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Multimodal exercise training to reduce frailty in people with multiple sclerosis: study protocol for a pilot randomized controlled trial

BMC » Pilot and Feasibility Studies

by Tobia Zanotto, Danya Pradeep Kumar, Abbas Tabatabaei, Sharon G. Lynch, Jianghua He, Trent J. Herda, Hannes Devos, Ramkumar Thiyagarajan, Lee Chaves, Kenneth Seldeen, Bruce R. Troen and Jacob J. Sosnoff

6d ago

Frailty, a syndrome characterized by decreased reserve and resistance to stressors across multiple physiologic systems, is highly prevalent in people living with multiple sclerosis (pwMS), independent of age o ..read more

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Feasibility of an early progressive resistance exercise program for acute Achilles tendon rupture

BMC » Pilot and Feasibility Studies

by Marianne Christensen, Karin Grävare Silbernagel, Jennifer A. Zellers, Inge Lunding Kjær and Michael Skovdal Rathleff

6d ago

Long-term strength deficits are common after Achilles tendon ruptures. Early use of progressive resistance exercises may help reduce strength deficits, but the feasibility of this approach is unknown. The aim ..read more

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Recommendations for optimising pilot and feasibility work in surgery

BMC » Pilot and Feasibility Studies

by K. Fairhurst, S. Potter, J. M. Blazeby and K. N. L. Avery

1w ago

Surgical trials are recognised as inherently challenging. Pilot and feasibility studies (PAFS) are increasingly acknowledged as a key method to optimise the design and conduct of randomised trials but remain l ..read more

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Online compassion-based self-help for depression in people with skin conditions: a feasibility study

BMC » Pilot and Feasibility Studies

by Elaine N. Clarke, Paul Norman and Andrew R. Thompson

1w ago

There is a need to develop psychological interventions for depression in people with skin conditions. This study aimed to investigate the acceptability, feasibility, and effects of an online compassion-based s ..read more

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A qualitative feasibility study of a prototype patient-centered video intervention to increase uptake of cancer genetic testing among Black Americans

BMC » Pilot and Feasibility Studies

by Katherine Clegg Smith, Rachel Grob, Michelle McCullough, Betty May, Emily Warne, Amanda Matchette, Avonne E. Connor and Kala Visvanathan

2w ago

Health advances due to developments in genomic medicine are unequally experienced in the USA; racial differences in the uptake of genetic testing are one factor in this disparity. In collaboration with Black p ..read more

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Improving medication prescribing-related outcomes for vulnerable elderly in transitions on high-risk medications (IMPROVE-IT HRM): a pilot randomized trial protocol

BMC » Pilot and Feasibility Studies

by Anne Holbrook, Dan Perri, Mitch Levine, Lawrence Mbuagbaw, Sarah Jarmain, Lehana Thabane, Jean-Eric Tarride, Lisa Dolovich, Sylvia Hyland, Victoria Telford, Jessyca Silva and Carmine Nieuwstraten

2w ago

Seniors with recurrent hospitalizations who are taking multiple medications including high-risk medications are at particular risk for serious adverse medication events. We will assess whether an expert Clinic ..read more

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A study protocol for a feasibility randomised controlled trial investigating videoendoscopic radical inguinal lymphadenectomy versus open radical inguinal lymphadenectomy in patients with penile cancer (VELRAD)

BMC » Pilot and Feasibility Studies

by Stanley Tang, Clare Akers, Hussain Alnajjar, Ben Ayres, Cinzia Baldini, Andrew Embleton-Thirsk, Kurinchi Gurusamy, Paul Hadway, Vivekanandan Kumar, Maurice Lau, Raj Nigam, Karl Pang, Arie Parnham, Elena Pizzo, Veronica Ranieri, Rowland Rees…

2w ago

Penile cancer is a rare male genital malignancy. Surgical excision of the primary tumour is followed by radical inguinal lymphadenectomy if there is metastatic disease detected by biopsy, fine needle aspiratio ..read more

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A feasibility study of mindfulness-based interventions for children

BMC » Pilot and Feasibility Studies

by Wai Man Sin, Mimi Mun Yee Tse, Joanne Wai Yee Chung and Sandy Pin Pin Choi

3w ago

Children’s overall psychological well-being is a concern for parents and adults worldwide. Mindfulness appears to be a promising intervention for enhancing children’s psychological well-being, and its effectiv ..read more

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Feasibility of diabetes self-management coaching program for individuals with type 2 diabetes in the Ethiopian primary care setting: a protocol for a feasibility mixed-methods parallel-group randomized controlled trial

BMC » Pilot and Feasibility Studies

by Fikadu Ambaw Yehualashet, Dorothy Kessler, Segenet Bizuneh and Catherine Donnelly

3w ago

Diabetes mellitus is the third most prevalent chronic metabolic disorder and a significant contributor to disability and impaired quality of life globally. Diabetes self-management coaching is an emerging empo ..read more

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Consolidated guidance for behavioral intervention pilot and feasibility studies

BMC » Pilot and Feasibility Studies

by Christopher D. Pfledderer, Lauren von Klinggraeff, Sarah Burkart, Alexsandra da Silva Bandeira, David R. Lubans, Russell Jago, Anthony D. Okely, Esther M. F. van Sluijs, John P. A. Ioannidis, James F. Thrasher, Xiaoming Li and Michael W. Beets

3w ago

In the behavioral sciences, conducting pilot and/or feasibility studies (PFS) is a key step that provides essential information used to inform the design, conduct, and implementation of a larger-scale trial. T ..read more

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