Deadly diseases and inflatable suits: how I found my niche in virology research Virologist Hulda Jónsdóttir studies some of the world’s most pathogenic viruses at the Spiez Laboratory in Switzerland ..read more

SARS-CoV-2 remodels the landscape of small non-coding RNAs with infection time and symptom severity ..read more

Diet switch pre-vaccination improves immune response and metabolic status in formerly obese mice Diet switching from high-fat to standard diet before influenza vaccination affects the metabolic state of T cells, restores their responses and improves vaccine efficacy in mice ..read more

The 2023 monkeypox outbreak was caused by a subclade IIb monkeypox virus (MPXV). Here, using advanced sequencing techniques, the authors identify variations on low-complexity regions of the MPXV genome and describe their potential as evolutionary drivers ..read more

Uncovered diversity of infectious circular RNAs: A new paradigm for the minimal parasites ..read more

An ancestral SARS-CoV-2 vaccine induces anti-Omicron variants antibodies by hypermutation Repeat vaccination with COVID-19 mRNA vaccines has been shown to increase breadth of the antibody response. Here the authors demonstrate that B cell clones induced by the ancestral COVID-19 vaccine develop into daughter clones with different reactivity to individual SARS-CoV-2 variants through the accumulation of somatic hypermutations ..read more

Blocking cell death limits lung damage and inflammation from influenza Animals that receive an inhibitor of an antiviral cell-death response called necroptosis are less likely to die of influenza even at a late stage of infection. This has implications for the development of therapies for respiratory diseases ..read more

Aged nasal epithelium is more prone to severe COVID-19 Age is the single greatest risk factor driving mortality after encounter with SARS-CoV-2. A new study shows that the composition of nasal epithelial cells varies across ages, facilitating SARS-CoV-2 growth and spread in older people ..read more

Bird flu outbreak in US cows: why scientists are concerned A virus that has killed hundreds of millions of birds has now infected cattle in six US states, but the threat to humans is currently low ..read more

Triple tandem trimer immunogens for HIV-1 and influenza nucleic acid-based vaccines ..read more