For anyone facing a mastectomy, one of the main issues to be decided is whether to undergo reconstruction. In my case, it was never a matter of whether or not I would have reconstruction; it was a given based upon the recommendation of the cancer surgeon. I was very grateful that the decision was made immediately at the time of our discussing my second cancer surgery. This afforded me the opportunity to meet with the cosmetic surgeon who would be present at the cancer surgery and would be placing the expanders during the same surgery thus eliminating a separate surgery later on. The next cours ..read more

“Do not let the roles you play in life make you forget who you are.” – Roy T. Bennett The post Do not let the roles you play … appeared first on Let Life Happen ..read more

By: Erin Dahlstrom, Ph.D From: mdanderson.org PARP inhibitors are a type of targeted therapy commonly used to treat breast cancer and ovarian cancer, among others. They target PARP, or poly (ADP-ribose) polymerase, which is a protein in cells that helps repair damaged DNA. DNA damage is a normal part of a cell’s life cycle, and it doesn’t prevent cells from growing and dividing, as long as they can repair the damage. “PARP inhibitors are a class of drug that interferes with a cell’s ability to repair its DNA,” says Jennifer Litton, M.D., vice president of Clinical Research. How PARP inhibitors ..read more

“You were born to stand out, stop trying to fit in.” – Roy T. Bennett, The Light in the Hear The post You were born to stand out … appeared first on Let Life Happen ..read more

By: University of Colorado Cancer Center From: cancerhealth.com University of Colorado cancer researchers explore ways to overcome resistance to a standard treatment for triple-negative breast cancer Research led by University of Colorado Cancer Center members points to a combination of drugs as a potential treatment option for a type of aggressive breast cancer. Todd Pitts, PhD, and Jennifer Diamond, MD, co-authored a paper, published on March 1 in the journal Breast Cancer Research, on their study of ways to overcome resistance to doxorubicin, a type of chemotherapy drug that slows or stops ..read more

“Gratitude builds a bridge to abundance.” – Roy T. Bennett, The Light in the Heart The post Gratitude builds a … appeared first on Let Life Happen ..read more

By: Ashling Wahner From: onclive.com The FDA has granted orphan drug designation to utidelone injectable (UTD1) as a potential therapeutic option for patients with breast cancer brain metastases, according to an announcement from Biostar Pharma.1 Unlike most macromolecular drugs, utidelone can cross the blood-brain barrier because of its unique physiochemical characteristics and its insusceptibility to P-glycoprotein–mediated efflux. The orphan drug designation was based on data from 2 phase 2 trials. In the phase 2 UTOBIA-BM trial (NCT05781633) of UTD1 plus etoposide and bevacizumab (Avastin ..read more

“For just as each of us has one body with many members, and these members do not all have the same function, so in Christ we, though many, form one body, and each member belongs to all the others.” – Romans 12:4-5 The post For just as each of us has one body with many members … appeared first on Let Life Happen ..read more

Source : Hiroshima University From: eurekalert.org A team of researchers from Hiroshima University has discovered a molecule that promotes the production of cancer cells. This molecule may prove to be a potential therapeutic target in the treatment of triple-negative breast cancer, an aggressive form of breast cancer. Their work was published in the journal Molecular Cancer Research on January 18, 2024. Breast cancer is the most common type of cancer, ranking fifth among all cancers in cancer-related deaths. In 2020, there were 2.3 million new cases of breast cancers reported around ..read more

Oh, no!  Here it is – Friday and I was supposed to have my post done by Thursday. I haven’t missed a single deadline since I started writing my blog.  Even with the passing of my brother and a major surgery since I started writing, I didn’t miss a beat. So what in heavens name happened that I did not have my weekly writing done on time???  I forgot! “I just hope that I never make a choice to not live life to its fullest.  To me, there is absolutely nothing that is more important.” Barbara Jacoby Yes, it is that simple. There are so many reasons why this may have happened.&n ..read more