Cell cycle events are coordinated by cyclin-dependent kinases (CDKs) to ensure robust cell division. CDK4/6 and CDK2 regulate the growth 1 (G1) to synthesis (S) phase transition of the cell cycle by responding to mitogen signaling, promoting E2F ..read more

Certain people occupy topological positions within social networks that enhance their effectiveness at inducing spillovers. We mapped face-to-face networks among 24,702 people in 176 isolated villages in Honduras and randomly assigned villages to ..read more

The developmental decision made by malaria parasites to become sexual underlies all malaria transmission. Here, we describe a rich atlas of short- and long-read single-cell transcriptomes of over 37,000 Plasmodium falciparum cells across ..read more

B lymphocytes are essential mediators of humoral immunity and play multiple roles in human cancer. To decode the functions of tumor-infiltrating B cells, we generated a B cell blueprint encompassing single-cell transcriptome, B cell–receptor repertoire ..read more

Claudia Sheinbaum Pardo would be first researcher to lead the country, but critics worry she’ll be as hostile to science as her predecessor ..read more

The biologist and the poet shared deep sensibilities about the natural world ..read more

A well-researched account of the factors that drive pandemics misses an opportunity to indict broader social systems ..read more

HomeScienceVol. 384, No. 6695Groundwater flooding risks overlookedBack To Vol. 384, No. 6695 Full accessLetter Share on Groundwater flooding risks overlookedHamid M. Behzad and Yunpeng Nie [email protected]Authors Info & AffiliationsScience2 May 2024Vol 384, Issue 6695pp. 518-519DOI: 10.1126/science.ado6820 PREVIOUS ARTICLEPandemics and their accelerantsPreviousNEXT ARTICLENextgen Voices: Prevent ..read more

Add your voice to Science! Our new NextGen Voices survey is now open: What one change to scientifi c policy or culture would substantially decrease incidents of scientifi c misconduct or other unethical behavior ..read more

HomeScienceVol. 384, No. 6695A fellow engineer and presidential rivalBack To Vol. 384, No. 6695 Full accessFeature Share on A fellow engineer and presidential rivalRodrigo Pérez OrtegaAuthors Info & AffiliationsScience2 May 2024Vol 384, Issue 6695p. 504DOI: 10.1126/science.adq1748 PREVIOUS ARTICLEA scientist for presidentPreviousNEXT ARTICLEConductive hydrogels put electrons in chargeNext Conte ..read more