Targeting STING elicits GSDMD-dependent pyroptosis and boosts anti-tumor immunity in renal cell carcinoma
Oncogene
by Shengpan Wu, Baojun Wang, Hongzhao Li, Hanfeng Wang, Songliang Du, Xing Huang, Yang Fan, Yu Gao, Liangyou Gu, Qingbo Huang, Jianjun Chen, Xu Zhang, Yan Huang, Xin Ma
10h ago
Oncogene, Published online: 28 March 2024; doi:10.1038/s41388-024-03013-4 Targeting STING elicits GSDMD-dependent pyroptosis and boosts anti-tumor immunity in renal cell carcinoma ..read more
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SC912 inhibits AR-V7 activity in castration-resistant prostate cancer by targeting the androgen receptor N-terminal domain
Oncogene
by Qianhui Yi, Xiaojun Han, Henry G. Yu, Huei-Yu Chen, Dinghong Qiu, Jie Su, Rongtuan Lin, Gerald Batist, Jian Hui Wu
10h ago
Oncogene, Published online: 26 March 2024; doi:10.1038/s41388-024-02944-2 SC912 inhibits AR-V7 activity in castration-resistant prostate cancer by targeting the androgen receptor N-terminal domain ..read more
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ZEB1 controls a lineage-specific transcriptional program essential for melanoma cell state transitions
Oncogene
by Simon Durand, Yaqi Tang, Roxane M. Pommier, Valentin Benboubker, Maxime Grimont, Felix Boivin, Laetitia Barbollat-Boutrand, Eric Cumunel, Florian Dupeuble, Anaïs Eberhardt, Maud Plaschka, Stéphane Dalle, Julie Caramel
5d ago
Oncogene, Published online: 22 March 2024; doi:10.1038/s41388-024-03010-7 ZEB1 controls a lineage-specific transcriptional program essential for melanoma cell state transitions ..read more
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Colorectal cancer cells secreting DKK4 transform fibroblasts to promote tumour metastasis
Oncogene
by Xue Li, Yulin Chen, Ran Lu, Min Hu, Lei Gu, Qiaorong Huang, Wentong Meng, Hongyan Zhu, Chuanwen Fan, Zongguang Zhou, Xianming Mo
5d ago
Oncogene, Published online: 22 March 2024; doi:10.1038/s41388-024-03008-1 Colorectal cancer cells secreting DKK4 transform fibroblasts to promote tumour metastasis ..read more
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RNF126-mediated ubiquitination of FSP1 affects its subcellular localization and ferroptosis
Oncogene
by Wanqun Xie, Jiajia Wang, Shuaiwei Tian, Heng Zhao, Liangliang Cao, Zhuangzhuang Liang, Jian Yang, Yang Zhao, Baocheng Wang, Feng Jiang, Jie Ma
5d ago
Oncogene, Published online: 21 March 2024; doi:10.1038/s41388-024-02949-x RNF126-mediated ubiquitination of FSP1 affects its subcellular localization and ferroptosis ..read more
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Loss of RNA-binding protein CELF2 promotes acute leukemia development via FAT10-mTORC1
Oncogene
by Tengxiao Guo, Yuxia Wang, Xiaolu Sun, Shuaibing Hou, Yanjie Lan, Shengnan Yuan, Shuang Yang, Fei Zhao, Yajing Chu, Yuanwu Ma, Tao Cheng, Jia Yu, Bing Liu, Weiping Yuan, Xiaomin Wang
5d ago
Oncogene, Published online: 21 March 2024; doi:10.1038/s41388-024-03006-3 Loss of RNA-binding protein CELF2 promotes acute leukemia development via FAT10-mTORC1 ..read more
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E-cadherin interacts with EGFR resulting in hyper-activation of ERK in multiple models of breast cancer
Oncogene
by Gabriella C. Russo, Ashleigh J. Crawford, David Clark, Julie Cui, Ryan Carney, Michelle N. Karl, Boyang Su, Bartholomew Starich, Tung-Shing Lih, Pratik Kamat, Qiming Zhang, Praful R. Nair, Pei-Hsun Wu, Meng-Horng Lee, Hon S. Leong, Hui Zhang, Vito W. Rebecca, Denis Wirtz
5d ago
Oncogene, Published online: 20 March 2024; doi:10.1038/s41388-024-03007-2 E-cadherin interacts with EGFR resulting in hyper-activation of ERK in multiple models of breast cancer ..read more
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P53 modulates kinase inhibitor resistance and lineage plasticity in NF1-related MPNSTs
Oncogene
by Jamie L. Grit, Lauren E. McGee, Elizabeth A. Tovar, Curt J. Essenburg, Emily Wolfrum, Ian Beddows, Kaitlin Williams, Rachael T. C. Sheridan, Joshua L. Schipper, Marie Adams, Menusha Arumugam, Thomas Vander Woude, Sharavana Gurunathan, Jeffrey M. Field, Julia Wulfkuhle, Emanuel F. Petricoin III, Carrie R. Graveel, Matthew R. Steensma
2w ago
Oncogene, Published online: 13 March 2024; doi:10.1038/s41388-024-03000-9 p53 modulates kinase inhibitor resistance and lineage plasticity in NF1-related MPNSTs ..read more
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DHODH inhibition represents a therapeutic strategy and improves abiraterone treatment in castration-resistant prostate cancer
Oncogene
by Shaoqiang Guo, Miaomiao Miao, Yufeng Wu, Dongyue Pan, Qinyan Wu, Zhanfang Kang, Jianwen Zeng, Guoping Zhong, Chengfei Liu, Junjian Wang
2w ago
Oncogene, Published online: 13 March 2024; doi:10.1038/s41388-024-03005-4 DHODH inhibition represents a therapeutic strategy and improves abiraterone treatment in castration-resistant prostate cancer ..read more
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Neutrophils in cancer: dual roles through intercellular interactions
Oncogene
by Xinyu Yu, Changhui Li, Zijin Wang, Yaping Xu, Shiqun Shao, Fangwei Shao, Hua Wang, Jian Liu
2w ago
Oncogene, Published online: 12 March 2024; doi:10.1038/s41388-024-03004-5 Neutrophils in cancer: dual roles through intercellular interactions ..read more
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