TTFields Meets Time to Intracranial Progression End Point in NSCLC Brain Metastases
Onclive » Lung Cancer
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5d ago
TTFields plus supportive care improved time to intracranial progression in patients with brain metastases from non–small cell lung cancer ..read more
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Perioperative Pembrolizumab Wins Approval in Europe for Resectable NSCLC at High Risk of Recurrence
Onclive » Lung Cancer
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5d ago
The European Commission has approved neoadjuvant pembrolizumab plus chemotherapy, followed by adjuvant pembrolizumab, for high-risk, resectable NSCLC ..read more
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Adagrasib Improves PFS, ORR in Previously Treated KRAS G12C–Mutant NSCLC
Onclive » Lung Cancer
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5d ago
Adagrasib improved progression-free survival and objective response rates vs docetaxel in pretreated KRAS G12C–mutant non–small cell lung cancer ..read more
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Tomivosertib Development in Frontline NSCLC Ending After Findings from KICKSTART Trial
Onclive » Lung Cancer
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5d ago
Data from the phase 2 KICKSTART trial of tomivosertib plus pembrolizumab do not support the combination's use in patients with non–small cell lung cancer ..read more
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Becotarug Plus Osimertinib Elicits Responses in EGFR Exon 20 Insertion+ NSCLC
Onclive » Lung Cancer
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2w ago
Becotarug plus osimertinib elicited responses with manageable safety in patients with non–small cell lung cancer and EGFR exon 12 insertion mutations ..read more
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Amivantamab Plus Chemo Nearly Doubles Time to Treatment Discontinuation, Need for Subsequent Therapy in EGFR Exon 20+ NSCLC
Onclive » Lung Cancer
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2w ago
Amivantamab plus chemotherapy extended the time to treatment discontinuation and subsequent therapy in EGFR exon 20 insertion–mutated NSCLC ..read more
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First-Line Pembrolizumab Plus Olaparib Maintenance Misses Survival End Points in Metastatic Nonsquamous NSCLC
Onclive » Lung Cancer
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2w ago
Pembrolizumab plus olaparib as first-line maintenance therapy did not improve survival in patients with metastatic nonsquamous non–small cell lung cancer ..read more
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Concurrent Durvalumab/CRT Does Not Confer Significant Survival Advantage in Unresectable Stage III NSCLC
Onclive » Lung Cancer
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2w ago
Durvalumab/chemoradiation did not significantly improve survival vs chemoradiation alone in patients with unresectable non–small cell lung cancer ..read more
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First-Line Anlotinib Plus Etoposide and Carboplatin Improves PFS in ES-SCLC
Onclive » Lung Cancer
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2w ago
Anlotinib plus etoposide, carboplatin, and placebo improved PFS vs etoposide plus carboplatin and 2 placebos in first-line ES-SCLC ..read more
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First-Line Osimertinib Plus Chemo Demonstrates Consistent Benefit in EGFR-Mutant NSCLC
Onclive » Lung Cancer
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2w ago
Osimertinib plus chemotherapy confers superior post-progression survival outcomes vs osimertinib alone in patients with EGFR-mutated NSCLC ..read more
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