collaborative research focused on the most common forms of pediatric brain cancer – low-grade glioma and astrocytoma (PLGA). While this project is specifically targeted to PLGA brain cancer, it holds great potential for all kids with brain tumors by laying the foundation ..read more
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Study Results: New PLGA Research Demonstrates the Power of Teamwork in Improving Outcomes for Kids with Brain Tumors
PLGA Foundation | A Kids' Brain Tumor Cure Foundation
by Ryan S.
4y ago
Children diagnosed with low-grade astrocytomas, the most common type of pediatric brain tumor, have close to 90 percent overall survival rates. However, the growth of the tumors and the standard treatments required to control them can cause serious side effects, including damaging developing brains and bodies. Researchers at Dana-Farber/Boston Children’s Cancer and Blood Disorders Center recently led an in-depth exploration into the genetic makeup of the individual brain tumor cells with the hope that the findings will lead to new treatments to minimize or avoid ill effects for young patients ..read more
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