For people with HIV, the risk of anal cancer varies according to their geographic region ..read more

One of the remaining mysteries of the human immune system is why a certain cell, called a B cell, which retains a memory for past infections -- ensuring we fight off diseases we have experienced before -- often only has a weak capacity to protect us from persistent infections. Researchers have essentially solved this mystery by discovering how chronic viral infection induces a previously unknown immune B memory cell that does not produce high levels of antibody ..read more

Scientists have identified promising real-world links between common HIV drugs and a reduced incidence of Alzheimer's disease ..read more

Scientists have identified sugar abnormalities in the blood that may promote biological aging and inflammation in people living with HIV ..read more

Researchers have developed a new method to isolate HIV from samples more easily, potentially making it easier to detect infection with the virus. They focus on peptide nanofibrils (PNFs) on magnetic microparticles, a promising tool and hybrid material for targeted binding and separation of viral particles ..read more

A team of researchers has successfully modified a naturally occurring chemical compound in the lab, resulting in advanced lead compounds with anti-HIV activity ..read more

Four children have remained free of detectable HIV for more than one year after their antiretroviral therapy (ART) was paused to see if they could achieve HIV remission, according to new research. The children, who acquired HIV before birth, were enrolled in a clinical trial in which an ART regimen was started within 48 hours of birth and then closely monitored for drug safety and HIV viral suppression. The outcomes reported today follow planned ART interruptions once the children met predefined virological and immunological criteria ..read more

Researchers have discovered a key mechanism used by Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8 (HHV8), to induce cancer. The research points to effective new treatment options for KSHV-associated cancers, including Kaposi's sarcoma, primary effusion lymphoma, and HHV8-associated multicentric Castleman disease ..read more

A professor has demonstrated a connection between viral damage to the gut and premature biological aging ..read more

Researchers found that PD-1-enhanced DNA vaccination can induce sustained virus-specific CD8+ T cell immunity in an AIDS monkey model. The vaccinated monkeys remained free of AIDS for six years and achieved virologic control without the need for combination antiretroviral therapy (cART), a treatment used to suppress viral replication in individuals living with human immunodeficiency virus (HIV). The study also found that polyfunctional and broadly reactive effector-memory virus-specific T cells were maintained in the protected experimental macaques for over six years. The findings provide supp ..read more